Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately.
Proper storage of Betamethasone solution:
Store Betamethasone solution at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Betamethasone solution out of the reach of children and away from pets.
Overdose of Betamethasone in details
When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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Symptoms: Excessive or prolonged use of topical corticosteroids can suppress pituitary-adrenal function, resulting in secondary adrenal insufficiency and produce manifestations of hypercorticism, including Cushing's disease.
A single overdose of gentamicin would not be expected to produce symptoms. Excessive or prolonged use of topical antibiotics may lead to overgrowth of lesions by non-susceptible organisms.
Systemically, tolnaftate is pharmacologically inactive.
Clioquinol rarely produces iodism.
Treatment: Appropriate symptomatic treatment is indicated. Acute hypercorticoid symptoms are usually reversible. Treat electrolyte imbalance, if necessary. In case of chronic toxicity, slow withdrawal of corticosteroids is advised.
If overgrowth by non-susceptible organisms occurs, stop treatment with Betamethasone, Gentamicin, Tolnaftate, Clioquinol (Betamethasone) Cream and institute appropriate therapy.
What should I avoid while taking Betamethasone?
Avoid getting this medicine in your eyes. If contact does occur, rinse with water. Do not use Betamethasone topical on broken or infected skin. Also avoid using this medicine in open wounds.
Avoid applying Betamethasone topical to the skin of your face, underarms, or groin area without your doctor's instruction.
Do not use Betamethasone topical to treat any condition that has not been checked by your doctor.
Betamethasone warnings
Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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Some medical conditions may interact with Betamethasone Valerate Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have thinning of the skin, a skin infection, tuberculosis (TB), chickenpox, shingles, measles, or a positive TB skin test, or have recently been vaccinated
Some MEDICINES MAY INTERACT with Betamethasone Valerate Cream. Because little, if any, of Betamethasone Valerate Cream is absorbed into the blood, the risk of it interacting with another medicine is low.
Ask your health care provider if Betamethasone Valerate Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Avoid long-term use, especially near the eyes, on the face, on the genital and rectal areas, and in skin folds.
Betamethasone Valerate Cream is for external use only. Avoid contact with eyes or eyelids. If you get Betamethasone Valerate Cream in your eyes, immediately flush with cool tap water.
Do not use Betamethasone Valerate Cream for other skin conditions at a later time.
If Betamethasone Valerate Cream was prescribed to treat the diaper area of a child, avoid using tight-fitting diapers or plastic pants.
Betamethasone Valerate Cream should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Betamethasone Valerate Cream while you are pregnant. It is not known if Betamethasone Valerate Cream is found in breast milk. If you are or will be breast-feeding while you use Betamethasone Valerate Cream, check with your doctor. Discuss any possible risks to your baby.
What should I discuss with my healthcare provider before taking Betamethasone?
For all uses of ReadySharp Betamethasone (Betamethasone (systemic)):
If you have an allergy to Betamethasone or any other part of ReadySharp Betamethasone (Betamethasone (systemic)).
If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
If you have a herpes infection of the eye.
If you have any of these health problems: A fungal infection or malaria infection in the brain.
Injection (if given in the muscle):
If you have idiopathic thrombocytopenic purpura (ITP).
This is not a list of all drugs or health problems that interact with ReadySharp Betamethasone (Betamethasone (systemic)).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take ReadySharp Betamethasone (Betamethasone (systemic)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Betamethasone precautions
Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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If irritation or sensitization develops with the use of Betamethasone, Gentamicin, Tolnaftate, Clioquinol (Betamethasone) Cream, treatment should be discontinued and appropriate therapy instituted.
Any of the side effects that are reported following systemic use of corticosteroids, including adrenal suppression may also occur with topical corticosteroids, especially in infants and children.
Systemic absorption of Betamethasone, Gentamicin, Tolnaftate, Clioquinol (Betamethasone) Cream will be increased if extensive body surface areas are treated or if the occlusive technique is used. Suitable precautions should be taken under these conditions or when long-term use is anticipated, particularly in infants and children.
Cross-allergenicity among aminoglycosides has been demonstrated.
Systemic absorption of topically applied gentamicin may be increased if extensive body surface areas are treated, especially over prolonged time periods or in the presence of dermal disruption. In these cases, the undesirable effects which occur following systemic use of gentamicin may potentially occur. Cautious use is recommended under these conditions, particularly in infants and children.
Prolonged use of topical antibiotics occasionally may result in overgrowth of non-susceptible organisms. If this occurs or if irritation, sensitization or superinfection develops, treatment with Betamethasone, Gentamicin, Tolnaftate, Clioquinol (Betamethasone) Cream should be discontinued and appropriate therapy instituted. Slight staining of linens or clothing due to clioquinol may occur.
Betamethasone, Gentamicin, Tolnaftate, Clioquinol (Betamethasone) Cream is not for ophthalmic use.
Use in Children: Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced hypothalamic-pituitaryadrenal (HPA) axis suppression and to exogenous corticosteroids effects than mature patients because of greater absorption due to large skin surface area to body weight ratio.
HPA axis suppression, Cushing's syndrome, linear growth retardation, delayed weight gain, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include low plasmacortisol levels and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include a bulging fontanelle, headaches and bilateral papilledema.
What happens if I miss a dose of Betamethasone?
When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.
Call your doctor for instructions if you miss an appointment for your Betamethasone injection.
References
DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
