Cetirizine/Phenylpropanolamine Uses

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Cetirizine/Phenylpropanolamine indications

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Relief of nasal and non-nasal symptoms associated with seasonal or perennial allergic rhinitis.

Cetirizine/Phenylpropanolamine dosage

Adult & child >12 yrs: 1 tab tid.

Cetirizine/Phenylpropanolamine interactions

Antihypertensive agents that interfere with sympathetic activity (eg, mecamylamine, methyldopa, reserpine)

Antihypertensive effects of these agents may be reduced.

Digitalis

Increased ectopic pacemaker activity.

MAOIs (eg, phenelzine)

Coadministration is contraindicated with pseudoephedrine and for 14 days after stopping the MAOI.

Sympathomimetic amines

Additive or potentiated effects on the CV system.

Laboratory Test Interactions

Positive reactions to skin tests may be prevented or diminished.

Cetirizine/Phenylpropanolamine side effects

CNS

Insomnia (4%); fatigue, somnolence (2%); dizziness (1%).

EENT

Pharyngitis (2%); epistaxis (1%).

GI

Dry mouth (4%).

Respiratory

Sinusitis (1%).

Miscellaneous

Accidental injury (1%).

Cetirizine/Phenylpropanolamine contraindications

Narrow-angle glaucoma; urinary retention; severe hypertension; severe coronary artery disease; patients receiving MAOIs or within 14 days of stopping such treatment; hypersensitivity to any component of the product, adrenergic agents, or other drugs of similar chemical structure; manifestations of patient idiosyncrasy to adrenergic agents, including arrhythmias, dizziness, insomnia, tremor, or weakness.


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Active ingredient matches for Cetirizine/Phenylpropanolamine:

Cetirizine/Phenylpropanolamine


List of Cetirizine/Phenylpropanolamine substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
ALERID-D tab 10's (Cipla)$ 0.36
Capsule; Oral; Cetirizine Hydrochloride 5 mg; Phenylpropanolamine Hydrochloride 120 mg
Capsules; Oral; Cetirizine Hydrochloride 5 mg; Phenylpropanolamine Hydrochloride 120 mg

References

  1. DailyMed. "CETIRIZINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "cetirizine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "cetirizine". http://www.drugbank.ca/drugs/DB00341 (accessed September 17, 2018).

Reviews

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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