Benoquin Uses

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Benoquin indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Benoquin Cream 20% is indicated for final depigmentation in extensive Vitiligo.

Benoquin Cream 20% is applied topically to permanently depigment normal skin surrounding vitiliginous lesions in patients with disseminated (greater than 50 percent of body surface area) idiopathic vitiligo.

Benoquin Cream 20% is not recommended in freckling; hyperpigmentation caused by photosensitization following the use of certain perfumes (berlock dermatitis); melasma (chloasma) of pregnancy; or hyperpigmentation resulting from inflammation of the skin. Benoquin Cream 20% is not effective for the treatment of cafe-au-lait spots, pigmented nevi, malignant melanoma or pigmentation resulting from pigments other than melanin (e.g.: bile, silver, or artificial pigments).

Benoquin description

Benoquin is the monobenzyl ether of hydroquinone used medically for depigmentation. Benoquin occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. The topical application of Benoquin in animals increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Benoquin may cause destruction of melanocytes and permanent depigmentation.

Benoquin dosage


Benoquin Dosage

Generic name: Benoquin

Dosage form: cream, USP

The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.

A thin layer of Benoquin Cream 20% should be applied and rubbed into the pigmented area two or three times daily, or as directed by physician. Prolonged exposure to sunlight should be avoided during treatment with Benoquin Cream 20%, or a sunscreen should be used.

Depigmentation is usually accomplished after one to four months of Benoquin Cream 20% treatment. If satisfactory results are not obtained after four months of Benoquin Cream 20% treatment, the drug should be discontinued. When the desired degree of depigmentation is obtained, Benoquin Cream 20% should be applied only as often as needed to maintain depigmentation (usually only two times weekly).

More about Benoquin (Benoquin topical)

Professional resources

Benoquin interactions


Possible food and drug interactions when taking Benoquin disodium

While drug interactions with Benoquin disodium have not yet been studied, it is possible that oral antibiotics could interfere with the release of Benoquin disodium in the colon.

Benoquin side effects

Mild, transient skin irritation and sensitization, including erythematous and eczematous reactions have occurred following topical application of Benoquin Cream 20%. Although those reactions are usually transient, treatment with Benoquin Cream 20% should be discontinued if irritation, a burning sensation, or dermatitis occur. Areas of normal skin distant to the site of Benoquin Cream 20% application frequently have become depigmented, and irregular, excessive, unsightly, and frequently permanent depigmentation has occurred.

Benoquin contraindications

Benoquin Cream 20% contains a potent depigmenting agent and is not a cosmetic skin bleach. Use of Benoquin Cream 20% is contraindicated in any conditions other than disseminated vitiligo. Benoquin Cream 20% frequently produces irreversible depigmentation, and it must not be used as a substitute for hydroquinone.

Benoquin Cream 20% is also contraindicated in individuals with a history of sensitivity or allergic reactions to this product, or any of its ingredients.

Active ingredient matches for Benoquin:

Monobenzone in Argentina, India.

Balsalazide in Argentina.

Unit description / dosage (Manufacturer)Price, USD
Cream; Topical; Monobenzone 20%
35.4 gram in 1 tube
Benoquin Skin 20 gm Ointment$ 0.51
Benoquin 20% OINT / 20g$ 0.51

List of Benoquin substitutes (brand and generic names):

20 % x 20g (Mac)$ 0.51
Benoquin Oint 20% OINT / 20g (Mac)$ 0.51
BENOQUIN OINT oint 20 % x 20g (Mac)$ 0.51
Benoquin Oint 20% OINT / 20g (Mac)$ 0.51
BENOQUIN OINT. Cream/ Gel/ Ointment / 0.2 / 20gm units (Mac Laboratories)$ 0.48
Capsule; Oral; Balsalazide Sodium 750 mg (Astrazeneca)
Colorex 750mg CAP / 10 (Rexcel (Ranbaxy Laboratories Ltd))$ 1.73
Colorex - SYR / 100ml (Rexcel (Ranbaxy Laboratories Ltd))$ 0.51
750 mg x 10's (Rexcel (Ranbaxy Laboratories Ltd))$ 1.73
100ml (Rexcel (Ranbaxy Laboratories Ltd))$ 0.51
Colorex 750 mg Capsule (Rexcel (Ranbaxy Laboratories Ltd))$ 0.17
COLOREX 750 MG CAPSULE 1 strip / 10 capsules each (Rexcel (Ranbaxy Laboratories Ltd))$ 1.73
COLOREX cap 750 mg x 10's (Rexcel (Ranbaxy Laboratories Ltd))$ 1.73
COLOREX syr 100ml (Rexcel (Ranbaxy Laboratories Ltd))$ 0.51
Cozabal 750mg CAP / 10 (Sun Pharmaceutical Industries Ltd.)$ 1.43
750 mg x 10's (Sun Pharmaceutical Industries Ltd.)$ 1.43
Cozabal 750 mg Capsule (Sun Pharmaceutical Industries Ltd.)$ 0.14
COZABAL 750MG TABLET 1 strip / 10 tablets each (Sun Pharmaceutical Industries Ltd.)$ 1.43
COZABAL cap 750 mg x 10's (Sun Pharmaceutical Industries Ltd.)$ 1.43
Cozabal 750mg Tablet (Sun Pharmaceutical Industries Ltd.)$ 0.14
Giazo tablet, film coated 1.1 g/1 (Salix Pharmaceuticals, Inc (US))
750 mg x 10's (Arron (Intas Pharmaceuticals Ltd.))$ 1.41
Intazide 750mg CAP / 10 (Arron (Intas Pharmaceuticals Ltd.))$ 1.41
Intazide 750 mg Capsule (Arron (Intas Pharmaceuticals Ltd.))$ 0.15
INTAZIDE 750 MG CAPSULE 1 strip / 10 capsules each (Arron (Intas Pharmaceuticals Ltd.))$ 2.17
INTAZIDE cap 750 mg x 10's (Arron (Intas Pharmaceuticals Ltd.))$ 1.41
Hydroquinone mono benzyl ether (Vis)$ 5.28
Ointment; Ophthalmic; Prednisolone Acetate 10%; Sulfacetamide Sodium 0.45% (Grin)
Suspension; Ophthalmic; Prednisolone Acetate 10%; Sulfacetamide Sodium 0.45% (Grin)


  1. DailyMed. "BALSALAZIDE DISODIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed September 17, 2018).
  2. PubChem. "BALSALAZIDE". (accessed September 17, 2018).
  3. DrugBank. "BALSALAZIDE". (accessed September 17, 2018).


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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