Ofloxacin Dosage

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What is the dose of your medication?

Dosage of Ofloxacin in details

infoThe dose of a drug and Dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of drug given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient. Let us see what a dose of Ofloxacin drug for various conditions is.

Usual Adult Dose for Inhalation Bacillus anthracis:

Mass casualty treatment or prophylaxis of inhalational anthrax: 400 mg orally every 12 hours for 60 days

In case of intentional anthrax release as a biological weapon, the Working Group on Civilian Biodefense has suggested that, based on in vitro studies, ofloxacin could be used for postexposure prophylaxis or treatment of inhalational anthrax if ciprofloxacin and doxycycline are unavailable.

Usual Adult Dose for Anthrax Prophylaxis:

Mass casualty treatment or prophylaxis of inhalational anthrax: 400 mg orally every 12 hours for 60 days

In case of intentional anthrax release as a biological weapon, the Working Group on Civilian Biodefense has suggested that, based on in vitro studies, ofloxacin could be used for postexposure prophylaxis or treatment of inhalational anthrax if ciprofloxacin and doxycycline are unavailable.

Usual Adult Dose for Bronchitis:

400 mg orally every 12 hours for 10 days

Usual Adult Dose for Campylobacter Gastroenteritis:

400 mg orally every 12 hours

Therapy should be continued for approximately 3 days. However, most cases are self-limited, and prudent withholding of antibiotics in mild cases does not appear to slow recovery in most patients.

Usual Adult Dose for Cervicitis:

Due to Chlamydia trachomatis and/or Neisseria gonorrhoeae: 300 mg orally every 12 hours for 7 days

The patient's sexual partner(s) should also be evaluated/treated.

Due to high rates of resistance, the Centers for Disease Control and Prevention (CDC) do not recommend fluoroquinolones for treatment of gonococcal infections in the United States or for infections acquired in Asia, the Pacific Islands, England, and Wales. Ceftriaxone or oral cefixime are recommended as first-line treatment of gonorrhea in the United States or acquired in these areas. Antimicrobial susceptibility patterns should be monitored. The CDC recommends fluoroquinolones as alternative therapy only when gonococcal culture proves susceptibility.

Usual Adult Dose for Chancroid:

400 mg orally every 12 hours for 3 days, depending on the nature and severity of the infection

The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Chlamydia Infection:

300 mg orally twice daily for 7 days

The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Cystitis:

Uncomplicated: 200 mg orally every 12 hours

Duration: 3 days for infections due to Escherichia coli or Klebsiella pneumoniae; 7 days for infections due to other organisms

Usual Adult Dose for Epididymitis -- Non-Specific:

200 to 400 mg orally every 12 hours for 10 days

Usual Adult Dose for Epididymitis -- Sexually Transmitted:

300 mg orally every 12 hours for 10 days

The patient's sexual partner(s) should also be evaluated/treated.

Ofloxacin is recommended by the CDC for nongonococcal epididymitis in patients over 35 years old, for infections due to enteric organisms, or as an alternate agent for nongonococcal infections in patients with hypersensitivity to ceftriaxone or doxycycline.

Due to high rates of resistance, the CDC do not recommend fluoroquinolones for treatment of gonococcal infections in the United States or for infections acquired in Asia, the Pacific Islands, England, and Wales. Ceftriaxone is recommended as first-line treatment of gonococcal infections in the United States or acquired in these areas. Antimicrobial susceptibility patterns should be monitored. The CDC recommends fluoroquinolones as alternative therapy only when gonococcal culture proves susceptibility.

Usual Adult Dose for Gonococcal Infection -- Disseminated:

400 mg orally every 12 hours

Due to high rates of resistance, the CDC does not recommend fluoroquinolones for treatment of gonococcal infections in the United States or for infections acquired in Asia, the Pacific Islands, England, and Wales. Antimicrobial susceptibility patterns should be monitored. The CDC recommends fluoroquinolones as alternative therapy only when culture proves susceptibility.

The CDC currently recommends initial hospitalization and injectable antimicrobials (i.e., ceftriaxone, cefotaxime, ceftizoxime) for the treatment of disseminated gonococcal infection. Twenty-four to forty-eight hours after improvement begins, the patient can be switched to oral cefixime or cefpodoxime for a total course of at least 1 week.

Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin is also recommended to treat possible concurrent chlamydial infection.

The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Gonococcal Infection -- Uncomplicated:

Uncomplicated urethral/cervical gonococcal infections: 400 mg orally one time

Due to high rates of resistance, the CDC does not recommend fluoroquinolones for treatment of gonococcal infections in the United States or for infections acquired in Asia, the Pacific Islands, England, and Wales. Ceftriaxone or oral cefixime are recommended as first-line treatment of gonorrhea in the United States or acquired in these areas. Antimicrobial susceptibility patterns should be monitored. The CDC recommends fluoroquinolones as alternative therapy only when culture proves susceptibility.

Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin is also recommended to treat possible concurrent chlamydial infection.

The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Joint Infection:

Mild to moderate: 400 mg orally every 12 hours

Therapy should be continued for approximately 3 to 4 weeks, depending on the nature and severity of the infection. Longer therapy, 6 weeks or more, may be required for prosthetic joint infections. In addition, removal of the prosthesis is usually required to cure the infection.

Usual Adult Dose for Mycobacterium avium-intracellulare -- Treatment:

400 mg orally every 12 hours

The treatment of disseminated MAI infection in immunocompromised patients consists of either clarithromycin or azithromycin and 1 to 3 other drugs such as ethambutol, ciprofloxacin, ofloxacin, rifampin, rifabutin or amikacin. The optimal combination of drugs is not known. As long as a clinical and microbiological response is documented, therapy should be continued for life.

Usual Adult Dose for Nongonococcal Urethritis:

300 mg orally every 12 hours for 7 days

The patient's sexual partner(s) should also be evaluated/treated.

Usual Adult Dose for Osteomyelitis:

Mild to moderate: 400 mg orally every 12 hours

Therapy should be continued for approximately 4 to 6 weeks, depending on the nature and severity of the infection. Chronic osteomyelitis may require one to two months of additional antibiotic therapy and may benefit from surgical debridement.

Usual Adult Dose for Pelvic Inflammatory Disease:

400 mg orally every 12 hours

Therapy should be continued for approximately 14 days, depending on the nature and severity of the infection. The patient should be reevaluated and switched to parenteral antibiotics if she does not respond to oral therapy within 72 hours.

Due to high rates of resistance, the CDC does not recommend fluoroquinolones for treatment of gonococcal infections in the United States or for infections acquired in Asia, the Pacific Islands, England, and Wales. A parenteral cephalosporin is recommended as first-line treatment of gonococcal infections in the United States or acquired in these areas. Antimicrobial susceptibility patterns should be monitored. The CDC recommends fluoroquinolones as alternative therapy only when gonococcal culture proves susceptibility.

Usual Adult Dose for Plague:

Postexposure prophylaxis: 400 mg orally every 12 hours for 7 days

Treatment: 400 mg orally every 12 hours for 10 days

In case of intentional plague release as a biological weapon, the Working Group on Civilian Biodefense has suggested ofloxacin as an alternative agent to ciprofloxacin or doxycycline for treatment or postexposure prophylaxis of plague in a mass-casualty setting.

Usual Adult Dose for Pneumonia:

400 mg orally every 12 hours for 10 to 21 days

Usual Adult Dose for Prostatitis:

300 mg orally every 12 hours for 6 weeks

Usual Adult Dose for Pyelonephritis:

Uncomplicated: 400 mg orally every 12 hours for 14 days

Usual Adult Dose for Salmonella Enteric Fever:

200 to 400 mg orally every 12 hours for 7 to 14 days

Usual Adult Dose for Salmonella Gastroenteritis:

200 to 400 mg orally every 12 hours

Therapy should be continued for approximately 3 days. However, most cases are self-limited, and prudent withholding of antibiotics does not appear to slow recovery in most patients.

Usual Adult Dose for Shigellosis:

200 to 400 mg orally every 12 hours

Therapy should be continued for approximately 3 to 5 days in severely ill patients.

Usual Adult Dose for Skin or Soft Tissue Infection:

Uncomplicated: 400 mg orally every 12 hours

Therapy should be continued for approximately 7 to 10 days, or for 3 days after acute inflammation disappears, depending on the nature and severity of the infection. For more severe infections, such as diabetic soft tissue infections, 14 to 21 days of therapy may be required.

Usual Adult Dose for Traveler's Diarrhea:

300 mg orally every 12 hours

Therapy should be continued for approximately 3 days. However, most cases are self-limited, and prudent withholding of antibiotics in mild cases does not appear to slow recovery in most patients.

Usual Adult Dose for Tuberculosis -- Active:

300 mg to 400 mg orally or IV every 12 hours

May be given in combination with at least 3 other active drugs for treatment of multi-drug resistant TB, or when the patient is intolerant of first-line agents. AFB smear and culture should be monitored monthly.

Duration: Treatment for TB should generally continue for 18 to 24 months, or for 12 to 18 months after culture results are negative.

Usual Adult Dose for Urinary Tract Infection:

Uncomplicated: 200 mg orally every 12 hours

Duration: 3 days for infections due to Escherichia coli or Klebsiella pneumoniae; 7 days for infections due to other organisms

Complicated: 200 mg orally every 12 hours for 10 days

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What other drugs will affect Ofloxacin?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ofloxacin, especially:

  • theophylline;

  • a diuretic or "water pill";

  • heart rhythm medication--amiodarone, disopyramide, dofetilide, dronedarone, procainamide, quinidine, sotalol, and others;

  • medicine to treat depression or mental illness--amitriptylline, clomipramine, clozapine, desipramine, duloxetine, iloperidone, imipramine, nortriptyline, ziprasidone, and others; or

  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may interact with ofloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Ofloxacin interactions

infoInteractions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Ofloxacin, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the drug you take. Most drugs may interact with alcohol, tobacco, so be cautious. The below-mentioned interactions of Ofloxacin drug are worth giving a glance!

Probenecid decreases elimination. Antacids may reduce ofloxacin absorption, avoid for 2 hr either side of administration. Cimetidine may increase ofloxacin concentrations. Monitor blood glucose in patients on antidiabetic medication.

Potentially Fatal: Corticosteroids may increase risk of tendon rupture. Increases effects of oral anticoagulants, ciclosporin, theophylline. Increased risk of seizures with NSAIDs. Avoid in patients taking QT prolonging medication (e.g. class Ia or III antiarrythmics, astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines and some TCA).

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Reviews

The results of a survey conducted on nDrugs.com for Ofloxacin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Ofloxacin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported frequency of use

No survey data has been collected yet


2 consumers reported doses

What doses of Ofloxacin drug you have used?
The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, nDrugs.com website users used these doses of Ofloxacin drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users%
11-50mg1
50.0%
1-5mg1
50.0%


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