Bendex is used to treat neurocysticercosis, an infection of the nervous system caused by pork tapeworms. Bendex is also used to treat cystic hydatid disease of the liver, lung, and peritoneum, an infection caused by dog tapeworms.
Bendex is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies.
Bendex is available only with your doctor's prescription.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling in the U.S., Bendex is used in certain patients with the following infections:
Capillariasis.
Cutaneous larva migrans.
Common roundworms (ascariasis).
Hookworms (ancylostomiasis and necatoriasis).
Pinworms (enterobiasis or oxyuriasis).
Strongyloidiasis.
Tapeworms (taeniasis).
Trichostrongyliasis.
Whipworms (trichuriasis).
For patients taking Bendex for hookworms:
In hookworm infections, anemia may occur. Therefore, your doctor may want you to take iron supplements. If so, it is important to take iron every day while you are being treated for hookworm infection. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for at least 3 to 6 months after you stop taking Bendex. If you have any questions about this, check with your doctor.
For patients taking Bendex for pinworms:
In some patients, pinworms may return after treatment with Bendex. Wear pajamas and underwear to sleep, take a bath every day, and wash (not shake) all bedding and nightclothes (pajamas) after treatment to help prevent reinfection. Treatment may be repeated after 3 weeks.
Pinworms may be easily passed from one person to another, especially among persons in the same household. Therefore, all household members may have to be treated at the same time to prevent their infection or reinfection.
Bendex indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Neurocysticercosis
Bendex tablets are indicated for the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium.
Hydatid Disease
Bendex tablets are indicated for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
How should I use Bendex?
Use Bendex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Bendex by mouth with food.
If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water.
If you miss a dose of Bendex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.
Ask your health care provider any questions you may have about how to use Bendex.
Uses of Bendex in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Use: Labeled Indications
Hydatid disease (Echinococcus granulosus, dog tapeworm): Treatment of cystic hydatid disease of the liver, lung, and peritoneum caused by the larval form of the dog tapeworm, E. granulosus.
Neurocysticercosis (Taenia solium, pork tapeworm), parenchymal disease: Treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, T. solium.
Off Label Uses
Ancylostoma caninum (eosinophilic enterocolitis)
Clinical experience suggests the utility of Bendex in the treatment of Ancylostoma caninum .
Bendex description
Bendex is a molecule containing the sulfonamide functional group attached to an aniline.
Bendex dosage
Dosage
Dosing of Bendex tablets will vary depending upon the indication. Bendex tablets may be crushed or chewed and swallowed with a drink of water. Bendex tablets should be taken with food.
Table 1: Bendex Tablets Dosage
Indication
Patient Weight
Dose
Duration
Hydatid Disease
60 kg or greater
400 mg twice daily, with meals
28-day cycle followed by a 14-day Bendex-free interval, for a total of 3 cycles
Less than 60 kg
15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)
Neurocysticercosis
60 kg or greater
400 mg twice daily, with meals
8 to 30 days
Less than 60 kg
15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)
Concomitant Medication to Avoid Adverse Reactions
Patients being treated for neurocysticercosis should receive appropriate steroid and anticonvulsant therapy as required.
Oral or intravenous corticosteroids should be considered to prevent cerebral hypertensive episodes during the first week of treatment.
Monitoring for Safety Before and During Treatment
Monitor blood counts at the beginning of each 28-day cycle of therapy, and every 2 weeks while on therapy with Bendex tablets in all patients.
Monitor liver enzymes (transaminases) at the beginning of each 28-day cycle of therapy, and at least every 2 weeks during treatment with Bendex tablets in all patients.
Obtain a pregnancy test in women of reproductive potential prior to therapy.
Dexamethasone: Steady-state trough concentrations of Bendex sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of Bendex (15 mg/kg/day) in eight neurocysticercosis patients.
Praziquantel: In the fed state, praziquantel (40 mg/kg) increased mean maximum plasma concentration and area under the curve of Bendex sulfoxide by about 50% in healthy subjects (n=10) compared with a separate group of subjects (n=6) given Bendex alone. Mean T max and mean plasma elimination half-life of Bendex sulfoxide were unchanged. The pharmacokinetics of praziquantel were unchanged following coadministration with Bendex (400 mg).
Cimetidine: Bendex sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n=7) compared with Bendex (20 mg/kg/day) alone (n=12). Bendex sulfoxide plasma concentrations were unchanged 4 hours after dosing.
Theophylline: The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of Bendex (400 mg) in 6 healthy subjects.
Applies to Bendex: oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Bendex. In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Bendex:
Less common:
Fever
Rare
Black, tarry stools
bleeding gums
blood in the urine or stools
chest pain
chills
cough
painful or difficult urination
pinpoint red spots on the skin
shortness of breath
sore throat
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
Incidence not known:
Blistering, peeling, loosening of the skin
blurred vision
dark-colored urine
diarrhea
general feeling of tiredness or weakness
headache
itching
joint or muscle pain
light-colored stools
red, irritated eyes
seizures
stomach pain, continuing
tightness in the chest
vomiting
yellow eyes or skin
Minor Side Effects
Some of the side effects that can occur with Bendex may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Bendex tablets are contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of Bendex tablets.
DailyMed. "ALBENDAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Bendex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Bendex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
User reports
Consumer reported useful
No survey data has been collected yet
Consumer reported price estimates
No survey data has been collected yet
2 consumers reported time for results
To what extent do I have to use Bendex before I begin to see changes in my health conditions? As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions. Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Bendex. To get the time effectiveness of using Bendex drug by other patients, please click here.
Users
%
1 day
1
50.0%
2 days
1
50.0%
2 consumers reported age
Users
%
1-5
2
100.0%
Consumer reviews
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