Calcium carbonate/vitamin D3/zinc sulphate Uses

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Consists of calcium carbonate, vitamin D3, zinc sulphate

What is Calcium carbonate?

Antacids are taken by mouth to relieve heartburn, sour stomach, or acid indigestion. They work by neutralizing excess stomach acid. Some Calcium carbonate combinations also contain simethicone, which may relieve the symptoms of excess gas. Antacids alone or in combination with simethicone may also be used to treat the symptoms of stomach or duodenal ulcers.

With larger doses than those used for the Calcium carbonate effect, magnesium hydroxide (magnesia) and magnesium oxide antacids produce a laxative effect. The information that follows applies only to their use as an Calcium carbonate.

Some antacids, like aluminum carbonate and aluminum hydroxide, may be prescribed with a low-phosphate diet to treat hyperphosphatemia (too much phosphate in the blood). Aluminum carbonate and aluminum hydroxide may also be used with a low-phosphate diet to prevent the formation of some kinds of kidney stones. Aluminum hydroxide may also be used for other conditions as determined by your doctor.

These medicines are available without a prescription. However, your doctor may have special instructions on the proper use and dose of these medicines for your medical problem.

Calcium carbonate indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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this Calcium carbonate is useful for the temporary relief of occasional indigestion and heartburn. Frequent, daily or nightly symptoms usually mean a more serious problem. Antacids by themselves do not correct these problems. The medications that are now available to treat acid problems are generally superior to antacids.

The second and more important use of calcium carbonate is as a source of calcium, necessary for bones and teeth and to prevent osteoporosis. A quart of milk contains about 1500 mg of calcium which is about what you need. Otherwise this or a similar calcium preparation can be taken.

How should I use Calcium carbonate?

Use calcium carbonate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use calcium carbonate.

Uses of Calcium carbonate in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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This medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).

Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Having the right amount of calcium is important for building and keeping strong bones.

How to use Calcium carbonate

Take this medication by mouth with food. If your product contains calcium citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using the chewable product, chew it well before swallowing.

If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Do not chew or swallow the tablet whole.

If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. Do not use a household spoon. If the liquid product is a suspension, shake the bottle well before each dose.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.

If you think you may have a serious medical problem, seek immediate medical attention.

Calcium carbonate description

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Each Calcium carbonate milk powd contains: Energy Density 1 kCal/mL. Energy Distribution: Protein: Fat: CHO 13:37:50, Protein 32.5 g/L, CHO 125.7 g/L, Fat 42 g/L, Na 500 mg/L, K 1,250 mg/L, Mg 200 mg/L, P 500 mg/L, osmolality 300 mOsmol/kg H2O.

Each Calcium carbonate oral liqd (ready-to-drink) contains: Energy Density 1 kCal/mL. Energy Distribution: Protein: Fat: CHO 14:32:54, Protein 35 g/L, CHO 135 g/L, Fat 36 g/L, Na 1,000 mg/L, K 1,200 mg/L, Mg 280 mg/L, P 870 mg/L, osmolality 330 mOsmol/kg H2O.

Calcium carbonate is specifically formulated for the dietary management of malnutrition and other medical conditions with increased nutritional needs that cannot be met through diet modification alone.

Special Features: Calcium carbonate is isotonic (low osmolality); 100% complex carbohydrate; 20% of fat as MCT; lactose-free; unflavoured.

Calcium carbonate dosage

Calcium Carbonate Dosage

Applies to the following strength(s): 650 mg; 600 mg; 1250 mg/5 mL; 1250 mg; 1000 mg; 500 mg; 400 mg; base 500 mg; 750 mg; 900 mg; 648 mg; 420 mg; 250 mg; 550 mg; 1177 mg; 850 mg; 400 mg/5 mL; 350 mg; 1.5 g; 1 g; 300 mg; 450 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Osteoporosis

2500 to 7500 mg/day orally in 2 to 4 divided doses.

Usual Adult Dose for Hypocalcemia

900 to 2500 mg/day orally in 2 to 4 divided doses. This dose may be adjusted as needed to achieve a normal serum calcium level.

Usual Adult Dose for Dyspepsia

300 to 8000 mg/day orally in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease symptoms of stomach upset.

Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Adult Dose for Duodenal Ulcer

1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of calcium carbonate is gastric hypersecretion and acid rebound.

Usual Adult Dose for Gastric Ulcer

1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of calcium carbonate is gastric hypersecretion and acid rebound.

Usual Adult Dose for Erosive Esophagitis

1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents.

Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Adult Dose for Gastroesophageal Reflux Disease

1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents.

Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Pediatric Dose for Hypocalcemia

Neonatal:

Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium: 50 to 150 mg/kg/day in 4 to 6 divided doses; not to exceed 1 g/day

Usual

Dosage:

Calcium carbonate:

Children 2 to 5 years: Childrens Pepto, Mylanta (R) Childrens: 1 tablet (400 mg calcium carbonate) as symptoms occur; not to exceed 3 tablets/day

Children 6 to 11 years: Childrens Pepto, Mylanta (R) Childrens: 2 tablets (800 mg calcium carbonate) as symptoms occur; not to exceed 6 tablets/day

Children 11 years and older:

Tums (R), Tums (R) E-X: 2 to 4 tablets chewed as symptoms occur; not to exceed 15 tablets [Tums (R)] or 10 tablets [Tums (R) E-X] per day

Tums (R) Ultra: 2 to 3 tablets chewed as symptoms occur; not to exceed 7 tablets per day

Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium:

Children: 45 to 65 mg/kg/day in 4 divided doses

Treatment of hyperphosphatemia in end-stage renal failure: Children and Adults: Dose expressed in mg of calcium carbonate: 1 g with each meal; increase as needed; range: 4 to 7 g/day

Hydrofluoric acid (HF) burns (HF concentration less than 20%):

Topical: Various topical calcium preparations have been used anecdotally for treatment of dermal exposure to HF solutions; calcium carbonate at concentrations ranging from 2.5% to 33% has been used; a topical calcium carbonate preparation must be compounded.

Renal Dose Adjustments

Patients with renal dysfunction have an increased risk of hypercalcemia. Periodically checking the serum calcium level, especially if signs or symptoms of hypercalcemia are detected, is recommended.

The use of calcium carbonate is not indicated for the treatment of hyperphosphatemia in patients with calculated or estimated creatinine clearance equal to or greater than 25 mL/min.

Liver Dose Adjustments

Data not available

Dialysis

Calcium is removed by hemodialysis. To ensure a positive net calcium flux into the patient during dialysis, a dialysate calcium concentration of 3 to 3.5 mEq/L is usually required. Mid-dialysis modest hypercalcemia is not uncommon when this concentration is used.

Calcium is removed by peritoneal dialysis. The standard peritoneal dialysate contains 3.5 mEq/L of calcium (in 1.5% dextrose) to maintain a positive calcium balance and to prevent calcium losses. When higher concentrations of dextrose are used, the net calcium balance may be negative because of a greater convective removal of calcium during ultrafiltration. This counterbalances the diffusion of calcium from the dialysate to the patient.

Other Comments

Dietary reference intake: Dosage is in terms of elemental calcium:

0 to 6 months: Adequate intake: 200 mg/day

7 to 12 months: Adequate intake: 260 mg/day

1 to 3 years: RDA: 700 mg/day

4 to 8 years: RDA: 1000 mg/day

9 to 18 years: RDA: 1300 mg/day

Adults, Female/Male: RDA:

19 to 50 years: 1000 mg/day

51 years and older, females: 1200 mg/day

51 to 70 years, males: 1000 mg/day

Female: Pregnancy/Lactating: RDA: Same as for Adults, Female/Male

Calcium carbonate:

Elemental calcium: 400 mg/1 g (20 mEq calcium/gram)

Approximate equivalent dose: 225 mg of calcium salt

Osteoporosis may be associated with increased serum parathyroid hormone, excessive alcohol intake, tobacco use, inactivity, and certain drugs. Additional factors to consider in males with osteoporosis include hypogonadism and/or age related decreases in serum testosterone. Adequate vitamin D intake and weight bearing exercise (if possible) are recommended.

Each 1 g of calcium carbonate contains 400 mg elemental calcium, or 20 mEq calcium.

More about calcium carbonate

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Calcium carbonate interactions

See also:
What other drugs will affect Calcium carbonate?

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An interaction generally means that one drug may increase or decrease the effect of another drug. Also, the more medications a person takes, the more likely there will be a drug interaction. Antacids do interact with or prevent the absorption of many medications. As a general rule it is best to separate Calcium carbonate use and any other medications by at least 1 hour. When antacids are only taken occasionally, this seldom presents a serious problem. Since there are so many good medications to reduce stomach acid, some of them over-the-counter, it is unusual to require frequent Calcium carbonate use during the day and night.

Interactions with this Calcium carbonate may occur with the following:

* flecainide (Tambocor)

* phenytoin type drugs (Dilantin, Mesantoin, Peganone, Cerebyx)

* iron (Feosol, ferrous sulfate, Nu-Iron)

* quinidine (Quinidex, Quinaglute)

* aspirin, salicylates

* tetracycline (Sumycin, Tetracyn)

Calcium carbonate side effects

See also:
What are the possible side effects of Calcium carbonate?

Applies to calcium carbonate: tablets

Other dosage forms:

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation.

Seek medical attention right away if any of these SEVERE side effects occur while taking calcium carbonate (the active ingredient contained in Calcium carbonate)

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; increased urination; loss of appetite; mental or mood changes; nausea; severe or persistent constipation or stomach pain; weakness; vomiting.

Calcium carbonate contraindications

See also:
What is the most important information I should know about Calcium carbonate?

Known hypersensitivity reaction to any of the ingredients of Calcium carbonate.

What is Vitamin D3?

Cholecalciferol is a vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Cholecalciferol is used to treat or prevent many conditions caused by a lack of vitamin D, especially conditions of the skin or bones.

Cholecalciferol may also be used for purposes not listed in this medication guide.

Vitamin D3 indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Vitamin D3 has an important role in energize the intestinal absorption for calcium and phosphor, to regulate their metabolism and balance in blood. It helps bone calcification. Deficiency of vitamin D3 in the body causes deficiency of the calcium in the bone, weakness of its resistance and deformity.

Uses of Vitamin D3 in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Vitamin D3 is used for the prevention and treatment of vitamin D deficiency. Vitamin D3 is important for absorption of calcium in the body. It is also used to prevent bone disorders such as osteomalacia and rickets.

Vitamin D3 description

Vitamin D3 (Vitamin D2) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from cholecalciferol in having a double bond between C22 and C23 and a methyl group at C24.

Vitamin D3 dosage

1 tab daily.

Vitamin D3 interactions

Interactions for vitamin D analogues (Vitamin D2, Vitamin D3, Calcitriol, and Calcidiol)

Cholestyramine

Cholestyramine has been reported to reduce intestinal absorption of fat soluble vitamins; as such it may impair intestinal absorption of any of vitamin D

Phenytoin/Phenobarbital

The coadministration of phenytoin or phenobarbital will not affect plasma concentrations of vitamin D, but may reduce endogenous plasma levels of calcitriol/ergocalcitriol by accelerating metabolism. Since blood level of calcitriol/ergocalcitriol will be reduced, higher doses of Rocaltrol may be necessary if these drugs are administered simultaneously

Thiazides

Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. Some reports have shown that the concomitant administration of thiazides with vitamin D causes hypercalcemia. Therefore, precaution should be taken when coadministration is necessary

Digitalis

Vitamin D dosage must be determined with care in patients undergoing treatment with digitalis, as hypercalcemia in such patients may precipitate cardiac arrhythmias

Ketoconazole

Ketoconazole may inhibit both synthetic and catabolic enzymes of vitamin D. Reductions in serum endogenous vitamin D concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men. However, in vivo drug interaction studies of ketoconazole with vitamin D have not been investigated

Corticosteroids

A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption

Phosphate-Binding Agents

Since vitamin D also has an effect on phosphate transport in the intestine, kidneys and bones, the dosage of phosphate-binding agents must be adjusted in accordance with the serum phosphate concentration

Vitamin D

The coadministration of any of the vitamin D analogues should be avoided as this could create possible additive effects and hypercalcemia

Calcium Supplements

Uncontrolled intake of additional calcium-containing preparations should be avoided

Magnesium

Magnesium-containing preparations (eg, antacids) may cause hypermagnesemia and should therefore not be taken during therapy with vitamin D by patients on chronic renal dialysis.

Vitamin D3 side effects

Applies to cholecalciferol: oral capsule, oral capsule liquid filled, oral solution, oral tablet, oral tablet chewable, oral wafer

As well as its needed effects, cholecalciferol (the active ingredient contained in Vitamin D3) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking cholecalciferol, check with your doctor immediately:

Incidence not known:

Vitamin D3 contraindications

Contraindications for vitamin D analogues (Vitamin D2, Vitamin D3, Calcitriol, and Calcidiol)

Vitamin D should not be given to patients with hypercalcemia or evidence of vitamin D toxicity. Use of vitamin D in patients with known hypersensitivity to vitamin D (or drugs of the same class) or any of the inactive ingredients is contraindicated.

Zinc sulphate indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues.

Zinc sulfate is used to treat and to prevent zinc deficiency. This medication may also be used to promote wound healing.

Zinc sulphate description

Zinc sulphate Capsule: Each capsule contains zinc sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, vitamin B12 (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, folic acid 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc sulphate Syrup: Each 5 mL contains zinc gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.

Zinc sulphate dosage

Childn 6 mth-5 yr 5 mL once daily for 10 days. Infant <6 mth 2.5 mL once daily for 10 days. Continue therapy even if diarrhea has stopped.

Zinc sulphate interactions

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: penicillamine, quinolone antibiotics (e.g., ciprofloxacin), tetracyclines, phosphorus containing products

Zinc sulphate side effects

Nausea, stomach upset, heartburn may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: fever, chills, sore throat, sores in mouth, unusual tiredness, weakness

Zinc sulphate contraindications

unknown.

Active ingredient matches for Calcium carbonate/vitamin D3/zinc sulphate:

Calcium carbonate/vitamin D3/zinc sulphate


References

  1. DailyMed. "CALCIUM CARBONATE; FAMOTIDINE; MAGNESIUM HYDROXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CHOLECALCIFEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DailyMed. "CALCIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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