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Alizapride Dosage |
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Nausea and vomiting
Adult: 75-300 mg/day in divided doses.
Child: 5 mg/kg/day.
Nausea and vomiting associated with cancer chemotherapy
Adult: 2-5 mg/kg/day given by IV/IM in 2 divided doses. 1st dose to be administered 30 min before and the next dose 4-8 hr after admin of cytotoxic drug. For highly emetogenic regimens requiring doses >5 mg/kg, dose may be given via IV infusion over 15 min every 2 hr for 5 doses. Start infusion 30 min before admin of cytotoxic drug. Max: 4.5 g/course of chemotherapy.
• Levodopa: reciprocal antagonism of levodopa and neuroleptics.
• Combinations to Avoid
Alcohol: El alcohol potencializa el efecto sedante de Alizapride. Alcohol: Alcohol potentiates the sedative effect of Alizapride. Combinations to be taken into account: central nervous system depressants (neuroleptics, morphine derivatives, hypnotics, anxiolytics, sedative H1 antihistamines, antidepressants, sedatives, barbiturates, clonidine and congeners): the sedative effects of CNS depressants and Alizapride is maximized.
Anticholinergics: Concomitant administration may affect Alizapride effect.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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