Aceclofenac/paracetamol Uses

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Aceclofenac/paracetamol indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral

Pain and inflammation

Adult: Each tablet contains aceclofenac 100 mg and paracetamol 500 mg: 1 tablet in the morning and 1 tablet in the evening. Max: 2 tablets/day.

Aceclofenac/paracetamol description

Each film-coated tablet contains aceclofenac 100 mg, paracetamol 500 mg.

Aceclofenac/paracetamol dosage

Oral

Pain and inflammation

Adult: Each tablet contains aceclofenac 100 mg and paracetamol 500 mg: 1 tablet in the morning and 1 tablet in the evening. Max: 2 tablets/day.

Aceclofenac/paracetamol interactions

Paracetamol: Reduced absorption of cholestyramine within 1 hr of administration.

Accelerated absorption with metoclopramide.

Increased risk of liver damage in chronic alcoholics. Increased risk of toxicity with high doses or long term administration of barbiturates, carbamazepine, hydantoins, isoniazid, rifampicin and sulfinpyrazone.

Aceclofenac: May increase the plasma concentrations of lithium and digoxin.

Increased nephrotoxicity with diuretics. Serum-potassium should be monitored when used with potassium-sparing diuretics. May enhance activity of anticoagulants. May increase plasma methotrexate levels leading to toxicity if administered within 2-4 hours of methotrexate administration. Risk of convulsions with quinolones. Potentially fatal.

Aceclofenac/paracetamol side effects

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Paracetamol: Nausea, allergic reactions, skin rashes, acute renal tubular necrosis. Aceclofenac: Diarrhoea, headache, vertigo, dizzies, nervousness, tinnitus, depression, drowsiness, insomnia; fever, angioedema, bronchospasm, rashes; blood dyscrasias.

Potentially Fatal: Paracetamol: Very rare, blood dyscrasias (eg, thrombocytopaenia, leucopaenia, neutropaenia, agranulocytosis); liver damage. Aceclofenac: Severe GI bleeding; nephrotoxicity.

Aceclofenac/paracetamol contraindications

Aceclofenac/paracetamol is contraindicated in the following situations: Patients sensitive to Aceclofenac, Paracetamol or to any of the excipients of the product. Patients in whom aspirin or other Non-Steroidal Anti-Inflammatory Drug, precipitate attacks of bronchospasm, acute rhinitis or urticaria or patients hypersensitive to drugs. Patients with active or suspected peptic ulcer or gastrointestinal bleeding or bleeding disorders. Patients with severe heart failure, hypertension, hepatic or renal insufficiency. Third trimester of pregnancy.


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Active ingredient matches for Aceclofenac/paracetamol:

Aceclofenac/paracetamol


List of Aceclofenac/paracetamol substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
ACECLOFENAC + PARACETAMOL 1 strip / 10 tablets each (Jan Aushadhi)$ 0.23
ACECLOFLAM-P TABLET 1 strip / 10 tablets each (Knoll Pharmaceuticals Ltd)$ 0.87
ACECLOFLAM-P TABLET 1 strip / 15 tablets each (Knoll Pharmaceuticals Ltd)$ 1.24
10's (Nectar Lifesciences Ltd (Neccare))$ 0.71
Aceclogesic Plus 100+500 Tablet (Nectar Lifesciences Ltd (Neccare))$ 0.07
Aceclogesic Plus Aceclofenac 100 mg, Paracetamol 500 mg. TAB / 10 (Nectar Lifesciences Ltd (Neccare))$ 0.71
ACECLOGESIC PLUS tab 10's (Nectar Lifesciences Ltd (Neccare))$ 0.71
Aceclogesic Plus Aceclofenac 100 mg, Paracetamol 500 mg. TAB / 10 (Nectar Lifesciences Ltd (Neccare))$ 0.71
ACECLOGIP PLUS TABLET 1 strip / 10 tablets each (Gipla Healthcare)$ 0.53
ACECLOMAC PLUS 100MG/500MG TABLET 1 strip / 10 tablets each (Torque Pharmaceuticals Pvt Ltd)$ 0.15
ACECLOMAC PLUS 50MG/125MG SYRUP 1 bottle / 60 ML syrup each (Torque Pharmaceuticals Pvt Ltd)$ 0.63
Aceclomac Plus 100 mg/500 mg Tablet (Torque Pharmaceuticals Pvt Ltd)$ 0.01
Aceclomac Plus 50 mg/125 mg Syrup (Torque Pharmaceuticals Pvt Ltd)$ 0.63
Acecloren-P Aceclofenac 100mg, Paracetamol500mg TAB / 10$ 0.48
10's$ 0.48
Tablets; Oral; Aceclofenac 100 mg, Acetaminophen 500 mg
ACECLORITE PLUS 100 MG/500 MG TABLET 1 strip / 10 tablets each (MHS Pharmaceuticals Pvt Ltd)$ 0.46
ACEDAC-P tab 10's (Reliance Lifecare)$ 0.38
15's (Candor)$ 0.83
Acedase-P Aceclofenac 100mg, Paracetamol500mg TAB / 15 (Candor)$ 0.83
Tablets; Oral; Aceclofenac 100 mg, Acetaminophen 500 mg (Candor)
ACEDASE-P tab 15's (Candor)$ 0.83
Acedase-P Aceclofenac 100mg, Paracetamol500mg TAB / 15 (Candor)$ 0.83
Aceden-P Aceclofenac 100 mg, Paracetamol 500 mg TAB / 100 (BMW)$ 4.76
100's (BMW)$ 4.76
Tablets; Oral; Aceclofenac 100 mg, Acetaminophen 500 mg (BMW)
ACEDEN-P tab 10's (BMW)$ 0.48
ACEDEN-P syr 60ml (BMW)$ 0.62
ACEDIL 100MG/325MG TABLET 1 strip / 10 tablets each (Scott Edil Pharmacia Ltd)$ 0.90
ACEFAC P TABLET 1 strip / 15 tablets each (Tulip Lab Pvt Ltd)$ 0.71
Acefac P 100mg/325mg Tablet (Tulip Lab Pvt Ltd)$ 0.05
Acefen P 100+500 Tablet (Salud Care (I) Pvt. Ltd.)$ 0.05
ACEFEN P 100MG/500MG TABLET 1 strip / 10 tablets each (Salud Care (I) Pvt. Ltd.)$ 0.54
ACEFEN P 100MG/500MG TABLET 1 strip / 10 tablets each (Salud Care (I) Pvt. Ltd.)$ 0.45
Acefen P 100 mg/500 mg Tablet (Salud Care (I) Pvt. Ltd.)$ 0.05
Acefen-P Aceclofenac 100 mg, Paracetamol 500 mg TAB / 10 (Salud Care)$ 0.48
10's (Salud Care)$ 0.48
Tablets; Oral; Aceclofenac 100 mg, Acetaminophen 500 mg (Salud Care)
ACEFEN-P tab 10's (Salud Care)$ 0.48
ACEFEX-P 100 MG/325 MG TABLET 1 strip / 10 tablets each (Zydus Cadila)$ 0.18

References

  1. PubChem. "Aceclofenac". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Aceclofenac". http://www.drugbank.ca/drugs/DB06736 (accessed September 17, 2018).
  3. MeSH. "Anti-Inflammatory Agents, Non-Steroidal". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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