Consists of chlophedianol, triprolidine
What is Chlophedianol (Chlophedianol and triprolidine)?
Chlophedianol (Chlophedianol and triprolidine) is used to relieve dry, irritating coughs. Chlophedianol (Chlophedianol and triprolidine) should not be used when there is mucus or phlegm (pronounced flem) with the cough.
Chlophedianol (Chlophedianol and triprolidine) relieves cough by acting on the cough center in the brain.
Chlophedianol (Chlophedianol and triprolidine) is available without a doctor's prescription.
Chlophedianol (Chlophedianol and triprolidine) description
Chlophedianol (Chlophedianol and triprolidine) is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
What are the possible side effects of Chlophedianol (Chlophedianol and triprolidine)?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Rare
- Hallucinations (seeing, hearing, or feeling things that are not there)
- nightmares
- skin rash or hives
- unusual excitement or irritability
- Blurred vision
- drowsiness or dizziness
- dryness of the mouth
- nausea or vomiting
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Copyright 2016 Truven Health Analytics, Inc. All Rights Reserved.
What is Triprolidine (Chlophedianol and triprolidine)?
Triprolidine (Chlophedianol and triprolidine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Triprolidine (Chlophedianol and triprolidine) is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.
Triprolidine (Chlophedianol and triprolidine) may also be used for purposes not listed in this medication guide.
Triprolidine (Chlophedianol and triprolidine) indications
Triprolidine (Chlophedianol and triprolidine) is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of pseudoephedrine and Triprolidine (Chlophedianol and triprolidine) is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.
How should I use Triprolidine (Chlophedianol and triprolidine)?
Use Triprolidine (Chlophedianol and triprolidine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Triprolidine (Chlophedianol and triprolidine) may be taken with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Use Triprolidine (Chlophedianol and triprolidine) exactly as directed on the package, unless instructed differently by your doctor. If you are taking Triprolidine (Chlophedianol and triprolidine) without a prescription, follow any warnings and precautions on the label.
- If you miss a dose of Triprolidine (Chlophedianol and triprolidine) and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Triprolidine (Chlophedianol and triprolidine).
Uses of Triprolidine (Chlophedianol and triprolidine) in details
Triprolidine (Chlophedianol and triprolidine) is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing.
This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. By blocking another natural substance made by your body (acetylcholine), it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose.
Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.
These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).
How to use Triprolidine (Chlophedianol and triprolidine)
Take this medication by mouth with or without food as directed by your doctor, usually every 6 hours. Do not take more than 4 doses in a 24-hour period. Follow all directions on the product package. This medication may be taken with food or milk if stomach upset occurs.
Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed. Do not take more of this medication than recommended for your age. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
If your symptoms do not improve after 7 days, if they worsen, if you develop fever/chills, or if you think you may have a serious medical problem, get medical help right away.
Triprolidine (Chlophedianol and triprolidine) description
First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness. [PubChem]
Triprolidine (Chlophedianol and triprolidine) dosage
Triprolidine (Chlophedianol and triprolidine) Dosage
Generic name: Triprolidine (Chlophedianol and triprolidine) Hydrochloride 1.25mg in 5mL
Dosage form: oral liquid
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Adults
2 Teaspoonfuls every 4 to 6 hours not to exceed 4 doses in a 24 hour period.
Children 6 to 12
1 Teaspoonful every 4 to 6 hours not to exceed 4 doses in a 24 hour period.
This product is not indicated for use in children under 6 years of age.
More about Triprolidine (Chlophedianol and triprolidine) (Triprolidine (Chlophedianol and triprolidine))
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Consumer resources
- Other brands: Zymine, Triprolidine (Chlophedianol and triprolidine), Zymine XR, Histex Syrup, More (1) »
Professional resources
- Triprolidine (Chlophedianol and triprolidine) (FDA)
- Triprolidine (Chlophedianol and triprolidine) Hydrochloride (AHFS Monograph)
Other formulations
- Triprolidine (Chlophedianol and triprolidine) D
Related treatment guides
- Allergic Rhinitis
- Allergic Urticaria
- Allergies
- Conjunctivitis, Allergic
- Eye Redness/Itching
- More (1) »
Triprolidine (Chlophedianol and triprolidine) interactions
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What other drugs will affect Triprolidine (Chlophedianol and triprolidine)?
Triprolidine (Chlophedianol and triprolidine) may enhance the sedative effects of central nervous system depressants including alcohol, barbiturates, hypnotics, narcotic analgesics, sedatives, and tranquillisers. The effects of anticholinergic drugs, such as atropine and tricyclic antidepressants may be enhanced by the concomitant administration of Triprolidine (Chlophedianol and triprolidine). Triprolidine (Chlophedianol and triprolidine) may effect the metabolism of drugs in the liver.
Triprolidine (Chlophedianol and triprolidine) side effects
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What are the possible side effects of Triprolidine (Chlophedianol and triprolidine)?
Drowsiness, dizziness, headache, nausea, vomiting, loss of appetite, constipation, stomach upset, blurred vision, decreased coordination, and dry mouth/nose/throat may occur. These effects may decrease as your body adjusts to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. Triprolidine (Chlophedianol and triprolidine) can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as hallucinations, irritability, nervousness), ringing in the ears, trouble urinating, easy bruising/bleeding, fast/irregular heartbeat, seizures.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Triprolidine (Chlophedianol and triprolidine) contraindications
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.
Ask a doctor or pharmacist if it is safe for you to take pseudoephedrine and Triprolidine (Chlophedianol and triprolidine) if you have:
kidney disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
an enlarged prostate; or
problems with urination.
Active ingredient matches for Chlophedianol and triprolidine:
List of Chlophedianol and triprolidine substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| chlophedianol/triprolidine | |
| Triprolidine/ chlophedianol liquid | |
| Triprolidine/Chlophedianol | |
| Triprolidine/Chlophedianol Liquid | |
References
- PubChem. "triprolidine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "triprolidine". http://www.drugbank.ca/drugs/DB00427 (accessed September 17, 2018).
- MeSH. "Histamine H1 Antagonists". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Chlophedianol and triprolidine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Chlophedianol and triprolidine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
