Bendaz Uses

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What is Bendaz?

Bendaz is used to treat neurocysticercosis, an infection of the nervous system caused by pork tapeworms. Bendaz is also used to treat cystic hydatid disease of the liver, lung, and peritoneum, an infection caused by dog tapeworms.

Bendaz is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies.

Bendaz is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling in the U.S., Bendaz is used in certain patients with the following infections:

For patients taking Bendaz for hookworms:

For patients taking Bendaz for pinworms:

Bendaz indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Neurocysticercosis

Bendaz tablets are indicated for the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium.

Hydatid Disease

Bendaz tablets are indicated for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.

How should I use Bendaz?

Use Bendaz as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Bendaz.

Uses of Bendaz in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Use: Labeled Indications

Hydatid disease (Echinococcus granulosus, dog tapeworm): Treatment of cystic hydatid disease of the liver, lung, and peritoneum caused by the larval form of the dog tapeworm, E. granulosus.

Neurocysticercosis (Taenia solium, pork tapeworm), parenchymal disease: Treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, T. solium.

Off Label Uses

Ancylostoma caninum (eosinophilic enterocolitis)

Clinical experience suggests the utility of Bendaz in the treatment of Ancylostoma caninum .

Bendaz description

Bendaz is a molecule containing the sulfonamide functional group attached to an aniline.

Bendaz dosage

Dosage

Dosing of Bendaz tablets will vary depending upon the indication. Bendaz tablets may be crushed or chewed and swallowed with a drink of water. Bendaz tablets should be taken with food.

Table 1: Bendaz Tablets Dosage
Indication

Patient Weight

Dose

Duration

Hydatid Disease

60 kg or greater

400 mg twice daily, with meals

28-day cycle followed by a 14-day Bendaz-free interval, for a total of 3 cycles

Less than 60 kg

15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)

Neurocysticercosis

60 kg or greater

400 mg twice daily, with meals

8 to 30 days

Less than 60 kg

15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)

Concomitant Medication to Avoid Adverse Reactions

Patients being treated for neurocysticercosis should receive appropriate steroid and anticonvulsant therapy as required.

Oral or intravenous corticosteroids should be considered to prevent cerebral hypertensive episodes during the first week of treatment.

Monitoring for Safety Before and During Treatment

Bendaz interactions

See also:
What other drugs will affect Bendaz?

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Dexamethasone: Steady-state trough concentrations of Bendaz sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of Bendaz (15 mg/kg/day) in eight neurocysticercosis patients.

Praziquantel: In the fed state, praziquantel (40 mg/kg) increased mean maximum plasma concentration and area under the curve of Bendaz sulfoxide by about 50% in healthy subjects (n=10) compared with a separate group of subjects (n=6) given Bendaz alone. Mean T max and mean plasma elimination half-life of Bendaz sulfoxide were unchanged. The pharmacokinetics of praziquantel were unchanged following coadministration with Bendaz (400 mg).

Cimetidine: Bendaz sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n=7) compared with Bendaz (20 mg/kg/day) alone (n=12). Bendaz sulfoxide plasma concentrations were unchanged 4 hours after dosing.

Theophylline: The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of Bendaz (400 mg) in 6 healthy subjects.

Bendaz side effects

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What are the possible side effects of Bendaz?

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Applies to Bendaz: oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Bendaz. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Bendaz:

Less common:

Rare Incidence not known:

Minor Side Effects

Some of the side effects that can occur with Bendaz may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

Less common: Less common or rare: Incidence not known:

Bendaz contraindications

See also:
What is the most important information I should know about Bendaz?

Bendaz tablets are contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of Bendaz tablets.

Active ingredient matches for Bendaz:

Albendazole


Unit description / dosage (Manufacturer)Price, USD
Bendaz 10 ml Suspension$ 0.12

List of Bendaz substitutes (brand and generic names):

Bendazol 50 mg
Benden 400mg TAB / 1 (Systemic)
Benden 200mg SYR / 10ml (Systemic)
BENDEN tab 400 mg x 10's (Systemic)
BENDEN syr 200 mg x 10ml (Systemic)
Bender 200mg/5ml Suspension (Tusker Pharma Pvt Ltd)$ 0.35
BENDEX Liquid / 200mg per 5ml / 10ml units (Cipla Limited)$ 0.31
BENDEX Capsule/ Tablet / 400mg / 1 units (Cipla Limited)$ 0.22
Bendex 400mg TAB / 1 (Cipla Limited)$ 0.25
Bendex 200mg x 5mL SUSP / 10ml (Cipla Limited)$ 0.36
400 mg x 1's (Cipla Limited)$ 0.25
200 mg x 5 mL x 10ml (Cipla Limited)$ 0.36
Bendex 400 mg Tablet (Cipla Limited)$ 0.22
Bendex 10 ml Suspension (Cipla Limited)$ 0.14
BENDEX 200 MG SUSPENSION 1 bottle / 10 suspensions each (Cipla Limited)$ 0.26
BENDEX 400 MG SYRUP 1 bottle / 15 ML syrup each (Cipla Limited)$ 0.37
BENDEX 400 MG TABLET 1 strip / 1 tablet each (Cipla Limited)$ 0.16
BENDEX chewable tab 400 mg x 1's (Cipla Limited)$ 0.15
BENDEX oral susp 200 mg x 5 mL x 10ml (Cipla Limited)$ 0.25
Bendex 200mg Suspension (Cipla Limited)$ 0.26
Bendex 400mg Syrup (Cipla Limited)$ 0.37
Bendex 400mg Tablet (Cipla Limited)$ 0.12
Bendifer 400mg TAB / 2 (Biophar)$ 0.29
BENDIFER tab 400 mg x 2's (Biophar)$ 0.29
Bendross 400mg Tablet (Emami Frank Ross Ltd)$ 0.12
Bendtus 400mg Tablet (Tusker Pharma Pvt Ltd)$ 0.06
Bendup 400 mg Tablet (UPS Healthcare)$ 0.13
Bendup 10 ml Suspension (UPS Healthcare)$ 0.11
Beniver Albendazole 400 mg, Ivermectin6 mg TAB / 1 (Medihealth)
1's (Medihealth)
Beniver Albendazole 400 mg, ivermectin6 mg. TAB / 1 (Medihealth)
BENIVER tab 1's (Medihealth)
Benkem 10 ml Suspension (Anikem Laboratories)$ 0.17
Benkem 400 mg Tablet (Anikem Laboratories)$ 0.17
Benle 400 mg Tablet (Blue Star Laboratories Pvt Ltd)$ 0.02
Benmax 400 mg Tablet (Biomax Laboratories)$ 0.19
Benmax 10 ml Suspension (Biomax Laboratories)$ 0.12
BENPLUS 200MG SYRUP 1 bottle / 10 ML syrup each (Torque Pharmaceuticals Pvt Ltd)$ 0.12

References

  1. DailyMed. "ALBENDAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "albendazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "albendazole". http://www.drugbank.ca/drugs/DB00518 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Bendaz are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Bendaz. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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1 consumer reported age

Users%
16-291
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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