Biocobal GB Uses

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What is Biocobal GB?

Biocobal GB is a form of vitamin B12. Vitamin B12 is important for the brain and nerves, and for the production of red blood cells.

Biocobal GB is used to treat vitamin B12 deficiency. Biocobal GB is sometimes used in people with pernicious anemia, diabetes, and other conditions.

Biocobal GB may also be used for purposes not listed in this medication guide.

Biocobal GB indications

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Tab: Treatment of peripheral neuropathies. Inj: Megaloblastic anemia due to vit B12 deficiency, peripheral neuropathies.

Uses of Biocobal GB in details

Biocobal GB is an active form of vitamin B12, which is used to treat anemia as well as nerve damage with numbness, tingling, pain in various neurological disorders.

Biocobal GB description

Each ampoule also contains D-mannitol 50 mg as an additive. pH 5.3-7.3. Osmotic Pressure (to physiological saline): Approximately 1.

Mecobalamin is α-(5,6-dimethylbenzimidazolyl)-Co-methyl-cobamide.

Molecular Formula: C63H91CoN13O14P.

Molecular Weight: 1344.4.

Mecobalamin occurs as a dark red, odorless and almost tasteless crystal or crystalline powder. It is sparingly soluble in water, methanol and ethanol and practically insoluble in acetone, ether and chloroform. Mecobalamin is hygroscopic and decomposes upon exposure to light.

Biocobal GB dosage

Tablet: Adults: Usual Daily Dose: 3 tabs, equivalent to a total of 1500 mcg of mecobalamin, administered orally in 3 divided doses. The dose should be adjusted according to age of patient and severity of symptoms.

Injection: Peripheral Neuropathies: The usual adult dosage is 1 amp, equivalent to 500 mcg of mecobalamin administered IM or IV 3 times a week. The dosage should be adjusted according to age of patient and severity of symptoms.

Megaloblastic Anemia: The usual adult dosage is 1 amp, equivalent to 500 mcg of mecobalamin administered IM or IV 3 times a week. After approximately 2 months of medication, the dose should be reduced to a single administration of 1 amp at 1- to 3-month intervals for maintenance therapy.

What other drugs will affect Biocobal GB?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect Biocobal GB, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Drug Interactions (in more detail)

Biocobal GB side effects

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What are the possible side effects of Biocobal GB?

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Tablet: Gastrointestinal: Symptoms eg, anorexia, nausea or diarrhea may occur infrequently.

Dermatological: Skin rash may occur rarely.

Others: Prolonged use of larger doses of Biocobal GB is not recommended for patients whose occupation requires handling of mercury or its compounds.

Injection: Hypersensitivity: Use of Biocobal GB should be discontinued if symptoms of hypersensitivity eg, eruptions, occur.

Others: Pain and induration may infrequently occur at the site of IM injection and headache, sweating or hot sensation may rarely occur.

What is the most important information I should know about Biocobal GB?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Active ingredient matches for Biocobal GB:

Methylcobalamin


Unit description / dosage (Manufacturer)Price, USD
Biocobal GB 500 mcg+300 mg Tablet$ 0.13

List of Biocobal GB substitutes (brand and generic names):

Betanuron OD 1500mcg Injection (Speciality Meditech Pvt Ltd)$ 0.24
BLIEU CAPSULE 1 strip / 10 capsules each (Ozone Pharmaceuticals Ltd)$ 1.26
Bone C Plus Capsule (Molekule (India) Pvt. Ltd.)$ 0.15
Braingates 5 & 10 Injection (Health Guard (India) Pvt. Ltd.)$ 0.55
BUNALCO INJECTION 1 vial / 1 injection each (Jarun Pharmaceuticals)$ 0.66
C Cobal 1500 mcg Capsule (Carion Healthcare Pvt. Ltd.)$ 0.14
C Cobal Plus Capsule (Carion Healthcare Pvt. Ltd.)$ 0.14
Capin G 300 mg+500 mcg Capsule (Kamakshi Drugs & Pharmaceuticals)$ 0.15
Carecobal 500 mcg Tablet (Vivid Biotek Pvt. Ltd.)$ 0.05
Carecobal-G 500 mcg+300 mg Capsule (Vivid Biotek Pvt. Ltd.)$ 0.20
Carrac 1500+1500 Capsule (D.R. Johns Labs)$ 0.19
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Centric M 1500 mcg Injection (Vatican Life Sciences Pvt Ltd)$ 0.39
COB Z 0.5MG INJECTION 1 vial / 2 ML injection each (Medinova Labs)$ 0.36
COBA FORTE 500 MCG INJECTION 1 vial / 1 injection each (Emcure Pharmaceuticals Ltd)$ 0.40
Cobadin Methylcobalamin 1000 mcg, thiamine hydrochloride 100 mg, pyridoxine hydrochloride 50mg, D-panthenol 50 mg. INJ / 2ml (Phoenix)$ 0.66
COBADIN inj 2ml (Phoenix)$ 0.66
COBALAN PLUS 1500 MCG INJECTION 1 vial / 2 ML injection each (Stadchem Of India)$ 0.55
Cobalvit GT 300 mg+500 mcg Tablet (Intra Labs India Pvt Ltd)$ 0.14
COBANURON INJECTION 1 vial / 1 ML injection each (Life Sciences Inc)$ 0.17
Cobarax 1500 mcg Injection (Rax Health Care Pvt. Ltd.)$ 0.10
Cobatp 500 mcg Tablet (Taurus Laboratories Pvt. Ltd.)$ 0.07
Cobimep G 300 mg+500 mcg Capsule (Mepfarma (Alna Biotech))$ 0.13
Cobimep P 500 mcg+75 mg Capsule (Mepfarma (Alna Biotech))$ 0.15
Cobina 1500 mcg Injection (Symbiosis Labs (P) Ltd.)$ 0.18
Cobina 500 mcg Injection (Symbiosis Labs (P) Ltd.)$ 0.28
Colaba B Inj Injection (Dallas Formulations Pvt Ltd)$ 0.59
Comago 300 mg+500 mcg Tablet (Bajaj Pharmaceuticals)$ 0.11
Cormin 500 mcg Injection (Coral Pharmaceuticals)$ 0.36
COSTRUM INJECTION 1 vial / 2 ML injection each (Canvarzys Pharmaceuticals)$ 0.27
CYCOBAL INJECTION 1 vial / 1 ML injection each (Alembic Pharmaceuticals Ltd)$ 0.07
Cymate 1000 mcg Injection (Cytochem Health Care (India) Pvt. Ltd.)$ 0.19
CYNOCAL M 500 MCG/1000 MCG INJECTION 1 vial / 2 injections each (Ozone Pharmaceuticals Ltd)$ 0.24
CYNOCAL M FORTE INJECTION 1 vial / 2 ML injection each (Ozone Pharmaceuticals Ltd)$ 1.21
CYNOCAL-M FORTE soft-gelatin cap 10's (Ozone Pharma)$ 1.13
DAVICOB tab 1500 mcg x 10's (DML)$ 0.71
Divinerv GB 300 mg+500 mcg Tablet (Quest Pharmaceuticals)$ 0.11
Ducat 1000 mcg Injection (Kamakshi Drugs & Pharmaceuticals)$ 0.10
Dulane M 30 mg+1500 mcg Capsule (Sun Pharmaceutical Industries Ltd.)$ 0.11
Dulane M 20 mg+1500 mcg Capsule (Sun Pharmaceutical Industries Ltd.)$ 0.08
DULANE M 20MG/1.5MG TABLET 1 strip / 10 tablets each (Sun Pharmaceutical Industries Ltd.)$ 1.12
DULANE M 30MG/1500MCG TABLET 1 strip / 10 tablets each (Sun Pharmaceutical Industries Ltd.)$ 1.23
Dulane M 20mg/1.5mg Tablet (Sun Pharmaceutical Industries Ltd.)$ 0.11

References

  1. PubChem. "methylcobalamin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "methylcobalamin". http://www.drugbank.ca/drugs/DB03614 (accessed September 17, 2018).
  3. MeSH. "MeSH Tree: MeSH (Medical Subject Headings) is the NLM controlled vocabulary thesaurus used for indexing articles for PubMed.". http://www.nlm.nih.gov/mesh/meshhome... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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