Rohto Antibacterial Eye Drops Uses

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Consists of - aminocaproic acid, chlorpheniramine maleate, Sulfamethoxazole sodium

What is Chlorpheniramine maleate (Rohto Antibacterial Eye Drops)?

Relieving symptoms of sinus congestion, sinus pressure, runny nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (eg, colds), allergies, and hay fever. It may also be used for other conditions as determined by your doctor.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) is an antihistamine. It works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Temporary relief of sneezing, itchy, watery eyes, itchy nose or throat, and runny nose caused by hay fever (allergic rhinitis), or other respiratory allergies.

How should I use Chlorpheniramine maleate (Rohto Antibacterial Eye Drops)?

Use Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) may be taken with or without food.
  • Shake well before using.
  • Use the dropper that comes with Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Chlorpheniramine maleate (Rohto Antibacterial Eye Drops), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine maleate (Rohto Antibacterial Eye Drops).

Uses of Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

This medication is used to treat itching and pain caused by minor burns/cuts/scrapes, sunburn, insect bites, minor skin irritations, or rashes from poison ivy, poison oak, or poison sumac.

Diphenhydramine belongs to a class of drugs known as antihistamines. It works by preventing the effects of a certain natural substance (histamine) that causes itching. Calamine helps to dry the oozing and weeping caused by irritation from poisonous plants.

Use of this medication is not recommended in children younger than 2 years unless directed by the doctor.

How to use Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) topical

Use this medication on the skin only. Some products may need to be shaken well before use. Follow all directions on the product package, or use as directed by your doctor. Before applying, clean the affected area with soap and water. Gently pat dry. Apply to the affected area as directed, usually 3 to 4 times a day. Wash hands immediately after use, unless the area being treated includes the hands.

Do not use on large areas of the body or apply more often than directed. Do not use on chickenpox or measles. Do not use with other products that contain diphenhydramine (e.g., allergy medication taken by mouth). Your condition will not clear faster, but side effects may be increased.

Avoid getting the product in your eyes, nose, ears, or mouth. If the medication gets in these areas, rinse the area right away with clean water.

Tell your doctor if your condition persists or worsens after 7 days of treatment. If you think you may have a serious medical problem, seek immediate medical attention.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) description

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A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) dosage

Tab Adult & childn >12 yr 1 tab tds-qds. Childn 6-12 yr ½ tab tds-qds. Syr Adult 5 mL tds-qds. Childn 6-12 yr 2.5 mL tds-qds, 2-5 yr 1.25 mL tds-qds.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) interactions

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What other drugs will affect Chlorpheniramine maleate (Rohto Antibacterial Eye Drops)?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g., atropine, belladonna alkaloids), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), scopolamine, tricyclic antidepressants (e.g., amitriptyline).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

Chlorpheniramine is very similar to dexchlorpheniramine. Do not use medications containing dexchlorpheniramine while using chlorpheniramine.

This medication may interfere with certain laboratory tests (including allergy skin testing), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) side effects

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What are the possible side effects of Chlorpheniramine maleate (Rohto Antibacterial Eye Drops)?

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Drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat may occur. These effects may decrease as your body adjusts to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. Chlorpheniramine can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.

If you are using a sustained-release product, an empty tablet shell may appear in your stool. This is harmless.

If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (e.g., hallucinations, irritability, nervousness, confusion), ringing in the ears, trouble urinating.

Tell your doctor right away if any of these rare but very serious side effects occur: easy bruising/bleeding, fast/irregular heartbeat, seizure.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Chlorpheniramine maleate (Rohto Antibacterial Eye Drops) contraindications

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What is the most important information I should know about Chlorpheniramine maleate (Rohto Antibacterial Eye Drops)?

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Hypersensitivity to antihistamines; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO therapy; use in newborn or premature infants and in breast-feeding mothers.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually E. coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the absence of obstructive uropathy or foreign bodies.

Meningococcal meningitis prophylaxis when sulfonamide-sensitive group A strains are known to prevail in family groups or larger closed populations. (The prophylactic usefulness of sulfonamides when group B or C infections are prevalent has not been proven and in closed population groups may be harmful.)

Acute otitis media due to Haemophilus influenzae when used concomitantly with adequate doses of penicillin.

Trachoma. Inclusion conjunctivitis. Nocardiosis. Chancroid. Toxoplasmosis as adjunctive therapy with pyrimethamine. Malaria due to chloroquine-resistant strains of Plasmodium falciparum, when used as adjunctive therapy.

Important Note: In vitro sulfonamide susceptibility tests are not always reliable. The test must be carefully coordinated with bacteriologic and clinical response. When the patient is already taking sulfonamides, follow-up cultures should have aminobenzoic acid added to the culture media.

Currently, the increasing frequency of resistant organisms is a limitation of the usefulness of antibacterial agents including the sulfonamides, especially in the treatment of chronic and recurrent urinary tract infections.

Wide variation in blood concentrations may result with identical doses. Blood concentrations should be measured in patients receiving sulfonamides for serious infections. Free sulfonamide blood concentrations of 5 to 15 mg/100 mL may be considered therapeutically effective for most infections, with blood concentrations of 12 to 15 mg/100 mL optimal for serious infections; 20 mg/100 mL should be the maximum total sulfonamide concentration, since adverse reactions occur more frequently above this concentration.

Uses of Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) is used to treat malaria, conjunctivitis (irritation and redness in the membrane covering the eye) due to chlamydia, toxoplasmosis, and urinary tract infections.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) description

A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the trimethoprim-Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) combination is the form most often used. It is sometimes used alone as an antimalarial. trimethoprim resistance has been reported.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) dosage

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) Dosage

Applies to the following strengths: 500 mg

Usual Adult Dose for:

  • Bacterial Infection
  • Cystitis
  • Inclusion Conjunctivitis
  • Malaria
  • Otitis Media
  • Toxoplasmosis
  • Trachoma

Additional dosage information:

  • Renal Dose Adjustments
  • Liver Dose Adjustments
  • Precautions
  • Dialysis

Usual Adult Dose for Bacterial Infection

Mild to moderate infections: 2 g orally one time followed by 1 g orally twice a day.

Severe infections: 2 g orally one time followed by 1 g orally 3 times a day.

Usual Adult Dose for Cystitis

2 g orally once, followed by 1 g orally every 6 to 12 hours for 3 to 7 days.

Usual Adult Dose for Inclusion Conjunctivitis

2 g orally one time, followed by 1 g orally every 6 to 12 hours for 21 days.

Usual Adult Dose for Malaria

2 g orally one time, followed by 1 g orally every 8 hours for 7 to 10 days. Used as adjunctive therapy in cases of chloroquine-resistant Plasmodium falciparum.

Usual Adult Dose for Otitis Media

2 g orally one time, followed by 1 g orally every 6-12 hours for 10 to 14 days. Recommend administering in combination with erythromycin or trimethoprim.

Usual Adult Dose for Toxoplasmosis

2 g orally one time, followed by 1 g orally every 8 hours for 2 to 4 months. Should administer with pyrimethamine 75 mg one time followed by 25 mg orally once a day. Folinic acid 3 to 9 mg orally 2 to 3 times a week is recommended to prevent bone marrow toxicity.

Usual Adult Dose for Trachoma

2 g orally once, followed by 1 g orally every 6-12 hours. Therapy should be continued for approximately 21 days, depending on the nature and severity of the infection.

Renal Dose Adjustments

CrCl < 10 mL/min: The usual dose should be administered every 24 hours.

CrCl 10-30 mL/min: The usual dose should be administered every 18 hours.

Liver Dose Adjustments

No adjustment recommended

Precautions

Sulfonamides should be given with caution to patients with impaired renal or hepatic function.

Dialysis

Peritoneal dialysis is not effective and hemodialysis is only moderately effective in eliminating Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops)

  • Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) Side Effects
  • During Pregnancy or Breastfeeding
  • Drug Images
  • Drug Interactions
  • Support Group
  • Drug class: sulfonamides

Related treatment guides

  • Bladder Infection
  • Bacterial Infection
  • Inclusion Conjunctivitis
  • Malaria
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Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) interactions

In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombopenia with purpura has been reported.

It has been reported that Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) may prolong the prothrombin time in patients who are receiving the anticoagulant warfarin. This interaction should be kept in mind when Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) is given to patients already on anticoagulant therapy, and the coagulation time should be reassessed.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) may inhibit the hepatic metabolism of phenytoin. At a 1.6-g dose, Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) produced a slight but significant increase in the half-life of phenytoin but did not produce a corresponding decrease in the metabolic clearance rate. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect.

Sulfonamides can also displace methotrexate from plasma protein-binding sites, thus increasing free methotrexate concentrations.

The presence of Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) may interfere with the Jaffé alkaline picrate reaction assay for creatinine, resulting in overestimations of about 10% in the range of normal values.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) side effects

Included in the listing that follows are adverse reactions that have not been reported with this specific drug; however, the pharmacologic similarities among the sulfonamides require that each of the reactions be considered with Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) (Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops)) administration.

Hematologic: Agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, hemolytic anemia, purpura, hypoprothrombinemia, methemoglobinemia, neutropenia, eosinophilia.

Allergic Reactions: Anaphylaxis, allergic myocarditis, serum sickness, conjunctival and scleral injection, generalized allergic reactions. In addition, periarteritis nodosa and systemic lupus erythematosus have been reported.

Dermatologic: Stevens-Johnson syndrome, epidermal necrolysis, erythema multiforme, exfoliative dermatitis, photosensitivity, pruritus, urticaria, rash, generalized skin eruptions.

Gastrointestinal: Hepatitis, hepatocellular necrosis, pseudomembranous enterocolitis, pancreatitis, stomatitis, glossitis, nausea, emesis, abdominal pain, diarrhea, anorexia.

Genitourinary:Creatinine elevation, toxic nephrosis with oliguria and anuria. The frequency of renal complications is considerably lower in patients receiving the more soluble sulfonamides.

Neurologic: Convulsions, peripheral neuritis, ataxia, vertigo, tinnitus, headache.

Psychiatric: Hallucinations, depression, apathy.

Endocrine: The sulfonamides bear certain chemical similarities to some goitrogens, diuretics (acetazolamide and the thiazides) and oral hypoglycemic agents. Cross-sensitivity may exist with these agents. Diuresis and hypoglycemia have occurred rarely in patients receiving sulfonamides.

Musculoskeletal: Arthralgia, myalgia.

Respiratory: Pulmonary infiltrates.

Miscellaneous: Edema (including periorbital), pyrexia, chills, weakness, fatigue, insomnia.

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) contraindications

Sulfamethoxazole sodium (Rohto Antibacterial Eye Drops) is contraindicated in individuals hypersensitive to trimethoprim and in those with documented megaloblastic anemia due to folate deficiency.

Active ingredient matches for Rohto Antibacterial Eye Drops:

- aminocaproic acid/chlorpheniramine maleate/Sulfamethoxazole sodium in Vietnam.


Unit description / dosage (Manufacturer)Price, USD
Rohto Antibacterial Eye Drops 1 Bottle 10 mL

List of Rohto Antibacterial Eye Drops substitutes (brand and generic names):

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "SULFAMETHOXAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "sulfamethoxazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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