Carcal Uses

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Consists of Calcitriol, Calcium Carbonate

What is Calcitriol (Carcal)?

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.

Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.

Ergocalciferol is the form of vitamin D used in vitamin supplements.

Some conditions may increase your need for vitamin D. These include:

In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.

Alfacalcidol, calcifediol, Calcitriol (Carcal), and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and Calcitriol (Carcal) are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.

Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.

Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of ergocalciferol and all strengths of alfacalcidol, calcifediol, Calcitriol (Carcal), and dihydrotachysterol are available only with your doctor's prescription. Other strengths of ergocalciferol are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.

Calcitriol (Carcal) indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Predialysis Patients

Calcitriol (Carcal) (Calcitriol (Carcal)) is indicated in the management of secondary hyperparathyroidism and resultant metabolic bone disease in patients with moderate to severe chronic renal failure (Ccr 15 to 55 mL/min) not yet on dialysis. In children, the creatinine clearance value must be corrected for a surface area of 1.73 square meters. A serum iPTH level of ≥ 100 pg/mL is strongly suggestive of secondary hyperparathyroidism.

Dialysis Patients

Calcitriol (Carcal) (Calcitriol (Carcal)) is indicated in the management of hypocalcemia and the resultant metabolic bone disease in patients undergoing chronic renal dialysis. In these patients, Calcitriol (Carcal) (Calcitriol (Carcal)) administration enhances calcium absorption, reduces serum alkaline phosphatase levels, and may reduce elevated parathyroid hormone levels and the histological manifestations of osteitis fibrosa cystica and defective mineralization.

Hypoparathyroidism Patients

Calcitriol (Carcal) (Calcitriol (Carcal)) is also indicated in the management of hypocalcemia and its clinical manifestations in patients with postsurgical hypoparathyroidism, idiopathic hypoparathyroidism, and pseudohypoparathyroidism.

How should I use Calcitriol (Carcal)?

Use Calcitriol (Carcal) solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Calcitriol (Carcal) solution.

Uses of Calcitriol (Carcal) in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Calcitriol (Carcal) is a man-made active form of vitamin D. Most people get enough vitamin D from exposure to the sun and from fortified food products (e.g., dairy products, vitamins). Vitamin D helps control parathyroid hormone and the levels of certain minerals (e.g., calcium, phosphorus) that are needed for building and keeping strong bones.

Before regular vitamin D can be used by the body, it needs to be changed to the active form by the liver and kidneys. Calcitriol (Carcal) is used in patients with kidney disease who can't make enough of the active form of Vitamin D. This medication is also used to prevent and treat certain types of calcium/phosphorus/parathyroid problems that can happen with long-term kidney dialysis or hypoparathyroidism. Calcitriol (Carcal) is usually used along with specific diet recommendations and sometimes other medications.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used to treat and prevent certain bone diseases (rickets, osteomalacia) when regular vitamin D does not work.

How to use Calcitriol (Carcal)

Take this medication by mouth with or without food, usually once daily or as directed by your doctor. If you are using the liquid form, measure your dose with a special measuring spoon or device. Do not use a normal household spoon since you may not get the correct dose.

Dosage is based on your medical condition and response to therapy. Your doctor may start you on a low dose and adjust the dose slowly to find the best dose for you. Follow your doctor's directions carefully. Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day.

It is very important to follow the diet recommended by your doctor to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins (e.g., calcium, vitamin D) unless ordered by your doctor.

Certain medications (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat) can decrease the absorption of vitamin D. Therefore, separate your doses of these medications as far as possible from your doses of Calcitriol (Carcal) (at least 2 hours apart, longer if possible). It may be easiest to take Calcitriol (Carcal) at bedtime if you are also taking these other medications. Ask your doctor or pharmacist about finding a good dosing schedule that will work with all your medications.

Calcitriol (Carcal) description

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Each mL of ampoule of solution for injection contains the following excipients: Polysorbate 20 4 mg, sodium chloride 1.5 mg, sodium ascorbate 10 mg, anhydrous dibasic sodium phosphate 7.6 mg, monobasic sodium phosphate monohydrate 1.8 mg and disodium edetate dihydrate 1.1 mg. It has a pH of 7.2 (6.5-8). Calcitriol (Carcal) does not contain a preservative.

Calcitriol (Carcal) is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol. Its molecular formula is C27H44O3.

The other names frequently used are 1α,25-dihydroxycholecalciferol; 1α,25-dihydroxy-vitamin D3; 1,25-DHCC; 1,25(OH)2D3; and 1,25-diOHC.

Calcitriol (Carcal) is a colorless, crystalline compound which occurs naturally in humans. It is soluble in organic solvents but relatively insoluble in water.

Calcitriol (Carcal) dosage

The optimal daily dose of Calcitriol (Carcal) (Calcitriol (Carcal)) must be carefully determined for each patient. Calcitriol (Carcal) (Calcitriol (Carcal)) can be administered orally either as a capsule (0.25 mcg or 0.50 mcg) or as an oral solution (1 mcg/mL). Calcitriol (Carcal) (Calcitriol (Carcal)) therapy should always be started at the lowest possible dose and should not be increased without careful monitoring of serum calcium.

The effectiveness of Calcitriol (Carcal) (Calcitriol (Carcal)) therapy is predicated on the assumption that each patient is receiving an adequate but not excessive daily intake of calcium. Patients are advised to have a dietary intake of calcium at a minimum of 600 mg daily. The U.S. RDA for calcium in adults is 800 mg to 1200 mg. To ensure that each patient receives an adequate daily intake of calcium, the physician should either prescribe a calcium supplement or instruct the patient in proper dietary measures.

Because of improved calcium absorption from the gastrointestinal tract, some patients on Calcitriol (Carcal) (Calcitriol (Carcal)) may be maintained on a lower calcium intake. Patients who tend to develop hypercalcemia may require only low doses of calcium or no supplementation at all.

During the titration period of treatment with Calcitriol (Carcal) (Calcitriol (Carcal)), serum calcium levels should be checked at least twice weekly. When the optimal dosage of Calcitriol (Carcal) (Calcitriol (Carcal)) has been determined, serum calcium levels should be checked every month (or as given below for individual indications). Samples for serum calcium estimation should be taken without a tourniquet.

Dialysis Patients

The recommended initial dose of Calcitriol (Carcal) (Calcitriol (Carcal)) is 0.25 mcg/day. If a satisfactory response in the biochemical parameters and clinical manifestations of the disease state is not observed, dosage may be increased by 0.25 mcg/day at 4 to 8 week intervals. During this titration period, serum calcium levels should be obtained at least twice weekly, and if hypercalcemia is noted, the drug should be immediately discontinued until normocalcemia ensues. Phosphorus, magnesium, and alkaline phosphatase should be determined periodically.

Patients with normal or only slightly reduced serum calcium levels may respond to Calcitriol (Carcal) (Calcitriol (Carcal)) doses of 0.25 mcg every other day. Most patients undergoing hemodialysis respond to doses between 0.5 and 1 mcg/day.

Oral Calcitriol (Carcal) (Calcitriol (Carcal)) may normalize plasma ionized calcium in some uremic patients, yet fail to suppress parathyroid hyperfunction. In these individuals with autonomous parathyroid hyperfunction, oral Calcitriol (Carcal) (Calcitriol (Carcal)) may be useful to maintain normocalcemia, but has not been shown to be adequate treatment for hyperparathyroidism.

Hypoparathyroidism

The recommended initial dosage of Calcitriol (Carcal) (Calcitriol (Carcal)) is 0.25 mcg/day given in the morning. If a satisfactory response in the biochemical parameters and clinical manifestations of the disease is not observed, the dose may be increased at 2-to 4-week intervals. During the dosage titration period, serum calcium levels should be obtained at least twice weekly and, if hypercalcemia is noted, Calcitriol (Carcal) (Calcitriol (Carcal)) should be immediately discontinued until normocalcemia ensues. Careful consideration should also be given to lowering the dietary calcium intake. Serum calcium, phosphorus, and 24-hour urinary calcium should be determined periodically.

Most adult patients and pediatric patients age 6 years and older have responded to dosages in the range of 0.5 mcg to 2 mcg daily. Pediatric patients in the 1 to 5 year age group with hypoparathyroidism have usually been given 0.25 mcg to 0.75 mcg daily. The number of treated patients with pseudohypoparathyroidism less than 6 years of age is too small to make dosage recommendations.

Malabsorption is occasionally noted in patients with hypoparathyroidism; hence, larger doses of Calcitriol (Carcal) (Calcitriol (Carcal)) may be needed.

Predialysis Patients

The recommended initial dosage of Calcitriol (Carcal) (Calcitriol (Carcal)) is 0.25 mcg/day in adults and pediatric patients 3 years of age and older. This dosage may be increased if necessary to 0.5 mcg/day.

For pediatric patients less than 3 years of age, the recommended initial dosage of Calcitriol (Carcal) (Calcitriol (Carcal)) is 10 to 15 ng/kg/day.

How supplied

Capsules: 0.25 mcg Calcitriol (Carcal) in soft gelatin, light orange, oval capsules, imprinted with Calcitriol (Carcal) (Calcitriol (Carcal)) 0.25 ROCHE; bottles of 30 (NDC 0004-0143-23), and bottles of 100 (NDC 0004-0143-01).

Capsules: 0.5 mcg Calcitriol (Carcal) in soft gelatin, dark orange, oblong capsules, imprinted with Calcitriol (Carcal) (Calcitriol (Carcal)) 0.5 ROCHE; bottles of 100 (NDC 0004-0144-01).

Oral Solution

: a clear, colorless to pale yellow oral solution containing 1 mcg/mL of Calcitriol (Carcal); each amber glass bottle of 15 mL of oral solution supplied with 20 single-use, graduated oral dispensers (NDC 0004-9115-00).

Calcitriol (Carcal) (Calcitriol (Carcal)) Capsules and

Oral Solution should be protected from light.

Store at 59° to 86° F (15° to 30° C).

Distributed by: Roche Laboratories Inc., 340 Nutley Street, New Jersey, NJ 07110-1199. Revised: July 2004. FDA Rev date: 7/7/2004

Calcitriol (Carcal) interactions

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What other drugs will affect Calcitriol (Carcal)?

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Cholestyramine:

Cholestyramine has been reported to reduce intestinal absorption of fat-soluble vitamins; as such it may impair intestinal absorption of Calcitriol (Carcal).

Phenytoin/Phenobarbital:

The coadministration of phenytoin or phenobarbital will not affect plasma concentrations of Calcitriol (Carcal), but may reduce endogenous plasma levels of 25(OH)D3 by accelerating metabolism. Since blood level of Calcitriol (Carcal) will be reduced, higher doses of Calcitriol (Carcal) may be necessary if these drugs are administered simultaneously.

Thiazides:

Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. Some reports have shown that the concomitant administration of thiazides with Calcitriol (Carcal) causes hypercalcemia. Therefore, precaution should be taken when coadministration is necessary.

Digitalis:

Calcitriol (Carcal) dosage must be determined with care in patients undergoing treatment with digitalis, as hypercalcemia in such patients may precipitate cardiac arrhythmias.

Ketoconazole:

Ketoconazole may inhibit both synthetic and catabolic enzymes of Calcitriol (Carcal). Reductions in serum endogenous Calcitriol (Carcal) concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men. However, in vivo drug interaction studies of ketoconazole with Calcitriol (Carcal) have not been investigated.

Corticosteroids:

A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption.

Phosphate-Binding Agents:

Since Calcitriol (Carcal) also has an effect on phosphate transport in the intestine, kidneys and bones, the dosage of phosphate-binding agents must be adjusted in accordance with the serum phosphate concentration.

Vitamin D:

Since Calcitriol (Carcal) is the most potent active metabolite of vitamin D3, pharmacological doses of vitamin D and its derivatives should be withheld during treatment with Calcitriol (Carcal) to avoid possible additive effects and hypercalcemia.

Calcium Supplements:

Uncontrolled intake of additional calcium-containing preparations should be avoided.

Magnesium:

Magnesium-containing preparations (e.g., antacids) may cause hypermagnesemia and should therefore not be taken during therapy with Calcitriol (Carcal) by patients on chronic renal dialysis.

Calcitriol (Carcal) side effects

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What are the possible side effects of Calcitriol (Carcal)?

Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rate observed in practice.

Clinical Studies Experience

Calcitriol (Carcal) Ointment was studied in two vehicle-controlled studies (419 subjects), and in one open label study (324 subjects). The table below describes exposure to Calcitriol (Carcal) Ointment in 743 subjects, including 239 exposed for 6 months and 116 exposed for one year.

Four hundred and nineteen subjects were treated with Calcitriol (Carcal) Ointment twice daily for 8 weeks. The population included subjects ages 13 to 87, males (284) and females (135), Caucasians (372) and non-Caucasians (47); with mild (105) to moderate (313) chronic plaque psoriasis.

Among subjects having laboratory monitoring, hypercalcemia was observed in 24% (18/74) of subjects exposed to active drug and in 16% (13/79) of subjects exposed to vehicle, however the elevation were less than 10% above the upper limit of normal

The open label study enrolled 324 subjects with psoriasis who were then treated for up to 52 weeks. Adverse events reported at a rate of greater than or equal to 3% of subjects treated with Calcitriol (Carcal) Ointment were lab test abnormality (8%), urine abnormality (4%), psoriasis (4%), hyperciuria (3%), and pruritus (3%). Kidney stones were reported in 3 subjects and confirmed in two.

Postmarketing Experience

The following adverse reactions have been identified during the world-wide post-approval use of Calcitriol (Carcal) Ointment: acute blistering dermatitis, erythema, pruritus, skin burning sensation, and skin discomfort. Because these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Calcitriol (Carcal) contraindications

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What is the most important information I should know about Calcitriol (Carcal)?

You should not use this medication if you have a severe form of psoriasis (with pus, skin peeling, severe redness).

Before using Calcitriol (Carcal) topical, tell your doctor if you have low or high levels of calcium in your blood, a calcium disorder or metabolic imbalance, or if you are receiving UV light treatments (phototherapy) for your psoriasis.

Tell your doctor about all other medicines you are using to treat psoriasis. Also tell your doctor if you are taking a diuretic (water pill) or vitamin or mineral supplements that contain calcium or vitamin D.

Calcitriol (Carcal) topical is for use only on areas of psoriasis. Avoid getting it on healthy skin areas. Calcitriol (Carcal) topical should not be applied to the face or the vaginal area.

Stop using this medication and call your doctor if you have a serious side effect such as blistering or severe redness, itching, or other irritation of treated skin.

Using Calcitriol (Carcal) topical can affect your body's ability to metabolize calcium. This can result in high levels of calcium in your blood (hypercalcemia). Symptoms of this condition include nausea, loss of appetite, constipation, increased thirst and urination, muscle weakness, confusion, and feeling tired or restless. Call your doctor if you have any of these symptoms.

What is Calcium Carbonate (Carcal)?

Antacids are taken by mouth to relieve heartburn, sour stomach, or acid indigestion. They work by neutralizing excess stomach acid. Some Calcium Carbonate (Carcal) combinations also contain simethicone, which may relieve the symptoms of excess gas. Antacids alone or in combination with simethicone may also be used to treat the symptoms of stomach or duodenal ulcers.

With larger doses than those used for the Calcium Carbonate (Carcal) effect, magnesium hydroxide (magnesia) and magnesium oxide antacids produce a laxative effect. The information that follows applies only to their use as an Calcium Carbonate (Carcal).

Some antacids, like aluminum carbonate and aluminum hydroxide, may be prescribed with a low-phosphate diet to treat hyperphosphatemia (too much phosphate in the blood). Aluminum carbonate and aluminum hydroxide may also be used with a low-phosphate diet to prevent the formation of some kinds of kidney stones. Aluminum hydroxide may also be used for other conditions as determined by your doctor.

These medicines are available without a prescription. However, your doctor may have special instructions on the proper use and dose of these medicines for your medical problem.

Calcium Carbonate (Carcal) indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

this Calcium Carbonate (Carcal) is useful for the temporary relief of occasional indigestion and heartburn. Frequent, daily or nightly symptoms usually mean a more serious problem. Antacids by themselves do not correct these problems. The medications that are now available to treat acid problems are generally superior to antacids.

The second and more important use of Calcium Carbonate (Carcal) is as a source of calcium, necessary for bones and teeth and to prevent osteoporosis. A quart of milk contains about 1500 mg of calcium which is about what you need. Otherwise this or a similar calcium preparation can be taken.

How should I use Calcium Carbonate (Carcal)?

Use Calcium Carbonate (Carcal) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Calcium Carbonate (Carcal).

Uses of Calcium Carbonate (Carcal) in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

This medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).

Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Having the right amount of calcium is important for building and keeping strong bones.

How to use Calcium Carbonate (Carcal)

Take this medication by mouth with food. If your product contains calcium citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using the chewable product, chew it well before swallowing.

If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Do not chew or swallow the tablet whole.

If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. Do not use a household spoon. If the liquid product is a suspension, shake the bottle well before each dose.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.

If you think you may have a serious medical problem, seek immediate medical attention.

Calcium Carbonate (Carcal) description

Each Calcium Carbonate (Carcal) milk powd contains: Energy Density 1 kCal/mL. Energy Distribution: Protein: Fat: CHO 13:37:50, Protein 32.5 g/L, CHO 125.7 g/L, Fat 42 g/L, Na 500 mg/L, K 1,250 mg/L, Mg 200 mg/L, P 500 mg/L, osmolality 300 mOsmol/kg H2O.

Each Calcium Carbonate (Carcal) oral liqd (ready-to-drink) contains: Energy Density 1 kCal/mL. Energy Distribution: Protein: Fat: CHO 14:32:54, Protein 35 g/L, CHO 135 g/L, Fat 36 g/L, Na 1,000 mg/L, K 1,200 mg/L, Mg 280 mg/L, P 870 mg/L, osmolality 330 mOsmol/kg H2O.

Calcium Carbonate (Carcal) is specifically formulated for the dietary management of malnutrition and other medical conditions with increased nutritional needs that cannot be met through diet modification alone.

Special Features: Calcium Carbonate (Carcal) is isotonic (low osmolality); 100% complex carbohydrate; 20% of fat as MCT; lactose-free; unflavoured.

Calcium Carbonate (Carcal) dosage

Calcium Carbonate (Carcal) Dosage

Applies to the following strength(s): 650 mg; 600 mg; 1250 mg/5 mL; 1250 mg; 1000 mg; 500 mg; 400 mg; base 500 mg; 750 mg; 900 mg; 648 mg; 420 mg; 250 mg; 550 mg; 1177 mg; 850 mg; 400 mg/5 mL; 350 mg; 1.5 g; 1 g; 300 mg; 450 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Osteoporosis

2500 to 7500 mg/day orally in 2 to 4 divided doses.

Usual Adult Dose for Hypocalcemia

900 to 2500 mg/day orally in 2 to 4 divided doses. This dose may be adjusted as needed to achieve a normal serum calcium level.

Usual Adult Dose for Dyspepsia

300 to 8000 mg/day orally in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease symptoms of stomach upset.

Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Adult Dose for Duodenal Ulcer

1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of Calcium Carbonate (Carcal) is gastric hypersecretion and acid rebound.

Usual Adult Dose for Gastric Ulcer

1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of Calcium Carbonate (Carcal) is gastric hypersecretion and acid rebound.

Usual Adult Dose for Erosive Esophagitis

1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents.

Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Adult Dose for Gastroesophageal Reflux Disease

1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents.

Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Pediatric Dose for Hypocalcemia

Neonatal:

Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium: 50 to 150 mg/kg/day in 4 to 6 divided doses; not to exceed 1 g/day

Usual

Dosage:

Calcium Carbonate (Carcal):

Children 2 to 5 years: Childrens Pepto, Mylanta (R) Childrens: 1 tablet (400 mg Calcium Carbonate (Carcal)) as symptoms occur; not to exceed 3 tablets/day

Children 6 to 11 years: Childrens Pepto, Mylanta (R) Childrens: 2 tablets (800 mg Calcium Carbonate (Carcal)) as symptoms occur; not to exceed 6 tablets/day

Children 11 years and older:

Tums (R), Tums (R) E-X: 2 to 4 tablets chewed as symptoms occur; not to exceed 15 tablets [Tums (R)] or 10 tablets [Tums (R) E-X] per day

Tums (R) Ultra: 2 to 3 tablets chewed as symptoms occur; not to exceed 7 tablets per day

Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium:

Children: 45 to 65 mg/kg/day in 4 divided doses

Treatment of hyperphosphatemia in end-stage renal failure: Children and Adults: Dose expressed in mg of Calcium Carbonate (Carcal): 1 g with each meal; increase as needed; range: 4 to 7 g/day

Hydrofluoric acid (HF) burns (HF concentration less than 20%):

Topical: Various topical calcium preparations have been used anecdotally for treatment of dermal exposure to HF solutions; Calcium Carbonate (Carcal) at concentrations ranging from 2.5% to 33% has been used; a topical Calcium Carbonate (Carcal) preparation must be compounded.

Renal Dose Adjustments

Patients with renal dysfunction have an increased risk of hypercalcemia. Periodically checking the serum calcium level, especially if signs or symptoms of hypercalcemia are detected, is recommended.

The use of Calcium Carbonate (Carcal) is not indicated for the treatment of hyperphosphatemia in patients with calculated or estimated creatinine clearance equal to or greater than 25 mL/min.

Liver Dose Adjustments

Data not available

Dialysis

Calcium is removed by hemodialysis. To ensure a positive net calcium flux into the patient during dialysis, a dialysate calcium concentration of 3 to 3.5 mEq/L is usually required. Mid-dialysis modest hypercalcemia is not uncommon when this concentration is used.

Calcium is removed by peritoneal dialysis. The standard peritoneal dialysate contains 3.5 mEq/L of calcium (in 1.5% dextrose) to maintain a positive calcium balance and to prevent calcium losses. When higher concentrations of dextrose are used, the net calcium balance may be negative because of a greater convective removal of calcium during ultrafiltration. This counterbalances the diffusion of calcium from the dialysate to the patient.

Other Comments

Dietary reference intake: Dosage is in terms of elemental calcium:

0 to 6 months: Adequate intake: 200 mg/day

7 to 12 months: Adequate intake: 260 mg/day

1 to 3 years: RDA: 700 mg/day

4 to 8 years: RDA: 1000 mg/day

9 to 18 years: RDA: 1300 mg/day

Adults, Female/Male: RDA:

19 to 50 years: 1000 mg/day

51 years and older, females: 1200 mg/day

51 to 70 years, males: 1000 mg/day

Female: Pregnancy/Lactating: RDA: Same as for Adults, Female/Male

Calcium Carbonate (Carcal):

Elemental calcium: 400 mg/1 g (20 mEq calcium/gram)

Approximate equivalent dose: 225 mg of calcium salt

Osteoporosis may be associated with increased serum parathyroid hormone, excessive alcohol intake, tobacco use, inactivity, and certain drugs. Additional factors to consider in males with osteoporosis include hypogonadism and/or age related decreases in serum testosterone. Adequate vitamin D intake and weight bearing exercise (if possible) are recommended.

Each 1 g of Calcium Carbonate (Carcal) contains 400 mg elemental calcium, or 20 mEq calcium.

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Calcium Carbonate (Carcal) interactions

See also:
What other drugs will affect Calcium Carbonate (Carcal)?

An interaction generally means that one drug may increase or decrease the effect of another drug. Also, the more medications a person takes, the more likely there will be a drug interaction. Antacids do interact with or prevent the absorption of many medications. As a general rule it is best to separate Calcium Carbonate (Carcal) use and any other medications by at least 1 hour. When antacids are only taken occasionally, this seldom presents a serious problem. Since there are so many good medications to reduce stomach acid, some of them over-the-counter, it is unusual to require frequent Calcium Carbonate (Carcal) use during the day and night.

Interactions with this Calcium Carbonate (Carcal) may occur with the following:

* flecainide (Tambocor)

* phenytoin type drugs (Dilantin, Mesantoin, Peganone, Cerebyx)

* iron (Feosol, ferrous sulfate, Nu-Iron)

* quinidine (Quinidex, Quinaglute)

* aspirin, salicylates

* tetracycline (Sumycin, Tetracyn)

Calcium Carbonate (Carcal) side effects

See also:
What are the possible side effects of Calcium Carbonate (Carcal)?

Applies to Calcium Carbonate (Carcal): tablets

Other dosage forms:

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation.

Seek medical attention right away if any of these SEVERE side effects occur while taking Calcium Carbonate (Carcal) (the active ingredient contained in Calcium Carbonate (Carcal))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; increased urination; loss of appetite; mental or mood changes; nausea; severe or persistent constipation or stomach pain; weakness; vomiting.

Calcium Carbonate (Carcal) contraindications

See also:
What is the most important information I should know about Calcium Carbonate (Carcal)?

Known hypersensitivity reaction to any of the ingredients of Calcium Carbonate (Carcal).

Active ingredient matches for Carcal:

Calcitriol/Calcium Carbonate in India.

Calcitriol

Calcium Carbonate


Unit description / dosage (Manufacturer)Price, USD
10's
Carcal Calcitriol 0.25 mg, Calciumcarbonate 500 mg. SG-CAP / 10
CARCAL soft-gelatin cap 10's (Santiago)$ 1.67
Carcal Calcitriol 0.25 mg, Calciumcarbonate 500 mg. SG-CAP / 10

List of Carcal substitutes (brand and generic names):

Cartiglu 500+250 Tablet (Prompt Cure Pharma Pvt Ltd)$ 0.08
Cartiglu 750+1.5 Tablet (Prompt Cure Pharma Pvt Ltd)$ 0.10
Cartigrow Tablet (Kim Laboratories Pvt Ltd.)$ 0.06
Cartiwin 500 mg+250 mg+50 iu Tablet (Faith Pharmaceuticals Ltd)$ 0.16
Cartiwin Collagen peptide 93 g, omega-3fatty acids 1 g, vitamin D3550 IU/100 g. POWD / 150g (Faith Pharmaceuticals Ltd)$ 4.75
Cason D 500 mg+7.5 mg+0.25 mcg Tablet (Esma Formulations)$ 0.14
Cason-D Calcium carbonate 500 mg, Alfacalcidol 0.25 mcg, Elemental zinc 7.5 mg. TAB / 10 (Esma)$ 1.43
10's (Esma)$ 1.43
CASON-D tab 10's (Esma)$ 1.43
Cav M Tablet (Ravian Life Sciences (P) Ltd)$ 0.01
CC2 Forte 500 mg+7.5 mg+0.25 mcg Capsule (Unilite Medicare Pvt Ltd)$ 0.15
Ccz Plus Calcitriol 0.25 mcg, Calciumcitrate maleate 1250 mg, Zinc7.5 mg. TAB / 100 (CureMax (Solitaire Pharmacia Pvt Ltd))$ 11.90
100's (CureMax (Solitaire Pharmacia Pvt Ltd))$ 11.90
Ccz Plus 1250 mg+7.5 mg+0.25 mcg Tablet (CureMax (Solitaire Pharmacia Pvt Ltd))$ 0.12
CCZ PLUS tab 10's (CureMax (Solitaire Pharmacia Pvt Ltd))$ 1.19
Cecal Calcium carbonate 1.25 g, Vitamin D3 250 IU, L-lysinemonohydrochloride 100 mg, Zincsulphate 35 mg, Magnesium 30mg. TAB / 10 (Care Pharmaceuticals)$ 0.40
10's (Care Pharmaceuticals)$ 0.40
Cecal 500 mg+50 mg+250 iu Tablet (Care Pharmaceuticals)$ 0.03
CECAL tab 10's (Care Pharmaceuticals)$ 0.40
Cedok 500 mg+0.25 mcg Tablet (Organic Labs Pvt. Ltd.)$ 0.08
Ceedee 500 mg+250 iu Tablet (Alcare Laboratories Pvt Ltd)$ 0.04
Cekal Forte Calcitriol 25 mcg, calciumcarbonate 500 mg, zinc 7.5 mg. S-GEL / 10x10 (Auriga Labs)$ 14.29
Cekal Forte 500 mg+7.5 mg+25 mcg Capsule (Auriga Labs)$ 0.14
CEKAL FORTE soft-gelatin cap 10's (Auriga Labs)$ 1.43
Celol INJ 1mcg x 1mL AMP / 1 (Emcure (Shweiz))$ 1.21
1 mcg x 1 mL x 1's (Emcure (Shweiz))$ 1.21
CELOL INJ inj 1 mcg x 1 mL x 1ml (Emcure (Shweiz))$ 1.21
Celol-XT Elemental calcium 500 mg, calcitriol 0.25 mcg, soyisoflavones 60 mg. CAP / 10 (Emcure)$ 2.05
CELOL-XT cap 10's (Emcure)$ 2.05
Cepacin 500 mg+7.5 mg+0.25 mcg Capsule (B B Remedies (P) Ltd)$ 0.09
Cepacin 200 ml Syrup (B B Remedies (P) Ltd)$ 0.02
Cepaflex Capsule (B B Remedies (P) Ltd)$ 0.09
Cezcal 200 ml Suspension (Ceza Formulations Pvt.Ltd)$ 0.02
Cezcal-D3 1250 mg+250 iu Tablet (Ceza Formulations Pvt.Ltd)$ 0.03
Chalkcap 350 mg x 100 x 10's (Charoon Bhesaj)

References

  1. DailyMed. "CALCIUM CARBONATE; FAMOTIDINE; MAGNESIUM HYDROXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CALCIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DailyMed. "CALCITRIOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Carcal are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Carcal. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Carcal before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Carcal. To get the time effectiveness of using Carcal drug by other patients, please click here.
Users%
> 3 month1
100.0%


1 consumer reported age

Users%
> 601
100.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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