Aztreonam Vitalis Pregnancy

• Pregnancy of Aztreonam Vitalis in details
• Aztreonam Vitalis breastfeeding
• Aztreonam Vitalis reviews

Pregnancy of Aztreonam Vitalis in details

Aztreonam Vitalis crosses the placenta and reaches the fetal circulation following IV administration; however, peak plasma concentrations following inhalation of Aztreonam Vitalis are significantly less than those observed following Aztreonam Vitalis IV.

Due to its poor systemic absorption, use of Aztreonam Vitalis inhalation is likely acceptable for the management of cystic fibrosis in pregnant patients with Pseudomonas aeruginosa (Kroon 2018; Middleton 2019). When required, use may continue during pregnancy (Middleton 2019).

Aztreonam Vitalis breastfeeding

Aztreonam Vitalis is excreted into human milk in small amounts that are less than 1% of maternal serum concentrations. Systemic effects in the infant are considered unlikely. Aztreonam Vitalis is considered compatible with breast-feeding by the American Academy of Pediatrics.

See references

References for pregnancy information

1. "Product Information. Azactam (Aztreonam Vitalis)." Bristol-Myers Squibb, Princeton, NJ.
2. "Product Information. Cayston (Aztreonam Vitalis)." Gilead Sciences, Foster City, CA.

References for breastfeeding information

1. Committee on Drugs, 1992 to 1993 "The transfer of drugs and other chemicals into human milk." Pediatrics 93 (1994): 137-50
2. Fleiss PM, Richwald GA, Gordon J, et al "Aztreonam Vitalis in human serum and breast milk." Br J Clin Pharmacol 19 (1985): 509-11
3. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
4. "Product Information. Cayston (Aztreonam Vitalis)." Gilead Sciences, Foster City, CA.
5. "Product Information. Azactam (Aztreonam Vitalis)." Bristol-Myers Squibb, Princeton, NJ.

References

1. DailyMed. "AZTREONAM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubMed Health. "Aztreonam (By breathing): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
3. Human Metabolome Database (HMDB). "Aztreonam: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology