Calcium carbonate Actions
Calcium carbonate is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. It also inhibits the action of pepsin by increasing the pH and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (HCO3-) and prostaglandins. Neutralization of hydrochloric acid results in the formation of calcium chloride, carbon dioxide and water. Approximately 90% of calcium chloride is converted to insoluble calcium salts (e.g. Calcium carbonate and calcium phosphate).
Take Calcium carbonate exactly as directed by your doctor or follow the directions on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Swallow the Calcium carbonate tablets and capsules with a full glass of water.
Chew the chewable forms of Calcium carbonate completely before swallowing.
Use the Calcium carbonate powder as directed. Allow the powder to dissolve completely, then consume the mixture.
Shake the Calcium carbonate suspension well before measuring a dose. To ensure that you get the correct dose, use a dose-measuring spoon or cup, not a regular table spoon to measure the liquid. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
Take calcium with meals to increase its absorption by the body, unless otherwise directed by your doctor.
Store Calcium carbonate at room temperature away from moisture and heat.
Capsules may be swallowed whole or opened and the contents mixed with food or drink.
Gastric-peptic disease occurs as a result of an imbalance between protective factors, such as mucus, bicarbonate, and prostaglandin secretion, and aggressive factors, such as hydrochloric acid, pepsin, and Helicobacter pylori (H. pylori). Antacids work by restoring acid-base balance, attenuating the pepsin activity and increasing bicarbonate and prostaglandin secretion. The acid-neutralizing capacity of Calcium carbonate is 58 mEq/15 ml. When used as a nutritional supplement, Calcium carbonate acts by directly increasing calcium stores within the body.
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Information checked by Dr. Sachin Kumar, MD Pharmacology