Dosage of Neonal in details
Adult & childn ≥12 yr 1 caplet once daily. Childn 6-12 yr (>30 kg) 1 caplet once daily; <30 kg ½ caplet once daily.
Neonal interactions
Neonal is a potent liver enzyme inducer and may reduce the effect of coumarin for up to 6 wk. Additive CNS depression with alcohol. Reduced effect of tricyclic antidepressants (such as amitriptyline, clomipramine, desipramine, dosulepin, imipramine, melitracen etc), corticosteriods (such as hydrocortisone, dexamethasone etc), coumarins, darifenacin, disopyramide, doxorubicin, metronidazole, theophylline and tolvaptan. It is also likely that the drug level of lidocaine is reduced due to the increased liver enzyme activity. May reduce drug level of memantine. Increased sedation with thalidomide.
Potentially Fatal: Concurrent long-term use with phenmetrazine may result in psychosis. Concurrent use with sodium oxybate is contraindicated due to the additive CNS depressant effect. Neonal is a potent inducer of CYP3A4 and is expected to reduce the AUC of gefitinib significantly.
References
- FDA/SPL Indexing Data. "OHZ8QAW6YC: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
- MeSH. "Hypnotics and Sedatives". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "5-butyl-5-ethylbarbituric acid: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Neonal are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Neonal. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported frequency of use
No survey data has been collected yetConsumer reported doses
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Information checked by Dr. Sachin Kumar, MD Pharmacology
