Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
fast or pounding heartbeats;
swelling in your face, stomach, hands, or feet;
numbness, burning, pain, or tingly feeling;
feeling like you might pass out;
confusion, unusual thoughts or behavior;
pale skin, easy bruising;
painful or difficult urination;
dark-colored urine;
urinating less than usual or not at all; or
joint pain or swelling with fever, chest pain, weakness or tired feeling.
Less serious side effects may include:
nausea, vomiting, loss of appetite;
diarrhea, constipation;
headache;
dizziness;
anxiety;
muscle or joint pain;
runny or stuffy nose; or
mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Apresoline in details
A side effect of any drug can be defined as the unwanted or undesired effect produced by the drug. The side effect can be major or in few medications minor that can be ignored. Side effects not only vary from drug to drug, but it also depends on the dose of the drug, the individual sensitivity of the person, brand or company which manufactures it. If side effects overweigh the actual effect of the medicine, it may be difficult to convince the patient to take the drug. Few patients get specific side effects to specific drugs; in that case, a doctor replaces the drug with another. If you feel any side effect and it troubles you, do not forget to share with your healthcare practitioner.
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Applies to Apresoline: oral tablet
Other dosage forms:
injection solution
In addition to its needed effects, some unwanted effects may be caused by Apresoline (the active ingredient contained in Apresoline). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Apresoline:
More common:
Arm, back, or jaw pain
chest pain or discomfort
chest tightness or heaviness
fast, pounding, or irregular heartbeat or pulse
nausea
shortness of breath
sweating
Less common:
Black, tarry stools
blindness or vision changes
blisters on the skin
blurred vision
burning of the face or mouth
burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings
chills
clumsiness or unsteadiness
confusion
cough
difficult or labored breathing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fever and sore throat
general feeling of discomfort or illness or weakness
joint pain
lower back or side pain
muscle pain
numbness, tingling, pain, or weakness in the hands or feet
painful or difficult urination
pale skin
shakiness in the legs, arms, hands, or feet
skin rash or itching
swelling of the feet or lower legs
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
trembling or shaking of the hands or feet
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
weakness in hands or feet
Rare
Dark urine
light-colored stools
upper right abdominal or stomach pain
yellow eyes and skin
If any of the following symptoms of overdose occur while taking Apresoline, get emergency help immediately:
Symptoms of overdose:
Feeling of warmth
headache
redness of the face, neck, arms, and occasionally, upper chest
Minor Side Effects
Some of the side effects that can occur with Apresoline may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
More common:
Diarrhea
loss of appetite
weight loss
Less common:
Constipation
difficulty with moving
dizziness
feeling anxious or depressed
muscle cramps, pain, or stiffness
pain in the joints
rash, hives, welts, or itching
stuffy nose
watery eyes
What is the most important information I should know about Apresoline?
Apresoline injection may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Apresoline injection with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Apresoline injection may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Tell your doctor or dentist that you take Apresoline injection before you receive any medical or dental care, emergency care, or surgery.
Lab tests, including complete blood counts, blood pressure, and antinuclear antibody titers, may be performed while you use Apresoline injection. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Apresoline injection should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Apresoline injection, contact your doctor. You will need to discuss the benefits and risks of using Apresoline injection while pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you are using Apresoline injection, check with your doctor. Discuss any possible risks to your baby.
Apresoline contraindications
Contraindication can be described as a special circumstance or a disease or a condition wherein you are not supposed to use the drug or undergo particular treatment as it can harm the patient; at times, it can be dangerous and life threatening as well. When a procedure should not be combined with other procedure or when a medicine cannot be taken with another medicine, it is called Relative contraindication. Contraindications should be taken seriously as they are based on the relative clinical experience of health care providers or from proven research findings.
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You should not use this medication if you are allergic to Apresoline, or if you have coronary artery disease, or rheumatic heart disease affecting the mitral valve.
Before taking Apresoline, tell your doctor if you have kidney disease, lupus, angina pectoris (chest pain), or if you have ever had a stroke.
While taking Apresoline, avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Call your doctor at once if you have a serious side effect such as fast or pounding heartbeats, swelling, numbness or tingling, dark-colored urine, joint pain or swelling with fever, chest pain, weakness or tired feeling, and urinating less than usual or not at all.
To be sure this medication is helping your condition and is not causing harmful effects, your blood pressure will need to be checked often. You may also need occasional blood tests. Do not miss any scheduled appointments.
Keep using Apresoline as directed, even if you feel well. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.
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References
DTP/NCI. "hydralazine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
European Chemicals Agency - ECHA. "hydralazine: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Apresoline are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Apresoline. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
User reports
Consumer reported side effects
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