Bisincof Overdose

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Bisincof warnings

Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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Patients with severe hepatic impairment should be given a lower dose initially, as these patients may have a slower clearance of Loratadine (Bisincof), the recommended starting dose is 5 mg once daily or 10 mg on alternate days.

Must be used with caution in patients with gastric ulcer.

RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION

Has not been established whether the administration of Loratadine (Bisincof), Ambroxol (Bisincof) can represent any change during pregnancy. Therefore, the drug should be used only if the potential benefit to the mother justifies the potential risk to the fetus.

It has been established that Loratadine (Bisincof) is excreted in human milk, because of the risk potential of antihistamines for infants, particularly newborns and premature babies should decide about stopping breast-feeding or discontinuation of the drug.

References

  1. DailyMed. "LORATADINE; PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
  3. DrugBank. "loratadine". http://www.drugbank.ca/drugs/DB00455 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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