Chlorpheniramine Maleate Uses

Rating: 1.65 - 3 review(s)
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Chlorpheniramine Maleate indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Infectious-inflammatory diseases caused by microorganisms susceptible to ciprofloxacin, including respiratory diseases, diseases of abdominal and pelvic organs, bones, joints, skin, septicemia; severe infections of ENT organs. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.

For Chlorpheniramine Maleate Citadel Fine Pharmaceuticals local use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meybomity. Infectious lesions in the eyes from injury or contact with foreign bodies. Preoperative prophylaxis in ophthalmic surgery.

Chlorpheniramine Maleate description

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. [PubChem]

Chlorpheniramine Maleate dosage

Individual. For oral administration dose of Chlorpheniramine Maleate Citadel Fine Pharmaceuticals is 250-750 mg 2 times / day. Treatment duration is from 7-10 days to 4 weeks.

For IV administration a single dose is 200-400 mg, the multiplicity of the introduction is 2 times / day, duration of treatment - 1-2 weeks and more if necessary. May be IV injected as jet but more preferably a drip for 30 minutes.

When Chlorpheniramine Maleate Citadel Fine Pharmaceuticals applied topically instilled 1-2 drops into the lower conjunctival sac of the affected eye every 1-4 hours. After improving the intervals between instillation can be increased. The maximum oral daily dose for adults is 1.5 g.

Chlorpheniramine Maleate interactions

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Activity increases when combined with beta-lactam antibiotics, aminoglycosides, vancomycin, clindamycin, metronidazole. Sukralfat, bismuth preparations, antacids containing aluminum ions, magnesium or calcium, cimetidine, ranitidine, vitamin and mineral supplement, iron sulfate, zinc, didanosine (recommended for 2 hours before or 4 hours after these drugs) reduce the suction. Probenecid, azlocillin increase the concentration in the blood. Decreases clearance and increases in plasma caffeine, aminophylline and theophylline (increased likelihood of side effects). Chlorpheniramine Maleate Citadel Fine Pharmaceuticals enhances the effect of warfarin and other oral anticoagulants (prolongs bleeding time). Increases nephrotoxicity of cyclosporine, increase the risk of CNS excitability and convulsive reactions against the background of NSAIDs. Medicines alkalinizing the urine (citrates, sodium bicarbonate, carbonic anhydrase inhibitors) reduce the solubility (increases the probability of crystalluria). Infusion solutions of ciprofloxacin ready to use can be combined with infusion solutions: 0.9% sodium chloride solution, Ringer's solution, Ringer lactate, 5 and 10% dextrose, 10% solution of fructose, and a solution containing 5% dextrose with 0,225 or 0.45% sodium chloride. Incompatible with solutions having a pH > 7.

Chlorpheniramine Maleate side effects

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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Fever

skin rash or itching

sore throat and fever

unusual tiredness and weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abdominal or stomach pain or upset

diarrhea

nausea or vomiting

Rare

Dizziness

hair loss

headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Chlorpheniramine Maleate contraindications

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Injection: Chlorpheniramine Maleate is contraindicated in comatose states, in patients who have received large amounts of central-nervous-system depressants (alcohol, sedative hypnotics, including barbiturates, general anesthetics, narcotics, narcotic analgesics, tranquilizers, etc.), and in patients who have demonstrated an idiosyncrasy or hypersensitivity to promethazine.

Under no circumstances should promethazine be given by intra-arterial injection due to the likelihood of severe arteriospasm and the possibility of resultant gangrene

Chlorpheniramine Maleate HCl injection should not be given by the subcutaneous route; evidence of chemical irritation has been noted, and necrotic lesions have resulted on rare occasions following subcutaneous injection. The preferred parenteral route of administration is by deep intramuscular injection.

Syrup, Tablets and Suppositories: Phenergan Tablets and Suppositories are contraindicated for use in pediatric patients less than two years of age.

Phenergan Tablets and Suppositories are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines.

Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma.



Active ingredient matches for Chlorpheniramine Maleate:

Chlorphenamine in Oman, Taiwan, United States.

Dexchlorpheniramine in United States.


Unit description / dosage (Manufacturer)Price, USD
Chlorpheniramine Maleate / VPP 4 mg x 1000's
Chlorpheniramine Maleate / Washington 4 mg x 1000's
Chlorpheniramine Maleate / Johnson 4 mg x 1000's
Chlorpheniramine Maleate / Johnson 8 mg x 1000's
Chlorpheniramine Maleate / S.T. 5 mg/1 mL x 1 mL
Chlorpheniramine Maleate / K.S. 4 mg x 1000's
Chlorpheniramine Maleate / Honten 4 mg x 1000's
Chlorpheniramine Maleate / Jen Sheng 4 mg x 1000's
Chlorpheniramine Maleate / Unifarma 4 mg
Chlorpheniramine Maleate / Prince 4 mg x 1000's
Chlorpheniramine Maleate / Sinton 5 mg/1 mL x 1 mL
Chlorpheniramine Maleate 10 mg Injection$ 0.05
Chlorpheniramine Maleate 4 mg Bini Tablet$ 0.00
Chlorpheniramine Maleate 4 mg Low Cost Tablet$ 0.05
Chlorpheniramine Maleate 4 mg Tablet$ 0.00
Chlorpheniramine Maleate 300 mg Injection$ 0.01
Chlorpheniramine Maleate tablet 4 mg/1 (Contract Pharmacy Services Pa (US))
Chlorpheniramine Maleate tablet, film coated, extended release 12 mg/1 (Kvk Tech, Inc. (US))

List of Chlorpheniramine Maleate substitutes (brand and generic names):

Chlorpheno 2 mg/5 mL x 60 mL (Milano)
Chlorpheno 2 mg/5 mL x 1 gal (Milano)
Chlorpheno 10 mg/1 mL x 1 mL x 50's (Milano)
Chlorpyrimine 4 mg x 1000's (Atlantic Lab)
Chlorpyrimine 10 mg/1 mL x 10 mL x 1's (Atlantic Lab)
Chlorpyrimine 4 mg x 1, 000's (Atlantic Lab)
Chlorpyrimine 10 mg/1 mL x 1 mL x 50's (Atlantic Lab)
Chlorpyrimine tab 4 mg 1000's (Atlantic Lab)
Chorphen 4 mg x 1, 000's
CLOMIN Capsule/ Tablet / 20mg - 500mg / 1000 units (Core Healthcare Ltd.)$ 5.12
CLOMIN Capsule/ Tablet / 20mg - 500mg / 10 units (Core Healthcare Ltd.)$ 0.11
CLOMIN Drops / 10mg per ml / 10ml units (Core Healthcare Ltd.)$ 0.13
CLOMIN Injection / 20mg / 2ml units (Core Healthcare Ltd.)$ 0.03
Clomin 20+500 Tablet (Core Healthcare Ltd.)$ 0.01
CLOMIN 20MG/500MG DROPS 1 packet / 10 ML drop each (Core Healthcare Ltd.)$ 0.36
CLOMIN 20MG/500MG TABLET 1 packet / 1000 tablets each (Core Healthcare Ltd.)$ 7.53
CLOMIN DROPS 1 packet / 15 ML drop each (Core Healthcare Ltd.)$ 0.26
Clomin 20 mg/500 mg Drop (Core Healthcare Ltd.)$ 0.36
Clomin Drop (Core Healthcare Ltd.)$ 0.26
Clopheniramin DOMESCO 4 mg x 5 Blister x 20 Tablet
Clopheniramin DOMESCO 4 mg x 20 Blister x 10 Tablet
Clopheniramin DOMESCO 4 mg x 1 Bottle 200 Tablet
Clopheniramin DOMESCO 4 mg x 1 Bottle 500 Tablet

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "DEXCHLORPHENIRAMINE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "chlorpheniramine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Chlorpheniramine Maleate are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Chlorpheniramine Maleate. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Chlorpheniramine Maleate drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Not useful1
100.0%


Consumer reported price estimates

No survey data has been collected yet


Consumer reported time for results

No survey data has been collected yet


3 consumers reported age

Users%
30-452
66.7%
1-51
33.3%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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