Carbachol Uses

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What is Carbachol?

Contracting the pupil during and immediately following surgery. It is also reduces eye pressure in the first 24 hours after cataract surgery.

Carbachol ocular is a cholinergic agent/miotic. The exact way Carbachol ocular works is not fully understood. It works by constricting the iris and other parts of the eye, resulting in reduction of eye pressure.

Carbachol indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Carbachol reduces the pressure in the eye by increasing the amount of fluid that drains from the eye. Carbachol also causes the pupil to become smaller and reduces its response to light or dark conditions.

Carbachol is used to treat glaucoma by lowering the pressure inside the eye.

Carbachol may also be used for purposes other than those listed in this medication guide.

How should I use Carbachol?

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Use Isopto Carbachol drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Isopto Carbachol drops is for topical use in the eye only. It is not for injection.
  • To use Isopto Carbachol drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
  • Continue to use Isopto Carbachol drops even if you feel well. Do not miss any doses.
  • If you miss a dose of Isopto Carbachol drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Isopto Carbachol drops.

Carbachol description

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An antifungal antibiotic. Carbachol may be given by mouth in the treatment of tinea infections.

Carbachol dosage

Usual Adult Dose for Intraocular Hypertension

Instill no more than 0.5 mL into the anterior chamber of the affected eye(s) for the production of miosis during ocular surgery.

Comments:

-Miosis is usually maximal within 2 to 5 minutes after application.

-This drug may be instilled before or after securing sutures.

Uses:

-To obtain miosis during surgery

-To reduce the intensity of intraocular pressure elevation in the first 24 hours following cataract surgery

Usual Adult Dose for Production of Miosis

Instill no more than 0.5 mL into the anterior chamber of the affected eye(s) for the production of miosis during ocular surgery.

Comments:

-Miosis is usually maximal within 2 to 5 minutes after application.

-This drug may be instilled before or after securing sutures.

Uses:

-To obtain miosis during surgery

-To reduce the intensity of intraocular pressure elevation in the first 24 hours following cataract surgery

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

-The manufacturer product information should be consulted.

-Intraocular solution: For single-dose intraocular use only; discard unused portion

-Ophthalmic solution: For topical use only; not for injection

Carbachol interactions

See also:
What other drugs will affect Carbachol?

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Before using this medication, tell your doctor if you are using another eye medication, especially if it is a nonsteroidal anti-inflammatory drug (NSAID) such as flurbiprofen (Ocufen), suprofen (Profenal), diclofenac (Voltaren), or ketorolac (Acular).

Do not use other eye medications during treatment with Carbachol except under the direction of your doctor.

Drugs other than those listed here may also interact with Carbachol. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Carbachol side effects

See also:
What are the possible side effects of Carbachol?

Applies to Carbachol: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by Carbachol (the active ingredient contained in Carbachol). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Carbachol, check with your doctor or nurse as soon as possible:

Rare

  • Veil or curtain appearing across part of vision
Symptoms of too much medicine being absorbed into the body
  • Diarrhea, stomach cramps or pain, or vomiting
  • fainting
  • flushing or redness of face
  • frequent urge to urinate
  • increased sweating
  • irregular heartbeat
  • shortness of breath, wheezing, or tightness in chest
  • unusual tiredness or weakness
  • watering of mouth

Minor Side Effects

Some of the side effects that can occur with Carbachol may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

  • Blurred vision or change in near or distance vision
  • eye pain
  • stinging or burning of the eye
Less common:
  • Headache
  • irritation or redness of eyes
  • twitching of eyelids

Carbachol contraindications

See also:
What is the most important information I should know about Carbachol?

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You should not use Carbachol if you are allergic to it, or if you have swelling of your iris (the colored part of your eye).

Before using this medication, tell your doctor if you have had a recent eye injury, heart failure or recent heart attack, high or low blood pressure, asthma, a stomach ulcer, an overactive thyroid, urination problems, Parkinson's disease, if you have had a retinal tear, if you are nearsighted, or if you have had cataract surgery.

Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Do not use this medication while wearing contact lenses. Carbachol may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using Carbachol before putting in your contact lenses.

Call your doctor at once if you have vision problems, seeing "floaters" in your vision, or severe burning, stinging, or if you have eye irritation after using the eye drops.



Active ingredient matches for Carbachol:

Carbachol


Unit description / dosage (Manufacturer)Price, USD
Liquid; Subcutaneous; Carbachol 0.25 mg / ml
Tablet; Oral; Carbachol 2 mg
Solution; Intraocular; Carbachol 0.01%
Isopto Carbachol 3% Solution 15ml Bottle$ 61.76
Carbachol 99% powder$ 53.10
Isopto Carbachol 1.5% Solution 15ml Bottle$ 48.64
Isopto Carbachol 1.5% Solution 30ml Bottle$ 44.99
Miostat vial$ 32.40
Isopto carbachol 3% drops$ 3.51
Isopto carbachol 1.5% drops$ 3.07
Isopto Carbachol 3 % Solution$ 0.91
Isopto Carbachol 1.5 % Solution$ 0.76
Carbachol tablet 2 mg (Mylan Pharmaceuticals Ulc (Canada))

List of Carbachol substitutes (brand and generic names):

Carbal 0.01 % x 1.5 mL x 10's
Solution; Intraocular; Carbachol 0.01% (Novartis ophthalmics)
1.5 milliliter in 1 vial, glass (Novartis ophthalmics)
Carbastat solution 0.01 % (Novartis ophthalmics)
Injectable; Injection; Carbachol 1 mg / ml
Liquid; Ophthalmic; Carbachol 1.5% (Alcon Laboratories, Inc.)

References

  1. DailyMed. "CARBACHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "carbachol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "carbachol". http://www.drugbank.ca/drugs/DB00411 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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