Beclometasone Topical/Clotrimazole Topical/Neomycin Topical Pregnancy

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Consists of Beclometasone Topical, Clotrimazole Topical, Neomycin Topical

Pregnancy of Beclometasone Topical in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Pregnancy of Clotrimazole Topical in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.

Clotrimazole topical has been assigned to pregnancy category B by the FDA. Systemic absorption is minimal following topical or vaginal administration. Animals given high doses intravaginally have not revealed evidence of teratogenicity. High oral doses resulted in embryotoxicity and maternal toxicity. In clinical trials involving women in their second and third trimester, clotrimazole treatment of vaginal candidiasis was not associated with fetal harm. Clotrimazole use has not been well studied during the first trimester. Clotrimazole should only be used during the first trimester when need has been clearly established.

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Clotrimazole Topical breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

There are no data on the excretion of clotrimazole into human milk. However, systemic absorption is minimal after topical and vaginal administration. The manufacturer recommends that caution be used when administering clotrimazole topical to nursing women.

See references

References for pregnancy information

  1. "Product Information. Mycelex (clotrimazole)." Bayer, West Haven, CT.
  2. Tan CG, Good CS, Milne LJ, Loudon JD "A comparative trial of six day therapy with clotrimazole and nystatin in pregnant patients with vaginal candidiasis." Postgrad Med J 50 Suppl 1 (1974): 102-5
  3. Haram K, Digranes A "Vulvovaginal candidiasis in pregnancy treated with clotrimazole." Acta Obstet Gynecol Scand 57 (1978): 453-5
  4. Lindeque BG, van Niekerk WA "Treatment of vaginal candidiasis in pregnancy with a single clotrimazole 500 mg vaginal pessary." S Afr Med J 65 (1984): 123-4
  5. "Product Information. Lotrimin (clotrimazole topical)." Schering-Plough Corporation, Kenilworth, NJ.
  6. Frerich W, Gad A "The frequency of Candida infections in pregnancy and their treatment with clotrimazole." Curr Med Res Opin 4 (1977): 640-4

References for breastfeeding information

  1. "Product Information. Lotrimin (clotrimazole topical)." Schering-Plough Corporation, Kenilworth, NJ.

Pregnancy of Neomycin Topical in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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The manufacturer makes no recommendation regarding use during pregnancy. US FDA pregnancy category: Not formally assigned to a pregnancy category.

Animal studies have not been reported. There are no controlled data in human pregnancy.

See references

Neomycin Topical breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

The manufacturer makes no recommendation regarding use during lactation. Excreted into human milk: Data not available Excreted into animal milk: Data not available Comments: -The effects in the nursing infant are unknown; negligible risk is expected, however, topical application to the nipple may increase risk for diarrhea in the infant. -Ointments should not be applied to the breast prior to breastfeeding; water miscible cream or gel products should be used if necessary.

See references

References for pregnancy information

  1. "Product Information. Myciguent (neomycin topical)." Pharmacia and Upjohn, Kalamazoo, MI.
  2. Cerner Multum, Inc "Malaysia product information." O 0 (2015):

References for breastfeeding information

  1. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
  2. "Product Information. Myciguent (neomycin topical)." Pharmacia and Upjohn, Kalamazoo, MI.
  3. Cerner Multum, Inc "Malaysia product information." O 0 (2015):


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References

  1. DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "BETAMETHASONE DIPROPIONATE; CLOTRIMAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubMed Health. "Neomycin (Ophthalmic route): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).

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