Esatenolol Dosage

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Dosage of Esatenolol in details

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The dosing regimen of Esatenolol is set individually. The usual dose for adults for oral administration at the beginning of treatment is 25-50 mg 1 time / day. If necessary the dose is increased gradually. If impaired renal function in patients with CC 15-35 ml / min - 50 mg / day; with CC less than 15 ml / min - 50 mg every other day.

The maximum dose for adults for oral administration is 200 mg / day in 1 or 2 doses.

Esatenolol interactions

Antiarrhythmic and anesthetic facilities increase cardiodepressive action of this drug (increased risk of developing bradycardia, arrhythmia, hypotension, heart failure).

Reserpine, methyldopa, clonidine, guanfacine, cardiac glycosides potentiate the negative chrono-, drome- and bathmotropic effect, insulin and other antidiabetic funds - hypoglycemia.

NSAIDs, estrogens, sympathomimetics, xanthines weaken the anti-hypertensive effect, absorption; sympatholytic, nitroglycerin, hydralazine, and other antihypertensive drugs increase it; antacids slow down this medication absorption.

Cimetidine inhibits the metabolism of Esatenolol.

This medication prolongs the action of anti-depolarizing muscle relaxant, anticoagulant effect of coumarins.

Three / tetracyclic antidepressants, antipsychotics, sedatives, hypnotics and alcohol potentiate CNS depression.

Esatenolol is incompatible with MAO inhibitors.


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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