Consists of betamethasone dipropionate, gentamicin sulfate, miconazole nitrate
What is Betamethasone dipropionate?
Betamethasone dipropionate topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. Betamethasone dipropionate dipropionate is a corticosteroid (cortisone-like medicine or steroid).
Betamethasone dipropionate dipropionate is available only with your doctor's prescription.
Betamethasone dipropionate indications
Betamethasone dipropionate dipropionate gel (augmented) is a super-high potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Treatment beyond two consecutive weeks is not recommended, and the total dose should not exceed 50 g per week because of potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.
This product is not recommended for use in pediatric patients under 12 years of age.
How should I use Betamethasone dipropionate?
Use Betamethasone dipropionate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Shake well before each use.
- Place nozzle of the bottle very close to the affected area and gently squeeze a small amount of medicine onto the affected area. Do not touch the nozzle to the skin. Gently rub the medicine in until it is evenly distributed. Wash your hands after applying Betamethasone dipropionate, unless your hands are part of the treated area. Do not apply Betamethasone dipropionate to the face, groin, or armpit unless otherwise directed by your doctor.
- Do not cover the treating area with bandages, wrappings, or other dressings unless advised to do so by your health care provider.
- If you miss a dose of Betamethasone dipropionate, apply it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Betamethasone dipropionate.
Uses of Betamethasone dipropionate in details
Betamethasone dipropionate is used to treat allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, and bronchial asthma
Topical preparations of Betamethasone dipropionate are used to treat skin problems like eczema (a type of itchy skin rash), atopic dermatitis (inflammation of skin) and psoriasis of the scalp, hands and feet.
Betamethasone dipropionate description
Each gram of Betamethasone dipropionate (Betamethasone dipropionate*) Cream* contains: 640 mcg Betamethasone dipropionate dipropionate (equivalent to 500 mcg Betamethasone dipropionate).
Each gram of Betamethasone dipropionate (Betamethasone dipropionate*) Ointment* contains: 640 mcg Betamethasone dipropionate dipropionate (equivalent to 500 mcg Betamethasone dipropionate).
Betamethasone dipropionate (Betamethasone dipropionate*) Cream and Ointment contain Betamethasone dipropionate dipropionate, a synthetic corticosteroid with anti-inflammatory activity to be administered topically.
Betamethasone dipropionate dipropionate is a white to creamy white odorless crystalline powder insoluble in water; freely soluble in acetone and in chloroform; sparingly soluble in alcohol. It has a molecular weight of 504.16 and the empirical formula C28H37FO7; a chemical name of 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione,17,21-dipropionate.
Betamethasone dipropionate dosage
Apply a thin film of Betamethasone dipropionate, 0.5% (augmented) to the affected skin areas once or twice daily. Therapy should be discontinued when control is achieved. Betamethasone dipropionate, 0.5% (augmented)is a high-potency corticosteroid. Treatment with Betamethasone dipropionate, 0.5% (augmented)should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.
Betamethasone dipropionate, 0.5% (augmented)should not be used with occlusive dressings unless directed by a physician.
Betamethasone dipropionate, 0.5% (augmented)is for topical use only. It is not for oral, ophthalmic, or intravaginal use.
Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.
Betamethasone dipropionate interactions
See also:
What other drugs will affect Betamethasone dipropionate?
There are no known drug interactions with topical Betamethasone dipropionate dipropionate.
Betamethasone dipropionate side effects
See also:
What are the possible side effects of Betamethasone dipropionate?
Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
In controlled clinical trials, involving 242 adult subjects, the adverse reaction associated with the use of Betamethasone dipropionate, 0.5% (augmented)reported at a frequency of 0.4% was stinging. It occurred in 1 subject.
In a controlled clinical trial involving 67 pediatric subjects from 3 months to 12 years of age, the adverse reactions associated with the use of Betamethasone dipropionate, 0.5% (augmented)occurred in 7 of 67 (10%) subjects. Reported reactions included signs of skin atrophy (telangiectasia, bruising, shininess).
Postmarketing Experience
Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Postmarketing reports for local adverse reactions to topical corticosteroids may also include: burning, itching, irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, hypertrichosis, skin atrophy, striae, and miliaria.
Hypersensitivity reactions, consisting of predominantly skin signs and symptoms, e.g., contact dermatitis, pruritus, bullous dermatitis, and erythematous rash have been reported.
Betamethasone dipropionate contraindications
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What is the most important information I should know about Betamethasone dipropionate?
Betamethasone dipropionate, 0.5% (augmented)is contraindicated in patients who are hypersensitive to Betamethasone dipropionate Dipropionate, to other corticosteroids, or to any ingredient in this preparation.
What is Gentamicin sulfate?
Treating surface eye infections caused by certain bacteria.
Gentamicin sulfate is a topical antibiotic. It works by slowing the growth of, or killing, sensitive bacteria.
Gentamicin sulfate indications
Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum. Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial superinfections of fungal or viral infections. Please Note: Gentamicin sulfate Sulfate is a bactericidal agent that is not effective against viruses or fungi in skin infections. It is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria. Good results have been obtained in the treatment of infected stasis and other skin ulcers, infected superficial burns, paronychia, infected insect bites and stings, infected lacerations and abrasions, and wounds from minor surgery. Patients sensitive to neomycin can be treated with Gentamicin sulfate Sulfate, although regular observation of patients sensitive to topical antibiotics is advisable when such patients are treated with any topical antibiotic. Gentamicin sulfate Sulfate Cream USP, 0.1% is recommended for wet, oozing primary infections, and greasy, secondary infections, such as pustular acne or infected seborrheic dermatitis. Gentamicin sulfate sulfate ointment helps retain moisture and has been useful in infection on dry eczematous or psoriatic skin. If a water-washable preparation is desired, the cream is preferable. Gentamicin sulfate Sulfate Cream USP, 0.1% has been used successfully in infants over one year of age, as well as in adults and children.
How should I use Gentamicin sulfate?
Use Gentamicin sulfate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Gentamicin sulfate may be used around the eye or in the eye, as directed by your doctor. To use Gentamicin sulfate in the eye, first, wash your hands. Using your index finger, pull the lower eyelid away from your eye to form a pouch. Squeeze a thin strip of ointment into the pouch. After using Gentamicin sulfate, gently close your eyes for 1 to 2 minutes. Wash your hands to remove any medicine that may be on them. Wipe the applicator tip with a clean, dry tissue.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- Do not wear contact lenses while you are using Gentamicin sulfate. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
- Gentamicin sulfate is only for the eye. Do not get it in your nose or mouth.
- To clear up your infection completely, use Gentamicin sulfate for the full course of treatment. Keep using it even if you feel better in a few days.
- Using Gentamicin sulfate at the same times each day will help you to remember to use it.
- If you miss a dose of Gentamicin sulfate, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Gentamicin sulfate.
Uses of Gentamicin sulfate in details
This medication is used to treat minor skin infections (such as impetigo, folliculitis) or minor infections related to some skin conditions (such as eczema, psoriasis, minor burns/cuts/wounds). Gentamicin sulfate works by stopping the growth of certain bacteria. It belongs to a class of drugs known as aminoglycoside antibiotics.
This antibiotic only treats bacterial infections. It will not work for virus or fungus infections. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.
How to use Gentamicin sulfate topical
This medication is for use on the skin only.
Wash your hands before using. Clean and dry the affected area as directed. If you are treating impetigo, remove any dried, crusty skin to increase contact between the antibiotic and the infected area. Then gently apply a small amount of medication in a thin layer as directed by your doctor, usually 3 to 4 times a day. You may cover the area with a sterile gauze bandage if so directed. Keep the infected area clean. Wash your hands after use, unless you are using this product to treat the hands.
Avoid getting this medication in your eyes, nose, or mouth. If this occurs, wipe off the medication and rinse thoroughly with water.
Dosage and length of treatment is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.
Continue to use this medication for the full length of treatment prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.
Tell your doctor if your skin infection persists or if it worsens.
Gentamicin sulfate description
Gentamicin sulfate also contains the following ingredients: Methyl paraben 1.8 mg, propyl paraben 0.2 mg, sodium bisulfite 3.2 mg, disodium ethylenediaminetetraacetate 0.1 mg and water for injection.
Gentamicin sulfate sulfate injection is a sterile solution of Gentamicin sulfate sulfate water for injection. It contains the equivalent of not less than 90% and not more than 125% of the labeled amount of Gentamicin sulfate. It may contain suitable buffers, preservatives, sequestering agents, unless it is intended for intrathecal use, in which case it contains only suitable tonicity agents.
Gentamicin sulfate dosage
A small amount of Gentamicin sulfate Sulfate Cream USP, 0.1% should be applied gently to lesions three or four times a day. The area treated may be covered with a gauze dressing if desired. In impetigo contagiosa, the crusts should be removed before application of Gentamicin sulfate Sulfate Cream USP, 0.1% to permit maximum contact between the antibiotic and the infection. Care should be exercised to avoid further contamination of the infected skin. Infected stasis ulcers have responded well to Gentamicin sulfate Sulfate under gelatin packing.
Gentamicin sulfate interactions
See also:
What other drugs will affect Gentamicin sulfate?
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.
To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.
Some products that may interact with this drug include: aminoglycoside antibiotics given by injection (such as amikacin, Gentamicin sulfate, tobramycin).
This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.
Gentamicin sulfate side effects
See also:
What are the possible side effects of Gentamicin sulfate?
In patients with dermatoses treated with Gentamicin sulfate Sulfate, irritation (erythema and pruritus) that did not usually require discontinuance of treatment has been reported in a small percentage of cases. There was no evidence of irritation or sensitization, however, in any of these patients patch-tested subsequently with Gentamicin sulfate Sulfate on normal skin. Possible photosensitization has been reported in several patients but could not be elicited in these patients by reapplication of Gentamicin sulfate Sulfate followed by exposure to ultraviolet radiation.
Gentamicin sulfate contraindications
See also:
What is the most important information I should know about Gentamicin sulfate?
Gentamicin sulfate Sulfate Sterile Ophthalmic Solution is contraindicated in patients with known hypersensitivity to any of the components.
What is Miconazole nitrate?
Miconazole nitrate topical is an antifungal medication. Miconazole nitrate topical prevents fungus from growing on your skin.
Miconazole nitrate topical is used to treat skin infections such as athlete's foot, jock itch, ringworm, tinea versicolor (a fungus that discolors the skin), and yeast infections.
Miconazole nitrate topical may also be used for purposes other than those listed in this medication guide.
Miconazole nitrate indications
Adwizole (Miconazole nitrate nitrate) Spray is indicated for the treatment of fungal infections in dogs and cats caused by Microsporum canis, Microsporum gypseum and Trichophyton mentagrophytes.
How should I use Miconazole nitrate?
Use Miconazole nitrate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Miconazole nitrate comes with an additional patient leaflet. Read it carefully and reread it each time you get Miconazole nitrate refilled.
- Miconazole nitrate is for vaginal use only. Do not use in the eyes or take by mouth.
- Using the applicator provided, insert 1 suppository high into the vagina at bedtime for 7 days.
- Miconazole nitrate comes with one applicator to be used for all 7 days of treatment. Do not throw away applicator after use. Separate the pieces of the applicator and wash with warm, soapy water immediately after use. Rinse thoroughly. Make sure the applicator is completely dry before the next use.
- Wash your hands immediately after using Miconazole nitrate.
- To clear up your infection completely, continue using Miconazole nitrate for the full course of treatment.
- If you miss a dose of Miconazole nitrate, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Miconazole nitrate.
Uses of Miconazole nitrate in details
Miconazole nitrate is an imidazole (organic compound) antifungal agent used to treat fungal and associated bacterial super infections of the skin and nails Miconazole nitrate is also used for oral treatment and prevention of fungal infections of the mouth, throat and food pipe Miconazole nitrate is effectively used in vulvovaginal (vagina and external genital organs) candidiasis (thrush) and other yeast infection of the vagina. Further, Miconazole nitrate is also prescribed for napkin rash and inflammation of the folds of tissue surrounding the nails of toes or fingers (paronychia).
Miconazole nitrate description
Miconazole nitrate: Each mL of solution contains Miconazole nitrate nitrate, in a soothing, cooling solution, which helps to keep the infection site dry.
Miconazole nitrate Tinea: Each gram of cream contains Miconazole nitrate nitrate, dimethicone and phenethyl alcohol in a lanolin-free aqueous soft cream base. It has a pH of 5.
Each gram of powder contains Miconazole nitrate nitrate in a zinc oxide menthol and talc powder base.
All cream products are lanolin-free, propylene glycol-free, colour-free, perfume-free and paraben-free to avoid irritant reactions.
Miconazole nitrate dosage
Miconazole nitrate Dosage
Generic name: Miconazole nitrate nitrate
Dosage form: Cream
See also:
- Monistat 3 vaginal cream, vaginal suppositories
- Monistat 3 Combination Pack Triple Action cream
- Monistat 7 Combination Pack cream
- Monistat 7 Cream vaginal cream
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Sufficient Miconazole nitrate Cream should be applied to cover affected areas twice daily (morning and evening) in patients with tinea pedis, tinea cruris, tinea corporis, and cutaneous candidiasis, and once daily in patients with tinea versicolor. If Miconazole nitrate Cream is used in intertriginous areas, it should be applied sparingly and smoothed in well to avoid maceration effects.
Early relief of symptoms (2 to 3 days) is experienced by the majority of patients and clinical improvement may be seen fairly soon after treatment is begun; however, Candida infections and tinea cruris and corporis should be treated for two weeks and tinea pedis for one month in order to reduce the possibility of recurrence. If a patient shows no clinical improvement after a month of treatment, the diagnosis should be redetermined. Patients with tinea versicolor usually exhibit clinical and mycological clearing after two weeks of treatment.
More about Miconazole nitrate (Miconazole nitrate topical)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
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Consumer resources
- Miconazole nitrate cream
- Monistat Derm
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Professional resources
- Miconazole nitrate (FDA)
- Miconazole nitrate Nitrate (AHFS Monograph)
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- Monistat 3-Day Combination Pack
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Related treatment guides
- Cutaneous Candidiasis
- Tinea Corporis
- Tinea Cruris
- Tinea Pedis
- Tinea Versicolor
Miconazole nitrate interactions
See also:
What other drugs will affect Miconazole nitrate?
Oral anticoagulants, sulfonylurea hypoglycemics, phenytoin, carbamazepine, astemizole, cisapride & terfenadine.
Miconazole nitrate side effects
See also:
What are the possible side effects of Miconazole nitrate?
Applies to Miconazole nitrate topical: topical cream, topical gel/jelly, topical kit, topical lotion, topical ointment, topical powder, topical spray, topical tablet effervescent, topical tincture
In addition to its needed effects, some unwanted effects may be caused by Miconazole nitrate topical (the active ingredient contained in Miconazole nitrate). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Miconazole nitrate topical, check with your doctor or nurse as soon as possible:
- Blistering, burning, redness, skin rash, or other sign of skin irritation not present before use of this medicine
Miconazole nitrate contraindications
See also:
What is the most important information I should know about Miconazole nitrate?
When used by a person taking the anticoagulant medication warfarin, Miconazole nitrate may cause an adverse reaction which can lead to excessive bleeding or bruising.
Active ingredient matches for Betamethasone dipropionate/gentamicin sulfate/miconazole nitrate:
Betamethasone dipropionate/gentamicin sulfate/miconazole nitrate
References
- DailyMed. "MICONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "GENTAMICIN SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
