Consists of Estradiol, Prasterone
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Binodian Depot Pregnancy |
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Consists of Estradiol, Prasterone
Estrogenic agents have been associated with urogenital abnormalities in offspring that manifest later in life. Vaginal adenosis, squamous cell dysplasia of the uterine cervix and vaginal cancer have developed later in life in female offspring. In male offspring, the risks of urogenital abnormalities and testicular cancer later in life are increased.
Estradiol (Binodian Depot) has been assigned to pregnancy category X by the FDA. There are no controlled data in human pregnancy. Estradiol (Binodian Depot) is contraindicated during pregnancy.
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Limited data are available on the excretion of Estradiol (Binodian Depot) into human milk. The American Academy of Pediatrics considers Estradiol (Binodian Depot) to be usually compatible with breast-feeding despite reports of "withdrawal" and "vaginal bleeding". Estradiol (Binodian Depot) has been shown to decrease to quantity and quality of the milk. Estrogens are not indicated for the prevention of postpartum breast engorgement. The manufacturer recommends that caution be used when administering Estradiol (Binodian Depot) to nursing women.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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