Ambroxol Adipharm Uses

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Ambroxol Adipharm indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.

For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.

Uses of Ambroxol Adipharm in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Ambroxol Adipharm is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.

Ambroxol Adipharm description

Each retard capsule contains Ambroxol hydrochloride 75 mg.

Each tablet contains Ambroxol hydrochloride 30 mg.

Each 5 mL of syrup contains Ambroxol hydrochloride 15 or 30 mg.

Each mL of syrup (infant drops) contains Ambroxol hydrochloride 6 mg.

Ambroxol Adipharm hydrochloride is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.

It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.

Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.

Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.

Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.

Ambroxol Adipharm dosage

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Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Ambroxol Adipharm).

Ambroxol Adipharm SR capsule is not suitable for children <12 years.

Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.

Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.

DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.

Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.

Ambroxol Adipharm interactions

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Amoxicillin may decrease the effectiveness of contraceptives for oral administration.

With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.

Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.

Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.

Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.

Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.

With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.

Ambroxol Adipharm side effects

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Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.

Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).

With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.

Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.

Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.

Ambroxol Adipharm contraindications

Hypersensitivity to Ambroxol Adipharm hydrochloride or to any other excipients of Ambroxol Adipharm.

In case of rare hereditary conditions that may be incompatible with an excipient of Ambroxol Adipharm, the use of Ambroxol Adipharm is contraindicated.



Active ingredient matches for Ambroxol Adipharm:

Ambroxol in Bulgaria.


List of Ambroxol Adipharm substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Amcold SYR Cetirizine hydrochloride 5 mg, Ambroxol hydrochloride 30 mg. SYR / 100ml (Tablets)$ 0.48
100ml (Tablets)$ 0.48
AMCOLD SYR syr 100ml (Tablets)$ 0.48
Amelex 75 mg x 100's
Amgicol 30 mg
Amgicol 30 mg x Blister pk
Amlee-P Ambroxol hydrochloride 60 mg, Levocetirizine dihydrochloride5 mg, Pseudoephedrinehydrochloride 30 mg. TAB / 100 (Indkus)$ 8.57
100's (Indkus)$ 8.57
AMLEE-P tab 10's (Indkus)$ 0.86
Ampromed 30 mg x 1, 000's (Millimed)
Amriz Ambroxol hydrochloride, Terbutaline sulphate, Guaiphenesin, Menthol. SYR / 100ml (Ritz Pharma)$ 0.67
Amriz Ambroxol hydrochloride, Terbutaline sulphate, Guaiphenesin, Menthol. SYR / 60ml (Ritz Pharma)$ 0.44
100ml (Ritz Pharma)$ 0.67
60ml (Ritz Pharma)$ 0.44
AMRIZ syr 100ml (Ritz Pharma)$ 0.67

References

  1. PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
  3. MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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