Calibon Z Tablet Actions

How do you administer this medicine?
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Actions of Calibon Z Tablet in details

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Calibon Z Tablet is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. It also inhibits the action of pepsin by increasing the pH and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (HCO3-) and prostaglandins. Neutralization of hydrochloric acid results in the formation of calcium chloride, carbon dioxide and water. Approximately 90% of calcium chloride is converted to insoluble calcium salts (e.g. Calibon Z Tablet and calcium phosphate).

How should I take Calibon Z Tablet?

Take Calibon Z Tablet exactly as directed by your doctor or follow the directions on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Swallow the Calibon Z Tablet tablets and capsules with a full glass of water.

Chew the chewable forms of Calibon Z Tablet completely before swallowing.

Use the Calibon Z Tablet powder as directed. Allow the powder to dissolve completely, then consume the mixture.

Shake the Calibon Z Tablet suspension well before measuring a dose. To ensure that you get the correct dose, use a dose-measuring spoon or cup, not a regular table spoon to measure the liquid. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take calcium with meals to increase its absorption by the body, unless otherwise directed by your doctor.

Store Calibon Z Tablet at room temperature away from moisture and heat.

Calibon Z Tablet administration

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Oral: Administer with food. Doses >600 mg (

elemental calcium) per day should be divided for optimal absorption (AACE [Camacho 2016]).

Capsules may be swallowed whole or opened and the contents mixed with food or drink.

Calibon Z Tablet pharmacology

Gastric-peptic disease occurs as a result of an imbalance between protective factors, such as mucus, bicarbonate, and prostaglandin secretion, and aggressive factors, such as hydrochloric acid, pepsin, and Helicobacter pylori (H. pylori). Antacids work by restoring acid-base balance, attenuating the pepsin activity and increasing bicarbonate and prostaglandin secretion. The acid-neutralizing capacity of Calibon Z Tablet is 58 mEq/15 ml. When used as a nutritional supplement, Calibon Z Tablet acts by directly increasing calcium stores within the body.

References

  1. DailyMed. "CALCIUM CARBONATE; FAMOTIDINE; MAGNESIUM HYDROXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CALCIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. NCIt. "Calcium Carbonate: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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