Cafunten forte Dosage

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Consists of Betamethasone dipropionate, clotrimazole, neomycin sulfate

Dosage of Betamethasone dipropionate (Cafunten forte) in details

infoThe dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Apply a thin film of Betamethasone dipropionate (Cafunten forte), 0.5% (augmented) to the affected skin areas once or twice daily. Therapy should be discontinued when control is achieved. Betamethasone dipropionate (Cafunten forte), 0.5% (augmented)is a high-potency corticosteroid. Treatment with Betamethasone dipropionate (Cafunten forte), 0.5% (augmented)should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.

Betamethasone dipropionate (Cafunten forte), 0.5% (augmented)should not be used with occlusive dressings unless directed by a physician.

Betamethasone dipropionate (Cafunten forte), 0.5% (augmented)is for topical use only. It is not for oral, ophthalmic, or intravaginal use.

Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.

What other drugs will affect Betamethasone dipropionate (Cafunten forte)?

Many drugs can affect Betamethasone dipropionate (Cafunten forte). This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Betamethasone dipropionate (Cafunten forte) drug interactions (in more detail)

Betamethasone dipropionate (Cafunten forte) interactions

infoInteractions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Betamethasone dipropionate (Cafunten forte), it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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There are no known drug interactions with topical Betamethasone dipropionate (Cafunten forte).

Dosage of Clotrimazole (Cafunten forte) in details

infoThe dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.

Usual Adult Dose for Tinea Corporis

Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Tinea Cruris

Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Tinea Pedis

Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Cutaneous Candidiasis

Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Tinea Versicolor

Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Vaginal Candidiasis

Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% Clotrimazole (Cafunten forte) to affected area two times daily for 7 consecutive days.

Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% Clotrimazole (Cafunten forte) to affected area two times daily for 7 consecutive days.

Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.

Regimen 4: One applicatorful of 1% Clotrimazole (Cafunten forte) vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.

Regimen 5: One applicatorful of 2% Clotrimazole (Cafunten forte) vaginal cream intravaginally once daily (preferably at bedtime) for 3 consecutive days.

Studies have shown the three and seven day courses of Clotrimazole (Cafunten forte) to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of Clotrimazole (Cafunten forte).

Weekly or monthly Clotrimazole (Cafunten forte) vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.

Usual Pediatric Dose for Tinea Corporis

> 3 years: Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Tinea Cruris

> 3 years: Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Tinea Pedis

> 3 years: Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Cutaneous Candidiasis

> 3 years: Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Tinea Versicolor

> 3 years: Apply Clotrimazole (Cafunten forte) topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Vaginal Candidiasis

> 12 years: Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% Clotrimazole (Cafunten forte) to affected area two times daily for 7 consecutive days.

Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% Clotrimazole (Cafunten forte) to affected area two times daily for 7 consecutive days.

Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.

Regimen 4: One applicatorful of 1% Clotrimazole (Cafunten forte) vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.

Studies have shown the three and seven day courses of Clotrimazole (Cafunten forte) to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of Clotrimazole (Cafunten forte).

Weekly or monthly Clotrimazole (Cafunten forte) vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

What other drugs will affect Clotrimazole (Cafunten forte)?

Avoid using other vaginal creams or douches at the same time as Clotrimazole (Cafunten forte) unless your doctor approves.

Drugs other than those listed here may also interact with Clotrimazole (Cafunten forte) vaginal. Talk to your doctor and pharmacist before taking any prescription or over the counter medicines.

Clotrimazole (Cafunten forte) interactions

infoInteractions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Clotrimazole (Cafunten forte), it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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Clotrimazole (Cafunten forte) should be used cautiously in patients with hyperthyroidism, hypertension and cardiac arrhythmias. All vasopressors should be used cautiously in patients taking monoamine oxidase (MAO) inhibitors.

Clotrimazole (Cafunten forte) should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity.

Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other such drug has subsided.

Administration of epinephrine to patients receiving cyclopropane or halogenated hydrocarbon general anesthetics such as halothane which sensitize the myocardium, may induce cardiac arrhythmia.. When encountered, such arrhythmias may respond to administration of a beta-adrenergic blocking drug. Clotrimazole (Cafunten forte) also should be used cautiously with other drugs (e.g., digitalis, glycosides) that sensitize the myocardium to the actions of sympathomimetic drugs.

Diuretic agents may decrease vascular response to pressor drugs such as epinephrine.

Clotrimazole (Cafunten forte) may antagonize the neuron blockade produced by guanethidine resulting in decreased antihypertensive effect and requiring increased dosage of the latter.

Dosage of Neomycin sulfate (Cafunten forte) in details

infoThe dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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To minimize the risk of toxicity, use the lowest possible dose and the shortest possible treatment period to control the condition. Treatment for periods longer than two weeks is not recommended.

Hepatic Coma

For use as an adjunct in the management of hepatic coma, the recommended dose is 4-12 grams per day given in the following regimen:

1. Withdraw protein from diet. Avoid use of diuretic agents.

2. Give supportive therapy, including blood products, as indicated.

3. Give Neomycin sulfate (Cafunten forte) Tablets in doses of 4-12 grams of Neomycin sulfate (Cafunten forte) per day (eight to 24 tablets) in divided doses. Treatment should be continued over a period of five to six days, during which time protein should be returned incrementally to the diet.

4. If less potentially toxic drugs cannot be used for chronic hepatic insufficiency, neomycin in doses of up to four grams daily (eight tablets per day) may be necessary. The risk for the development of neomycin-induced toxicity progressively increases when treatment must be extended to preserve the life of a patient with hepatic encephalopathy who has failed to fully respond. Frequent periodic monitoring of these patients to ascertain the presence of drug toxicity is mandatory. Also, neomycin serum concentrations should be monitored to avoid potentially toxic levels. The benefits to the patient should be weighed against the risks of nephrotoxicity, permanent ototoxicity and neuromuscular blockade following the accumulation of neomycin in the tissues.

Preoperative Prophylaxis for Elective Colorectal Surgery

Listed below is an example of a recommended bowel preparation regimen. A proposed surgery time of 8:00 am. has been used.

Pre-op Day 3: Minimum residue or clear liquid diet. Bisacodyl, 1 tablet orally at 6:00 p. m.

Pre-op Day 2: Minimum residue or clear liquid diet. Magnesium sulfate, 30 mL, 50% solution (15 g) orally at 10:00 a.m., 2:00 p.m., and 6:00 p.m. Enema at 7:00 p.m. and 8:00 p.m.

Pre-op Day 1: Clear liquid diet. Supplemental (IV) fluids as needed. Magnesium sulfate, 30 mL, 50% solution (15 g) orally at 10:00 a. m., and 2:00 p.m. Neomycin sulfate (Cafunten forte) (1 g) and erythromycin base (1 g) orally at 1:00 p. m., 2:00 p.m. and 11:00 p.m. No enema.

Day of Operation: Patient evacuates rectum at 6:30 a.m. for scheduled operation at 8:00 a.m.

How supplied

Neomycin sulfate (Cafunten forte) Tablets, USP, 500 mg (equivalent to 350 mg of neomycin base per tablet) are available as round, off-white, unscored tablets, imprinted "BL" and "18", in bottles of 100 tablets.

Store at controlled room temperature 15°-30° C( 59°-86° F). Dispense in tight containers as defined in the USP/NF.

CAUTION: Federal law prohibits dispensing without prescription.

What other drugs will affect Neomycin sulfate (Cafunten forte)?

Neomycin can harm your kidneys, and this effect is increased when you also use certain other medicines harmful to the kidneys. Before using neomycin, tell your doctor about all other medicines you use. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.

Before you take neomycin, tell your doctor if you are using any other antibiotics, such as

  • amikacin (Amikin)
  • amphotericin-B (Amphotec);
  • bacitracin (Baci IM);
  • colistimethate (Coly Mycin M);
  • gentamicin (Garamycin);
  • kanamycin (Kantrex);
  • paromomycin (Humatin, Paromycin);
  • polymyxin B sulfate;
  • penicillin V (PC Pen VK);
  • streptomycin;
  • tobramycin (Nebcin, Tobi); or
  • vancomycin (Vancocin, Vancoled).

Tell your doctor about all other medicines you use, especially:

  • cisplatin (Platinol);
  • digoxin (digitalis, Lanoxin, Lanoxicaps);
  • methotrexate (Rheumatrex, Trexall);
  • vitamin B-12;
  • antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or tenofovir (Viread);
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • a botulism toxin medication (Botox, Dysport, Myobloc, Xeomin, and others); or
  • a diuretic (water pill) such as bumetanide (Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), or torsemide (Demadex).

This list is not complete and other drugs may interact with neomycin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Neomycin sulfate (Cafunten forte) interactions

infoInteractions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Neomycin sulfate (Cafunten forte), it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.

Caution should be taken in concurrent or serial use of other neurotoxic and/ or nephrotoxic drugs because of possible enhancement of the nephrotoxicity and/or ototoxicity of neomycin.

Caution should also be taken in concurrent or serial use of other aminoglycosides and polymyxins because they may enhance neomycin's nephrotoxicity and/or ototoxicity and potentiate Neomycin sulfate (Cafunten forte)'s neuromuscular blocking effects.

Oral neomycin inhibits the gastrointestinal absorption of penicillin V, oral vitamin B-12, methotrexate and 5-fluorouracil. The gastrointestinal absorption of digoxin also appears to be inhibited. Therefore, digoxin serum levels should be monitored.

Oral Neomycin sulfate (Cafunten forte) may enhance the effect of coumarin in anticoagulants by decreasing vitamin K availability.

References

  1. DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "BETAMETHASONE DIPROPIONATE; CLOTRIMAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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