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Betamethasone Valerate Dosage |
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Betamethasone Valerate Cream/Betamethasone Valerate RD Cream: A small quantity should be applied to the affected area 2 or 3 times daily until improvement occurs. It may then be possible to maintain improvement by applying once a day or even less often or by using the appropriate ready-diluted (1 in 4) preparation Betamethasone Valerate RD Cream.
Betamethasone Valerate Cream: Betamethasone Valerate creams are especially appropriate for moist or weeping surfaces.
In the more resistant lesions eg, the thickened plaques of psoriasis on elbows and knees, the effect of Betamethasone Valerate can be enhanced, if necessary, by occluding the treatment area with polythene film. Overnight occlusion only is usually adequate to bring about a satisfactory response in such lesions thereafter, improvement can usually be maintained by regular application without occlusion.
Betamethasone Valerate RD Cream: A small amount of Betamethasone Valerate RD Cream may be applied up to 3 times daily. Betamethasone Valerate RD Cream is especially appropriate for moist or weeping surfaces.
Betamethasone Valerate Scalp Application: A small quantity of Betamethasone Valerate Scalp Application should be applied to the scalp night and morning until improvement is noticeable. It may then be possible to sustain improvement by applying once a day or less frequently.
Due to the flammable nature of Betamethasone Valerate Scalp Application, patients should avoid smoking, heat including the use of hair dryer or being near an open flame during application and immediately after use.
Children: Betamethasone Valerate is contraindicated in children <1 year.
Children are more likely to develop local and systemic side effects of topical corticosteroids and in general, require shorter courses and less potent agents than adults.
Care should be taken when using Betamethasone Valerate to ensure the amount applied is the minimum that provides therapeutic benefit.
Elderly: The greater frequency of decreased hepatic or renal function in the elderly may delay elimination if systemic absorption occurs. Therefore, the minimum quantity should be used for the shortest duration to achieve the desired clinical benefit.
Renal/Hepatic Impairment: In case of systemic absorption (when application is over a large surface area for a prolonged period), metabolism and elimination may be delayed therefore increasing the risk of systemic toxicity. Therefore, the minimum quantity should be used for the shortest duration to achieve the desired clinical benefit.
Many drugs can affect Betamethasone Valerate. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Betamethasone Valerate drug interactions (in more detail)
Concurrent use of barbiturates, carbamazepine, phenytoin, primidone or rifampicin may enhance the metabolism and reduce the effects of systemic corticosteroids. Conversely, oral contraceptives or ritonavir may increase plasma concentrations of corticosteroids.
Use of corticosteroids with potassium-depleting diuretics eg, thiazides or furosemide may cause excessive potassium loss. There is also an increased risk of hypokalemia with concurrent amphotericin B or bronchodilator therapy with xanthines or β2 agonist.
There may be an increased incidence of gastrointestinal bleeding and ulceration when corticosteroids are given with NSAIDs. Corticosteroids may alter response to anticoagulants increasing requirements of antidiabetic drugs and antihypertensives.
Corticosteroids may decrease serum concentrations of salicylates and may decrease the effect of antimuscarinics in myasthenia gravis.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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