Antacids are taken by mouth to relieve heartburn, sour stomach, or acid indigestion. They work by neutralizing excess stomach acid. Some Calcium carbonate combinations also contain simethicone, which may relieve the symptoms of excess gas. Antacids alone or in combination with simethicone may also be used to treat the symptoms of stomach or duodenal ulcers.
With larger doses than those used for the Calcium carbonate effect, magnesium hydroxide (magnesia) and magnesium oxide antacids produce a laxative effect. The information that follows applies only to their use as an Calcium carbonate.
Some antacids, like aluminum carbonate and aluminum hydroxide, may be prescribed with a low-phosphate diet to treat hyperphosphatemia (too much phosphate in the blood). Aluminum carbonate and aluminum hydroxide may also be used with a low-phosphate diet to prevent the formation of some kinds of kidney stones. Aluminum hydroxide may also be used for other conditions as determined by your doctor.
These medicines are available without a prescription. However, your doctor may have special instructions on the proper use and dose of these medicines for your medical problem.
Calcium carbonate indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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this Calcium carbonate is useful for the temporary relief of occasional indigestion and heartburn. Frequent, daily or nightly symptoms usually mean a more serious problem. Antacids by themselves do not correct these problems. The medications that are now available to treat acid problems are generally superior to antacids.
The second and more important use of calcium carbonate is as a source of calcium, necessary for bones and teeth and to prevent osteoporosis. A quart of milk contains about 1500 mg of calcium which is about what you need. Otherwise this or a similar calcium preparation can be taken.
How should I use Calcium carbonate?
Use calcium carbonate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take calcium carbonate by mouth with or without food.
Take calcium carbonate with a full glass of water (8 oz/240 mL).
Do not take an Calcium carbonate that has aluminum in it within 1 hour before or 2 hours after you take calcium carbonate.
If you take azole antifungals (eg, ketoconazole), bisphosphonates (eg, etidronate), cation exchange resins (eg, sodium polystyrene sulfonate), cephalosporins (eg, cefdinir), direct thrombin inhibitors (eg, dabigatran), iron, mycophenolate, quinolones (eg, ciprofloxacin), tetracyclines (eg, minocycline), or thyroid hormones (eg, levothyroxine), ask your doctor how to take it with calcium carbonate.
If you miss a dose of calcium carbonate, take it as soon as you remember. Continue to take it as directed by your doctor or on the package label.
Ask your health care provider any questions you may have about how to use calcium carbonate.
Uses of Calcium carbonate in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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This medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).
Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Having the right amount of calcium is important for building and keeping strong bones.
How to use Calcium carbonate
Take this medication by mouth with food. If your product contains calcium citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you are uncertain about any of the information, consult your doctor or pharmacist.
If you are using the chewable product, chew it well before swallowing.
If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Do not chew or swallow the tablet whole.
If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. Do not use a household spoon. If the liquid product is a suspension, shake the bottle well before each dose.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.
If you think you may have a serious medical problem, seek immediate medical attention.
Calcium carbonate description
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Each Calcium carbonate milk powd contains: Energy Density 1 kCal/mL. Energy Distribution: Protein: Fat: CHO 13:37:50, Protein 32.5 g/L, CHO 125.7 g/L, Fat 42 g/L, Na 500 mg/L, K 1,250 mg/L, Mg 200 mg/L, P 500 mg/L, osmolality 300 mOsmol/kg H2O.
Each Calcium carbonate oral liqd (ready-to-drink) contains: Energy Density 1 kCal/mL. Energy Distribution: Protein: Fat: CHO 14:32:54, Protein 35 g/L, CHO 135 g/L, Fat 36 g/L, Na 1,000 mg/L, K 1,200 mg/L, Mg 280 mg/L, P 870 mg/L, osmolality 330 mOsmol/kg H2O.
Calcium carbonate is specifically formulated for the dietary management of malnutrition and other medical conditions with increased nutritional needs that cannot be met through diet modification alone.
Special Features: Calcium carbonate is isotonic (low osmolality); 100% complex carbohydrate; 20% of fat as MCT; lactose-free; unflavoured.
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Osteoporosis
Hypocalcemia
Dyspepsia
Duodenal Ulcer
Gastric Ulcer
Erosive Esophagitis
Gastroesophageal Reflux Disease
Usual Pediatric Dose for:
Hypocalcemia
Additional dosage information:
Renal Dose Adjustments
Liver Dose Adjustments
Dialysis
Other Comments
Usual Adult Dose for Osteoporosis
2500 to 7500 mg/day orally in 2 to 4 divided doses.
Usual Adult Dose for Hypocalcemia
900 to 2500 mg/day orally in 2 to 4 divided doses. This dose may be adjusted as needed to achieve a normal serum calcium level.
Usual Adult Dose for Dyspepsia
300 to 8000 mg/day orally in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease symptoms of stomach upset.
Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.
Usual Adult Dose for Duodenal Ulcer
1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of calcium carbonate is gastric hypersecretion and acid rebound.
Usual Adult Dose for Gastric Ulcer
1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of calcium carbonate is gastric hypersecretion and acid rebound.
Usual Adult Dose for Erosive Esophagitis
1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents.
Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.
Usual Adult Dose for Gastroesophageal Reflux Disease
1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents.
Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.
Usual Pediatric Dose for Hypocalcemia
Neonatal:
Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium: 50 to 150 mg/kg/day in 4 to 6 divided doses; not to exceed 1 g/day
Usual
Dosage:
Calcium carbonate:
Children 2 to 5 years: Childrens Pepto, Mylanta (R) Childrens: 1 tablet (400 mg calcium carbonate) as symptoms occur; not to exceed 3 tablets/day
Children 6 to 11 years: Childrens Pepto, Mylanta (R) Childrens: 2 tablets (800 mg calcium carbonate) as symptoms occur; not to exceed 6 tablets/day
Children 11 years and older:
Tums (R), Tums (R) E-X: 2 to 4 tablets chewed as symptoms occur; not to exceed 15 tablets [Tums (R)] or 10 tablets [Tums (R) E-X] per day
Tums (R) Ultra: 2 to 3 tablets chewed as symptoms occur; not to exceed 7 tablets per day
Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium:
Children: 45 to 65 mg/kg/day in 4 divided doses
Treatment of hyperphosphatemia in end-stage renal failure: Children and Adults: Dose expressed in mg of calcium carbonate: 1 g with each meal; increase as needed; range: 4 to 7 g/day
Hydrofluoric acid (HF) burns (HF concentration less than 20%):
Topical: Various topical calcium preparations have been used anecdotally for treatment of dermal exposure to HF solutions; calcium carbonate at concentrations ranging from 2.5% to 33% has been used; a topical calcium carbonate preparation must be compounded.
Renal Dose Adjustments
Patients with renal dysfunction have an increased risk of hypercalcemia. Periodically checking the serum calcium level, especially if signs or symptoms of hypercalcemia are detected, is recommended.
The use of calcium carbonate is not indicated for the treatment of hyperphosphatemia in patients with calculated or estimated creatinine clearance equal to or greater than 25 mL/min.
Liver Dose Adjustments
Data not available
Dialysis
Calcium is removed by hemodialysis. To ensure a positive net calcium flux into the patient during dialysis, a dialysate calcium concentration of 3 to 3.5 mEq/L is usually required. Mid-dialysis modest hypercalcemia is not uncommon when this concentration is used.
Calcium is removed by peritoneal dialysis. The standard peritoneal dialysate contains 3.5 mEq/L of calcium (in 1.5% dextrose) to maintain a positive calcium balance and to prevent calcium losses. When higher concentrations of dextrose are used, the net calcium balance may be negative because of a greater convective removal of calcium during ultrafiltration. This counterbalances the diffusion of calcium from the dialysate to the patient.
Other Comments
Dietary reference intake: Dosage is in terms of elemental calcium:
0 to 6 months: Adequate intake: 200 mg/day
7 to 12 months: Adequate intake: 260 mg/day
1 to 3 years: RDA: 700 mg/day
4 to 8 years: RDA: 1000 mg/day
9 to 18 years: RDA: 1300 mg/day
Adults, Female/Male: RDA:
19 to 50 years: 1000 mg/day
51 years and older, females: 1200 mg/day
51 to 70 years, males: 1000 mg/day
Female: Pregnancy/Lactating: RDA: Same as for Adults, Female/Male
Calcium carbonate:
Elemental calcium: 400 mg/1 g (20 mEq calcium/gram)
Approximate equivalent dose: 225 mg of calcium salt
Osteoporosis may be associated with increased serum parathyroid hormone, excessive alcohol intake, tobacco use, inactivity, and certain drugs. Additional factors to consider in males with osteoporosis include hypogonadism and/or age related decreases in serum testosterone. Adequate vitamin D intake and weight bearing exercise (if possible) are recommended.
Each 1 g of calcium carbonate contains 400 mg elemental calcium, or 20 mEq calcium.
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An interaction generally means that one drug may increase or decrease the effect of another drug. Also, the more medications a person takes, the more likely there will be a drug interaction. Antacids do interact with or prevent the absorption of many medications. As a general rule it is best to separate Calcium carbonate use and any other medications by at least 1 hour. When antacids are only taken occasionally, this seldom presents a serious problem. Since there are so many good medications to reduce stomach acid, some of them over-the-counter, it is unusual to require frequent Calcium carbonate use during the day and night.
Interactions with this Calcium carbonate may occur with the following:
* flecainide (Tambocor)
* phenytoin type drugs (Dilantin, Mesantoin, Peganone, Cerebyx)
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation.
Seek medical attention right away if any of these SEVERE side effects occur while taking calcium carbonate (the active ingredient contained in Calcium carbonate)
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; increased urination; loss of appetite; mental or mood changes; nausea; severe or persistent constipation or stomach pain; weakness; vomiting.
Known hypersensitivity reaction to any of the ingredients of Calcium carbonate.
What is Lysine hydrochloride?
Lysine hydrochloride is an essential amino acid. Essential means that it is not produced by the body and therefore it must be taken in either by diet or by taking supplements. Lysine hydrochloride is found in foods such as lentils, red meat, pork, poultry, cod fish, sardines, nuts, eggs, soy beans, brewer's yeast, and dairy products.
Lysine hydrochloride has been used in alternative medicine as an aid to prevent cold sores around the mouth (caused by the herpes simplex virus). This product may make cold sores occur less often and may reduce the number of days a cold sore lasts. Lysine hydrochloride is not a cure for herpes.
Other uses for Lysine hydrochloride include treating metabolic acidosis, improving athletic performance, and helping the body absorb calcium supplements.
Not all uses for Lysine hydrochloride have been approved by the FDA. Lysine hydrochloride should not be used in place of medication prescribed for you by your doctor.
Lysine hydrochloride is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Lysine hydrochloride may also be used for purposes not listed in this product guide
Lysine hydrochloride indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
Supplemental L-Lysine hydrochloride has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Uses of Lysine hydrochloride in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Herpes simplex infections.
Lysine hydrochloride description
L-Lysine hydrochloride (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. L-Lysine hydrochloride is a base, as are arginine and histidine. The ε-amino group often participates in hydrogen bonding and as a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from Lysine hydrochloride by lysyl hydroxylase. O-Glycosylation of Lysine hydrochloride residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Lysine hydrochloride dosage
Oral
Treatment and prophylaxis of herpes simplex
Adult: To treat symptoms: 3,000-9,000 mg/day in divided doses. To prevent recurrences: 500-1,500 mg/day.
Adverse effects associated with the mechanics of retrograde genitourinary procedures include injury to the urethra, bladder, and ureter, and introduction of infection. {03} {06} {31}
Systemic adverse effects, similar to those that occur with direct intravascular injection of the diatrizoate salts, may also occur with intravesical or intraureteral instillation as a result of inadvertent intravascular entry of the contrast solution due to either bladder absorption or pyelorenal backflow. {06} {31}
Systemic adverse effects, although rare, are possible with intrauterine instillation if medium is absorbed systemically after being retained in the uterine cavity or spilled into the peritoneal cavity. {06} {34}
The following side/adverse effects have been selected on the basis of their potential clinical significance (possible signs and symptoms in parentheses where appropriate)—not necessarily inclusive
Hypersensitivity to any component. - Must be used with caution in patients with a history of coronary disease, peripheral vascular disease, severe hypertension, advanced hepatic or renal.- It is contraindicated in patients with active peptic ulcer or gastrointestinal bleeding. -
No association with macrolide antibiotics or beta blockers
What is Magnesium oxide?
Magnesium is a naturally occurring mineral. Magnesium is important for many systems in the body especially the muscles and nerves.
Magnesium oxide is used as a supplement to maintain adequate magnesium in the body.
Magnesium oxide is also used as an Magnesium oxide to treat indigestion, or as a laxative to relieve occasional constipation.
Magnesium oxide may also be used for purposes not listed in this medication guide.
Magnesium oxide indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
Magnesium is a naturally occurring mineral. Magnesium is important for many systems in the body especially the muscles and nerves.
Magnesium oxide is used as a supplement to maintain adequate magnesium in the body.
How should I use Magnesium oxide?
Use magnesium oxide as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take magnesium oxide by mouth with food.
If you also take a bisphosphonate (eg, alendronic acid), digoxin, a quinolone (eg, ciprofloxacin), or a tetracycline (eg, doxycycline), do not take them within 2 to 4 hours before or after taking magnesium oxide. Check with your doctor if you have questions.
If you miss a dose of magnesium oxide and are using it regularly, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use magnesium oxide.
Uses of Magnesium oxide in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
This medication is a mineral supplement used to prevent and treat low amounts of magnesium in the blood. Magnesium is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of magnesium. However, certain situations cause your body to lose magnesium faster than you can replace it from your diet. These situations include treatment with "water pills" (diuretics such as furosemide, hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).
How to use Magnesium oxide
Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.
It is best to take magnesium supplements with a meal to reduce stomach upset and diarrhea unless otherwise directed by the product instructions or your doctor.
Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules and delayed-release/enteric coated tablets or capsules whole. Do not crush or chew extended-release or delayed-release/enteric coated capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
If you are using a liquid product, use a medication measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.
Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much magnesium in the blood can cause serious side effects.
Tell your doctor if symptoms of low magnesium blood levels (e.g., muscle cramps, tiredness, irritability, depression) persist or worsen. If you think you may have a serious medical problem, seek immediate medical attention.
Magnesium oxide description
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an Magnesium oxide and mild laxative and has many nonmedicinal uses. [PubChem]
Magnesium oxide dosage
Dosage Forms
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Hypomagnesemia: Limited data available: Infants, Children, and Adolescents: Dose expressed as elemental magnesium:
Oral: 10 to 20 mg/kg/dose up to 4 times daily; usual adult dose: 300 mg 4 times daily (Kliegman 2007). Note: Achieving optimal magnesium levels using oral therapy may be difficult due to the propensity for magnesium to cause diarrhea: IV replacement may be more appropriate particularly in situations of severe deficit.
Before taking magnesium oxide, talk to your doctor if you are taking
a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others);
a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), enoxacin (Penetrex), norfloxacin (Noroxin), sparfloxacin (Zagam), levofloxacin (Levaquin), lomefloxacin (Maxaquin), grepafloxacin (Raxar), and others;
penicillamine (Cuprimine);
digoxin (Lanoxin, Lanoxicaps); or
nitrofurantoin (Macrodantin, Furadantin, others).
You not be able to take magnesium oxide, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
Drugs other than those listed here can also interact with magnesium oxide. Talk to your doctor and pharmacist before taking any over-the-counter or prescription medicines.
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea.
Seek medical attention right away if any of these SEVERE side effects occur while taking magnesium oxide (the active ingredient contained in Magnesium oxide)
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; nausea; slow reflexes; vomit that looks like coffee grounds.
Do not take magnesium oxide without first talking to your doctor if you have kidney disease.
Before taking magnesium oxide, tell your doctor if you have any other medical conditions, allergies, or if you take other medicines or other herbal/health supplements. Magnesium oxide may not be recommended in some situations.
It is not known whether magnesium oxide will harm an unborn baby. Do not take magnesium oxide without first talking to your doctor if you are pregnant or planning a pregnancy. It is not known whether magnesium oxide will harm an nursing baby. Do not take magnesium oxide without first talking to your doctor if you are breast-feeding a baby.
What is Vitamin D3?
Cholecalciferol is a vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.
Cholecalciferol is used to treat or prevent many conditions caused by a lack of vitamin D, especially conditions of the skin or bones.
Cholecalciferol may also be used for purposes not listed in this medication guide.
Vitamin D3 indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
Vitamin D3 has an important role in energize the intestinal absorption for calcium and phosphor, to regulate their metabolism and balance in blood. It helps bone calcification. Deficiency of vitamin D3 in the body causes deficiency of the calcium in the bone, weakness of its resistance and deformity.
Uses of Vitamin D3 in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Vitamin D3 is used for the prevention and treatment of vitamin D deficiency. Vitamin D3 is important for absorption of calcium in the body. It is also used to prevent bone disorders such as osteomalacia and rickets.
Vitamin D3 description
Vitamin D3 (Vitamin D2) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from cholecalciferol in having a double bond between C22 and C23 and a methyl group at C24.
Vitamin D3 dosage
1 tab daily.
Vitamin D3 interactions
Interactions for vitamin D analogues (Vitamin D2, Vitamin D3, Calcitriol, and Calcidiol)
Cholestyramine
Cholestyramine has been reported to reduce intestinal absorption of fat soluble vitamins; as such it may impair intestinal absorption of any of vitamin D
Phenytoin/Phenobarbital
The coadministration of phenytoin or phenobarbital will not affect plasma concentrations of vitamin D, but may reduce endogenous plasma levels of calcitriol/ergocalcitriol by accelerating metabolism. Since blood level of calcitriol/ergocalcitriol will be reduced, higher doses of Rocaltrol may be necessary if these drugs are administered simultaneously
Thiazides
Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. Some reports have shown that the concomitant administration of thiazides with vitamin D causes hypercalcemia. Therefore, precaution should be taken when coadministration is necessary
Digitalis
Vitamin D dosage must be determined with care in patients undergoing treatment with digitalis, as hypercalcemia in such patients may precipitate cardiac arrhythmias
Ketoconazole
Ketoconazole may inhibit both synthetic and catabolic enzymes of vitamin D. Reductions in serum endogenous vitamin D concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men. However, in vivo drug interaction studies of ketoconazole with vitamin D have not been investigated
Corticosteroids
A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption
Phosphate-Binding Agents
Since vitamin D also has an effect on phosphate transport in the intestine, kidneys and bones, the dosage of phosphate-binding agents must be adjusted in accordance with the serum phosphate concentration
Vitamin D
The coadministration of any of the vitamin D analogues should be avoided as this could create possible additive effects and hypercalcemia
Calcium Supplements
Uncontrolled intake of additional calcium-containing preparations should be avoided
Magnesium
Magnesium-containing preparations (eg, antacids) may cause hypermagnesemia and should therefore not be taken during therapy with vitamin D by patients on chronic renal dialysis.
As well as its needed effects, cholecalciferol (the active ingredient contained in Vitamin D3) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking cholecalciferol, check with your doctor immediately:
Incidence not known:
Cough
difficulty swallowing
dizziness
fast heartbeat
hives or itching
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
skin rash
tightness in the chest
unusual tiredness or weakness
Vitamin D3 contraindications
Contraindications for vitamin D analogues (Vitamin D2, Vitamin D3, Calcitriol, and Calcidiol)
Vitamin D should not be given to patients with hypercalcemia or evidence of vitamin D toxicity. Use of vitamin D in patients with known hypersensitivity to vitamin D (or drugs of the same class) or any of the inactive ingredients is contraindicated.
Zinc sulphate monohydrate indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
Old age, poor diet, prolonged antibiotic therapy, debilitating diseases & special diets.
Uses of Zinc sulphate monohydrate in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
It is indicated for the treatment of acute and persistent diarrhoea in infants and children up to 5 years of age.
Zinc sulphate monohydrate Syrup: Each 5 mL contains zinc gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.
Zinc sulphate monohydrate dosage
Adult & child above 12 yrs: 1 tab daily with or after meals.
Zinc sulphate monohydrate interactions
Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.
Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H2-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.
Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia.
Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and folic acid antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; folic acid may decrease serum-phenytoin concentrations.
There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.
Ascorbic acid may increase the absorption of iron-deficiency states.
Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.
The absorption of zinc may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc supplements reduce the absorption of copper, ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.
Zinc sulphate monohydrate side effects
As Zinc sulphate monohydrate is a nutritional supplement, there are no significant adverse effects expected at recommended doses. However, large doses may cause yellow coloration of the urine due to riboflavin and rarely hypersensitivity reactions due to thiamine and cyanocobalamin and folic acid. Long-term administration of large doses of pyridoxine is associated with the development of severe peripheral neuropathies.
Large doses of ascorbic acid are reported to cause diarrhoea and other gastrointestinal disturbances, hyperoxaluria, haemolysis (in patients with glucose 6-phosphate dehydrogenase deficiency) and the formation of renal calcium oxalate calculi.
The most common side effects of zinc salts include abdominal pain, dyspepsia, nausea, vomiting, diarrhoea and gastric irritation.
Zinc sulphate monohydrate contraindications
Hypersensitivity to any of the ingredients of Zinc sulphate monohydrate.
Active ingredient matches for Calcium carbonate/lysine hydrochloride/magnesium oxide/vitamin D3/zinc sulphate monohydrate:
DailyMed. "MAGNESIUM OXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
DailyMed. "CALCIUM CARBONATE; FAMOTIDINE; MAGNESIUM HYDROXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
DailyMed. "CHOLECALCIFEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
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