Rocepherin Uses

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How do you administer this medicine?

What is Rocepherin?

Rocepherin is used to treat bacterial infections in many different parts of the body. Rocepherin is also given before certain types of surgery to prevent infections.

Rocepherin belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, Rocepherin will not work for colds, flu, or other virus infections.

Rocepherin is available only with your doctor's prescription.

Rocepherin indications

infoAn indication is a term used for the list of condition or symptom or illness for which the drug is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of drugs used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician. The below description contains indications of Rocepherin drug. Have a glance and memorize few.

Before instituting treatment with Rocepherin, appropriate specimens should be obtained for isolation of the causative organism and for determination of its susceptibility to the drug. Therapy may be instituted prior to obtaining results of susceptibility testing.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Rocepherin for injection USP and other antibacterial drugs, Rocepherin for injection USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Rocepherin for injection USP is indicated for the treatment of the following infections when caused by susceptible organisms:

Lower Respiratory Tract Infections

caused by Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Escherichia coli, Enterobacter aerogenes, Proteus mirabilis or Serratia marcescens.

Acute Bacterial Otitis Media

caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta-lactamase producing strains) or Moraxella catarrhalis (including beta-lactamase producing strains).

NOTE: In one study lower clinical cure rates were observed with a single dose of Rocepherin for injection USP compared to 10 days of oral therapy. In a second study comparable cure rates were observed between single dose Rocepherin for injection USP and the comparator. The potentially lower clinical cure rate of Rocepherin for injection USP should be balanced against the potential advantages of parenteral therapy.

Skin and Skin Structure Infections

caused by Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Viridans group streptococci, Escherichia coli, Enterobacter cloacae, Klebsiella oxytoca, Klebsiella pneumoniae, Proteus mirabilis, Morganella morganii*, Pseudomonas aeruginosa, Serratia marcescens, Acinetobacter calcoaceticus, Bacteroides fragilis* or Peptostreptococcus species.

Urinary Tract Infections (complicated and uncomplicated)

caused by Escherichia coli, Proteus mirabilis, Proteus vulgaris, Morganella morganii or Klebsiella pneumoniae.

Uncomplicated Gonorrhea (cervical/urethral and rectal)

caused by Neisseria gonorrhoeae, including both penicillinase- and nonpenicillinase-producing strains, and pharyngeal gonorrhea caused by nonpenicillinase-producing strains of Neisseria gonorrhoeae.

Pelvic Inflammatory Disease

caused by Neisseria gonorrhoeae. Rocepherin sodium, like other cephalosporins, has no activity against Chlamydia trachomatis. Therefore, when cephalosporins are used in the treatment of patients with pelvic inflammatory disease and Chlamydia trachomatis is one of the suspected pathogens, appropriate antichlamydial coverage should be added.

Bacterial Septicemia

caused by Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae or Klebsiella pneumoniae.

Bone and Joint Infections

caused by Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae or Enterobacter species.

Intra-Abdominal Infections

caused by Escherichia coli, Klebsiella pneumoniae, Bacteroides fragilis, Clostridium species (Note: most strains of Clostridium difficile are resistant) or Peptostreptococcus species.

Meningitis

caused by Haemophilus influenzae, Neisseria meningitidis or Streptococcus pneumoniae. Rocepherin for injection USP has also been used successfully in a limited number of cases of meningitis and shunt infection caused by Staphylococcus epidermidis* and Escherichia coli.*

*Efficacy for this organism in this organ system was studied in fewer than ten infections.

Surgical Prophylaxis

The preoperative administration of a single 1 g dose of Rocepherin for injection USP may reduce the incidence of postoperative infections in patients undergoing surgical procedures classified as contaminated or potentially contaminated (e.g., vaginal or abdominal hysterectomy or cholecystectomy for chronic calculous cholecystitis in high-risk patients, such as those over 70 years of age, with acute cholecystitis not requiring therapeutic antimicrobials, obstructive jaundice or common duct bile stones) and in surgical patients for whom infection at the operative site would present serious risk (e.g., during coronary artery bypass surgery). Although Rocepherin for injection USP has been shown to have been as effective as cefazolin in the prevention of infection following coronary artery bypass surgery, no placebo-controlled trials have been conducted to evaluate any cephalosporin antibiotic in the prevention of infection following coronary artery bypass surgery.

When administered prior to surgical procedures for which it is indicated, a single 1 g dose of Rocepherin for injection USP provides protection from most infections due to susceptible organisms throughout the course of the procedure.

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How should I use Rocepherin?

Use Rocepherin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Rocepherin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Rocepherin at home, a health care provider will teach you how to use it. Be sure you understand how to use Rocepherin. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Rocepherin is light yellow to amber in color. Do not use Rocepherin if it contains particles, is cloudy or discolored, or if the vial or container is cracked or damaged in any way.
  • To clear up your infection completely, use Rocepherin for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Rocepherin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Rocepherin.

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Uses of Rocepherin in details

infoThere are specific as well as general uses of a drug or medicine. A drug can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some drugs can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it. The below information contains the uses of Rocepherin drug.

Rocepherin is used to treat bacterial infections of the brain respiratory tract ear abdomen abdominal wall, urinary tract and kidney, bones, joints, and skin or soft tissues. It is also used in the management of fever with low white blood cells (neutropenia), surgical site infections, joint pain caused by parasite ticks (Lyme disease), typhoid, paratyphoid and sexually transmitted infections (gonorrhea, syphilis).

Rocepherin description

infoPharmacology is a crucial part of medicine wherein various drugs are used to advance the well-being of an individual. Some drugs cure the infection or a disease; few prevent the occurrence of a symptom or a disease, and few are used in long-term treatment of the disease. Drugs are obtained from the plants as well as they can be synthesized organically. The drugs are used in various combinations or a single drug by the pharmaceutical industry during its preparation. The half-life of each drug is different, and the dosage of the drug depends on the half-life of the drug. The below information gives the detailed description of Rocepherin drug.

A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears. [PubChem]

Active ingredient matches for Rocepherin:

Ceftriaxone


Unit description / dosage (Manufacturer)Price, USD
Injectable; Injection; Ceftriaxone Sodium 1 g

List of Rocepherin substitutes (brand and generic names):

Injectable; Injection; Ceftriaxone Sodium 250 mg (Roche)
Injectable; Injection; Ceftriaxone Sodium 500 mg (Roche)
Injectable; Injection; Ceftriaxone Sodium 1 g (Roche)
Injectable; Injection; Ceftriaxone Sodium 2 g (Roche)
Injectable; Injection; Ceftriaxone Sodium 10 g (Roche)
Rocephin 1 g x 1's (Roche)$ 24.20
Rocephin 250 mg x 1's (Roche)
Rocephin 500 mg x 1's (Roche)$ 13.71
Rocephin 1 g x 5's (Roche)
Rocephin 250 mg x 5's (Roche)
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Rocephin 500 mg x 5's (Roche)
Rocephin 1 g/3.5 mL x 1's (Roche)
Rocephin 250 mg/2 mL x 1's (Roche)
Rocephin 500 mg/2 mL x 1's (Roche)
Rocephin 1 g/10 mL x 1's (Roche)
Rocephin 250 mg/5 mL x 1's (Roche)
Rocephin 500 mg/5 mL x 1's (Roche)
Rocephin 2 g x 1's (Roche)
Rocephin / vial 250 mg x 1's (Roche)$ 7.98
Rocephin 1 g x 10 Bottle (Roche)
Rocephin 2 g x 1 Bottle (Roche)
Rocephin 2 g x 10 Bottle (Roche)
Rocephin 250 mg x 10 Bottle (Roche)
Rocephin 500 mg x 10 Bottle (Roche)
Rocephin powd for IM/IV inj 1 g 5 x 1's (Roche)
Rocephin powd for IM/IV inj 250 mg 5 x 1's (Roche)
Rocephin powd for IM/IV inj 500 mg 5 x 1's (Roche)
Rocephin powd for inj 1 g 1's (Roche)
Rocephin powd for inj 2 g 1's (Roche)
Rocephin powd for inj 250 mg 1's (Roche)
Rocephin powd for inj 500 mg 1's (Roche)
Rocephin IM inj 1 g/3.5 mL 1's (Roche)
Rocephin IM inj 250 mg/2 mL 1's (Roche)
Rocephin IM inj 500 mg/2 mL 1's (Roche)
Rocephin IV inj 1 g/10 mL 1's (Roche)
Rocephin IV inj 250 mg/5 mL 1's (Roche)
Rocephin IV inj 500 mg/5 mL 1's (Roche)
Rocephin inj 1 g 10 mL x 1's (Roche)
Rocephin injection, powder, for solution 1 g/1 (Roche)
Injectable; Injection; Ceftriaxone Sodium 500 mg
Injectable; Injection; Ceftriaxone Sodium 1 g
Injectable; Injection; Ceftriaxone Sodium 500 mg
Injectable; Injection; Ceftriaxone Sodium 1 g
Injectable; Injection; Ceftriaxone Sodium 10 mg / ml
Injectable; Injection; Ceftriaxone Sodium 20 mg / ml
Injectable; Injection; Ceftriaxone Sodium 40 mg / ml
Injectable; Injection; Ceftriaxone Sodium 250 mg (Roche)
Injectable; Injection; Ceftriaxone Sodium 500 mg (Roche)
Injectable; Injection; Ceftriaxone Sodium 1 g (Roche)
Injectable; Injection; Ceftriaxone Sodium 2 g (Roche)
Rocephine 1 g x 10 Bottle (Roche)
Rocephine 2 g x 1 Bottle (Roche)
Rocephine 2 g x 10 Bottle (Roche)
Rocephine 250 mg x 10 Bottle (Roche)
Rocephine 500 mg x 10 Bottle (Roche)
Injectable; Injection; Ceftriaxone Sodium 250 mg
Injectable; Injection; Ceftriaxone Sodium 500 mg
Injectable; Injection; Ceftriaxone Sodium 1 g
Injectable; Injection; Ceftriaxone Sodium 2 g
Rocephine 1 g x 10 Bottle
Rocephine 2 g x 1 Bottle
Rocephine 2 g x 10 Bottle
Rocephine 250 mg x 10 Bottle
Rocephine 500 mg x 10 Bottle

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