Beclometasone Topical Overdose

How do you administer this medicine?
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What happens if I overdose Beclometasone Topical?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of beclomethasone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

Overdose of Beclometasone Topical in details

When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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When used at excessive doses, systemic corticosteroid effects eg, hypercorticism and adrenal suppression may occur. If such changes occur, Beclometasone Topical should be discontinued slowly, consistent with acceptable procedures of discontinuing oral steroid therapy. The acute toxicity of beclomethasone dipropionate is low.

What should I avoid while taking Beclometasone Topical?

Avoid getting this medication in your eyes. If this does happen, rinse with water and call your doctor.

Beclomethasone nasal can lower the blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using beclomethasone nasal.

Beclometasone Topical warnings

Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.

The replacement of a systemic corticosteroid with beclomethasone dipropionate nasal inhaler or spray can be accompanied by signs of adrenal insufficiency.

Careful attention must be given when patients previously treated for prolonged periods with systemic corticosteroids are transferred to beclomethasone dipropionate nasal inhaler or spray. This is particularly important in those patients who have associated asthma or other clinical conditions where too rapid a decrease in systemic corticosteroids may cause a severe exacerbation of their symptoms.

Studies have shown that combined administration of alternate-day prednisone systemic treatment and orally inhaled beclomethasone dipropionate increases the likelihood of HPA suppression compared to a therapeutic dose of either one alone. Therefore, nasal forms of beclomethasone dipropionate should be used with caution in patients already on alternate day prednisone regimens for any disease.

If recommended doses of intranasal beclomethasone are exceeded or if individuals are particularly sensitive or predisposed by virtue of recent systemic steroid therapy, symptoms of hypercorticism may occur, including very rare cases of menstrual irregularities, acneform lesions, cataracts, and cushingoid features. If such changes occur, this drug should be discontinued slowly consistent with accepted procedures for discontinuing oral steroid therapy.

Persons who are on drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in nonimmune children or adults on corticosteroids. In such children or adults who have not had these diseases, particular care should be taken to avoid exposure of these infectious agents. How the dose, route, and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk of developing a more severe infection is also not known. If exposed to chickenpox, prophylaxis with varicella zoster immune globulin (VZIG) may be indicated. If exposed to measles, prophylaxis with pooled intramuscualr immunoglobulin (IG), may be indicated. If chickenpox develops, treatment with antiviral agents may be considered.

What should I discuss with my healthcare provider before taking Beclometasone Topical?

You should not use this medication if you are allergic to beclomethasone.

Before using beclomethasone, tell your doctor if you have been sick or have had an infection of any kind. You may not be able to use beclomethasone nasal until you are well.

To make sure you can safely use beclomethasone, tell your doctor if you have any of these other conditions:

FDA pregnancy category C. It is not known whether beclomethasone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether beclomethasone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Steroid medicines can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using beclomethasone nasal.

Beclometasone Topical should not be given to a child younger than 6 years old. Qnasl should not be given to a child younger than 12 years old.

Beclometasone Topical precautions

Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Patients suffering from tuberculosis should be treated with care. Sinusitis may be treated properly.

Patients should be taught the proper use of Beclometasone Topical to ensure the good clinical efficacy. They should also be aware that Beclometasone Topical has to be used regularly for optimal benefit. Patients should be advised that Beclometasone Topical will not provide immediate symptomatic relief and use of topical nasal decongestant or oral antihistamines may be necessary until the effects of intranasal beclomethasone dipropionate are fully manifested. Infections of the nasal passages and paranasal sinuses should be appropriately treated but do not constitute a specific contraindication to treatment with Beclometasone Topical.

Care must be taken while transferring patients from systemic steroid treatment to Beclometasone Topical if there is any reason to suppose that their adrenal function is impaired.

A heavy challenge of summer allergens may, in certain instances, necessitate appropriate additional therapy, particularly to control eye symptoms.

In the continuous long-term treatment with intranasal steroids, the nasal mucosa should be inspected regularly, at least once a year. Intranasal corticosteroid should be used with caution until healing occurs in patients with recent nasal septal ulcers, nasal surgery or nasal trauma, since the drug may inhibit wound healing.

Use in pregnancy & lactation: Administration of corticosteroids to pregnant animals can cause abnormalities of fetal development, including cleft palate and intrauterine growth retardation. There may therefore be a very small risk of such effects in the human fetus. It should be noted, however, that the fetal changes in animals occur after relatively high systemic exposure; direct; intranasal application ensures minimal systemic exposure.

The use of beclomethasone dipropionate during pregnancy requires the possible benefits of Beclometasone Topical be weighed against the possible hazards. It should be noted that the drug has been in widespread use for many years without apparent ill consequence.

The use of beclomethasone dipropionate in mothers breastfeeding their babies requires that the therapeutic benefits of Beclometasone Topical be weighed against the potential hazard to the mother and baby.

Use in children: Use of Beclometasone Topical is not recommended for children <6 years.

Controlled clinical studies have shown that intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients. This effect has been observed in the absence of laboratory evidence of hypothalamic-pituitary-adrenal (HPA) axis suppression, suggesting that growth velocity is a more sensitive indicator or systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis function. The long-term effects of this reduction in growth velocity associated with intranasal corticosteroids, including the impact on final adult height, are unknown. The potential for "catch up" growth following discontinuation of treatment with intranasal corticosteroids has not been adequately studied. The growth of pediatric patients receiving intranasal corticosteroids should be monitored routinely (eg, via stadiometry). The potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of safe and effective noncorticosteroid treatment alternatives. To minimize the systemic effects of intranasal corticosteroids, each patient should be titrated to his/her lowest effective dose.

What happens if I miss a dose of Beclometasone Topical?

When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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