Clearest Dosage

Rating: 5 - 3 review(s)
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How times a day do you take this medicine?

Dosage of Clearest in details

The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Do not break or chew tablet; swallow tablet whole

Adults and Children 12 Years and over:

take 1 tablet every 12 hours; do not take more than 2 tablets in 24 hours

Adults 65 years and over:

Ask a doctor

Children under 12 years of age:

Ask a doctor

Consumers with liver or kidney disease:

Ask a doctor

Clearest (Cetirizine (Clearest), Pseudoephedrine (Clearest)) Tablets may be given with or without food.

How supplied

Clearest (Cetirizine (Clearest), Pseudoephedrine (Clearest)) Tablets are white, round, biconvex, bilayer tablets containing 5 mg Cetirizine (Clearest) hydrochloride in an immediate release layer and 120 mg Pseudoephedrine (Clearest) hydrochloride in an extended release layer. Clearest (Cetirizine (Clearest), Pseudoephedrine (Clearest)) Tablets are supplied in high-density polyethylene bottles of 100 tablets fitted with polypropylene child-resistant closures (NDC 0069-1630-66).

Clearest (Cetirizine (Clearest), Pseudoephedrine (Clearest)) Tablets are engraved with Clearest (Cetirizine (Clearest), Pseudoephedrine (Clearest)) on one side.

STORAGE: Store at 20°C to 25°C (68° to 77°F)

For questions contact McNEIL-PPC, Inc at 1.800.343.7805

What other drugs will affect Clearest?

Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Cetirizine (Clearest).

Before taking this medication, tell your doctor if you are also using any of the following drugs:

  • digoxin (digitalis, Lanoxin);
  • blood pressure medication, especially methyldopa (Aldomet), mecamylamine (Inversine), or reserpine; or
  • diet pills, stimulants, or ADHD medications.

This list is not complete and there may be other drugs that can interact with Cetirizine (Clearest) and Pseudoephedrine (Clearest). Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Clearest interactions

Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Clearest, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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No interaction studies have been performed with the combination Cetirizine (Clearest)-Pseudoephedrine (Clearest).

Lack of Interactions: Pharmacokinetic interaction studies were conducted with Cetirizine (Clearest) and cimetidine, ketoconazole, erythromycin, azithromycin, antipyrine and Pseudoephedrine (Clearest); no pharmacokinetic interactions were observed.

Studies with Cetirizine (Clearest) and cimetidine, glipizide, diazepam, and Pseudoephedrine (Clearest) have revealed no evidence of adverse pharmacodynamic interactions.

Studies with Cetirizine (Clearest) and azithromycin, erythromycin, ketoconazole, theophylline and Pseudoephedrine (Clearest) have revealed no evidence of adverse clinical interactions. In particular, concomitant administration of Cetirizine (Clearest) with macrolides or ketoconazole has never resulted in clinically relevant ECG changes.

Sedatives: No clinically significant interaction has been described with Cetirizine (Clearest), but caution is recommended on concomitant use of sedatives.

Theophylline: In a multiple-dose study of theophylline (400 mg once a day) and Cetirizine (Clearest), there was a small (16%) decrease in clearance of Cetirizine (Clearest), while the disposition of theophylline was not altered by concomitant Cetirizine (Clearest) administration.

Ritonavir: In a multiple-dose study of ritonavir (600 mg twice daily) and Cetirizine (Clearest) (10 mg daily), the extent of exposure to Cetirizine (Clearest) was increased by about 40% while the disposition of ritonavir was not altered by concomitant Cetirizine (Clearest) administration.

Monoamine Oxidase Inhibitors (MAOIs): Concomitant use of sympathomimetic amines with MAOIs can result in hypertensive crisis. Because of the long duration of action of MAOIs, this interaction is still possible 15 days after stopping such a treatment.

Dihydroergotamine and Linezolid: An increase in blood pressure can also occur on concomitant administration of dihydroergotamine or linezolid.

Risk of Vasoconstriction and Increased Blood Pressure: The following combinations are not recommended as there is a risk of vasoconstriction and increased blood pressure: Bromocriptine, pergolide, lisuride, cabergoline, as well as dihydroergotamine, ergotamine, methylergometrine, and other vasoconstrictors used as oral or nasal decongestants (phenylpropanolamine, phenylephrine, ephedrine, etc).

Reduction of the Antihypertensive Effects of Drugs: Sympathomimetic amines may reduce the antihypertensive effects of β-adrenergic blockers and of drugs that interfere with sympathetic activity eg, methyldopa, guanethidine and reserpine.

Tricyclic Antidepressants (TCAs): Tricyclic antidepressants can potentiate the hypertensive effect of Pseudoephedrine (Clearest).

Digitalis: The ectopic activity of a pacemaker can be increased when Pseudoephedrine (Clearest) is used with digitalis; use of Clearest is therefore not advised in digitalised patients.

Drugs Increasing or Decreasing Clearest Absorption: Antacids and proton pump inhibitors increase the rate of Pseudoephedrine (Clearest) absorption; kaolin decreases it.

Ventricular Arrhythmia: Concurrent use with halogenated anaesthetic agents eg, chloroform, enflurane, isoflurane, cyclopropane, halothane may provoke or worsen ventricular arrhythmia.

Tests for Allergies: Antihistamines can interfere with cutaneous tests for allergies and an appropriate wash-out period is required before conducting such tests.

Fat Meal: A high-fat meal was not found to modify the bioavailability of both active ingredients, but it resulted however in a reduced and delayed peak plasma concentration of Cetirizine (Clearest).

Incompatibilities: There are no relevant data available.


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References

  1. DailyMed. "PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CETIRIZINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. FDA/SPL Indexing Data. "7CUC9DDI9F: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Clearest are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Clearest. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

4 consumers reported frequency of use

How frequently do I need to take Clearest?
It was reported by ndrugs.com website users that Clearest should ideally be taken Once in a day as the most common frequency of the Clearest. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Clearest should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
Users%
Once in a day2
50.0%
4 times in a day1
25.0%
Twice in a day1
25.0%


3 consumers reported doses

What doses of Clearest drug you have used?
The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Clearest drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users%
6-10mg2
66.7%
501mg-1g1
33.3%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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