Chlordiazepoxide Uses

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What is Chlordiazepoxide?

Chlordiazepoxide is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Chlordiazepoxide affects chemicals in the brain that may become unbalanced and cause anxiety.

Chlordiazepoxide is used to treat anxiety disorders or alcohol withdrawal.

Chlordiazepoxide may also be used for other purposes not listed in this medication guide.

Chlordiazepoxide indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Chlordiazepoxide Capsule is indicated for the management of anxiety disorders or for the short term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

The effectiveness of Chlordiazepoxide Capsule in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.

How should I use Chlordiazepoxide?

Use Chlordiazepoxide injection as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Chlordiazepoxide injection.

Uses of Chlordiazepoxide in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Chlordiazepoxide is used to treat anxiety and acute alcohol withdrawal. It is also used to relieve fear and anxiety before surgery. This medication belongs to a class of drugs called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA).

How to use Chlordiazepoxide

Take this medication by mouth as directed by your doctor. The dosage is based on your age, medical condition, and response to treatment.

Use this medication exactly as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. Also, if used for an extended period of time, do not suddenly stop using this drug without your doctor's approval. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased to avoid side effects such as seizures.

When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.

Chlordiazepoxide description


A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Chlordiazepoxide has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia but has largely been superseded by the benzodiazepines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Chlordiazepoxide is a controlled substance in the U.S.

Chlordiazepoxide dosage

Chlordiazepoxide Dosage

Applies to the following strength(s): 5 mg; 10 mg; 25 mg; 100 mg

The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Anxiety

Mild to moderate anxiety: 5 or 10 mg orally, 3 or 4 times per day

Severe anxiety: 20 or 25 mg orally, 3 or 4 times per day

Use: Relief of mild, moderate, and severe anxiety disorders

Usual Adult Dose for Light Sedation

On days preceding surgery, 5 to 10 mg orally, 3 or 4 times per day

Use: Relief of preoperative apprehension and anxiety

Usual Adult Dose for Alcohol Withdrawal

50 to 100 mg orally, followed by repeated doses as needed until agitation is controlled

Maximum dose: 300 mg orally per day

Use: Relief of withdrawal symptoms of acute alcoholism

Usual Geriatric Dose for Anxiety

Elderly or debilitated patients:

5 mg orally, 2 to 4 times per day

Use: Relief of mild, moderate, and severe anxiety disorders

Usual Pediatric Dose for Anxiety

6 years or older:

5 mg orally, 2 to 4 times per day; this may be increased to 10 mg orally, 2 to 3 times per day

Use: Relief of mild, moderate, and severe anxiety disorders

Renal Dose Adjustments

Renal impairment: Use with caution

Liver Dose Adjustments

Hepatic impairment: Use with caution


Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV


Data not available

Other Comments

Storage requirements:

-Protect from light


-Psychiatric: Patients with a history of alcohol or drug abuse, or patients with a marked personality disorder should be monitored frequently.

Patient advice:

-Patients should be cautioned against performing activities requiring complete mental alertness, such as operating machinery or driving a motor vehicle.

More about Chlordiazepoxide

Consumer resources

Professional resources

Related treatment guides

Chlordiazepoxide interactions

See also:
What other drugs will affect Chlordiazepoxide?


When this drug applied simultaneously with:

- antipsychotic drugs (neuroleptics), antidepressants, sedatives, hypnotics, anesthetics, analgesics, ethanol enhanced the inhibitory effect on central nervous system, especially when administered parenterally.

- concomitant use of antacids can delay but not reduce the absorption of Chlordiazepoxide.

- hormonal contraceptives increases the effectiveness of Chlordiazepoxide.

- with muscle relaxants may enhance the action of muscle relaxants, with levodopa - may suppress antiparkinsonian action.

- theophylline at low doses perverts sedative effect of Chlordiazepoxide.

- phenobarbital and phenytoin may accelerate the metabolism of Chlordiazepoxide. In rare cases this medication inhibits the metabolism and enhances the action of phenytoin.

- may increase the toxicity of cyclophosphamide.

- cimetidine, omeprazole, disulfiram may increase the intensity and duration of action of this medicine.

Chlordiazepoxide side effects

See also:
What are the possible side effects of Chlordiazepoxide?

Applies to Chlordiazepoxide: oral capsule, oral tablet

As well as its needed effects, Chlordiazepoxide (the active ingredient contained in Chlordiazepoxide) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking Chlordiazepoxide, check with your doctor immediately:


Incidence not known:

If any of the following symptoms of overdose occur while taking Chlordiazepoxide, get emergency help immediately:

Symptoms of overdose:

Minor Side Effects

Some Chlordiazepoxide side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

Chlordiazepoxide contraindications

See also:
What is the most important information I should know about Chlordiazepoxide?

this medicine is contraindicated in the presence of glaucoma (since the anticholinergic component may produce some degree of mydriasis) and in patients with prostatic hypertrophy and benign bladder neck obstruction. It is contraindicated in patients with known hypersensitivity to Chlordiazepoxide and/or clidinium bromide.

Active ingredient matches for Chlordiazepoxide:


Unit description / dosage (Manufacturer)Price, USD
Capsule; Oral; Chlordiazepoxide Hydrochloride 10 mg
Capsule; Oral; Chlordiazepoxide Hydrochloride 25 mg
Capsule; Oral; Chlordiazepoxide Hydrochloride 5 mg
Librax 2.5-5 mg capsule$ 6.50
Librax capsule$ 5.78
Librium 25 mg capsule$ 2.14
Limbitrol DS 10-25 mg tablet$ 1.93
Librium 10 mg capsule$ 1.61
Librium 5 mg capsule$ 0.84
Chlordiazepoxide 25 mg capsule$ 0.72
ChlordiazePOXIDE HCl 25 mg capsule$ 0.32
ChlordiazePOXIDE HCl 10 mg capsule$ 0.31
ChlordiazePOXIDE HCl 5 mg capsule$ 0.31
Chlordiazepoxide 5 mg capsule$ 0.20
Apo-Chlordiazepoxide 25 mg Capsule$ 0.17
Chlordiazepoxide 10 mg capsule$ 0.14
Apo-Chlordiazepoxide 10 mg Capsule$ 0.11
Apo-Chlordiazepoxide 5 mg Capsule$ 0.07
Chlordiazepoxide / Pfoshen 10 mg x 1000's
Capsules; Oral; Chlordiazepoxide Hydrochloride 10 mg
Capsules; Oral; Chlordiazepoxide Hydrochloride 25 mg
Capsules; Oral; Chlordiazepoxide Hydrochloride 5 mg
Chlordiazepoxide 5 mg Tablet$ 0.00
Chlordiazepoxide capsule 5 mg (Aa Pharma Inc (Canada))
Chlordiazepoxide capsule 10 mg (Aa Pharma Inc (Canada))
Chlordiazepoxide capsule 25 mg (Aa Pharma Inc (Canada))
Chlordiazepoxide capsule 25 mg/1 (DIRECT RX (US))

List of Chlordiazepoxide substitutes (brand and generic names):

100 capsule in 1 bottle
500 capsule in 1 bottle
Chlordiazepoxide Hydrochloride capsule 25 mg/1 (REMEDYREPACK INC. (US))
Chlordiazepoxide Hydrochloride capsule, gelatin coated 5 mg/1 (Av Kare, Inc. (US))
Chlordiazepoxide Hydrochloride capsule 10 mg/1 (Mylan Institutional Inc. (US))
Chlordiazepoxide Hydrochloride capsule 5 mg/1 (Physicians Total Care, Inc. (US))
Chlordiazepoxide Hydrochloride capsule, gelatin coated 10 mg/1 (Av Kare, Inc. (US))
Chlordiazepoxide Hydrochloride capsule, gelatin coated 25 mg/1 (Av Kare, Inc. (US))
Chlordiazepoxide March Pharma 25 mg x 1's
Capsule; Oral; Chlordiazepoxide Hydrochloride 10 mg
Capsule; Oral; Chlordiazepoxide Hydrochloride 25 mg
Capsules; Oral; Chlordiazepoxide Hydrochloride 10 mg
Capsules; Oral; Chlordiazepoxide Hydrochloride 25 mg
Chlordixide 5 mg x 1's
Chlordixide 10 mg x 1's
Chlozep 10+1 Tablet (Synokem Pharmaceuticals Ltd)$ 0.04
CHLOZEP 1MG/10MG TABLET 1 strip / 10 tablets each (Synokem Pharmaceuticals Ltd)$ 0.52
Chlozep 1 mg/10 mg Tablet (Synokem Pharmaceuticals Ltd)$ 0.05
CLIDOX Capsule/ Tablet / 5mg - 2.5mg / 100 units (Moraceae Pharmaceuticals (P) Ltd.)$ 2.38
Clidox Clidinium Br. 2.5mg, Chlordiazepoxide 5mg TAB / 100 (Moraceae Pharmaceuticals (P) Ltd.)$ 2.76
100's (Moraceae Pharmaceuticals (P) Ltd.)$ 5.56
Clidox Clidinium bromide 2.5 mg, Chlordiazepoxide 5 mg, Dicyclomine hydrochloride 10mg. TAB / 100 (Moraceae Pharmaceuticals (P) Ltd.)$ 5.56
Clidox 10+5+2.5 Tablet (Moraceae Pharmaceuticals (P) Ltd.)$ 0.06
CLIDOX 2.5 MG/5 MG/10 MG TABLET 1 strip / 10 tablets each (Moraceae Pharmaceuticals (P) Ltd.)$ 0.53


  1. DailyMed. "AMITRIPTYLINE HYDROCHLORIDE; CHLORDIAZEPOXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed September 17, 2018).
  2. PubChem. "chlordiazepoxide". (accessed September 17, 2018).
  3. DrugBank. "chlordiazepoxide". (accessed September 17, 2018).


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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