Clinoxid Uses

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What is Clinoxid?

Clindamycin is an antibiotic. Clinoxid prevents bacteria from growing on the skin.

Clinoxid (for the skin) is used to treat severe acne in adults and children who are at least 12 years old.

Clinoxid may also be used for other purposes not listed in this medication guide.

Clinoxid indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Clinoxid 2%, is indicated in the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis). Clinoxid 2%, can be used to treat non-pregnant women and pregnant women during the second and third trimester.

NOTE: For purposes of this indication, a clinical diagnosis of bacterial vaginosis is usually defined by the presence of a homogeneous vaginal discharge that (a) has a pH of greater than 4.5, (b) emits a “fishy” amine odor when mixed with a 10% KOH solution, and (c) contains clue cells on microscopic examination. Gram's stain results consistent with a diagnosis of bacterial vaginosis include (a) markedly reduced or absent Lactobacillus morphology, (b) predominance of Gardnerella morphotype, and (c) absent or few white blood cells.

Other pathogens commonly associated with vulvovaginitis, eg, Trichomonas vaginalis, Chlamydia trachomatis, N. gonorrhoeae, Candida albicans, and Herpes simplex virus should be ruled out.

How should I use Clinoxid?

Use Clinoxid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Clinoxid.

Uses of Clinoxid in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Clinoxid is used to treat severe acne (acne vulgaris) and vaginal infections caused by certain bacteria.

Clinoxid description

An antibacterial agent that is a semisynthetic analog of lincomycin.

Clinoxid dosage

Apply a thin film of Clinoxid

Topical Solution, Clinoxid

Topical Lotion, Clinoxid

Topical Gel, or use a Clinoxid

Topical Solution pledget for the application of Clinoxid twice daily to affected area. More than one pledget may be used. Each pledget should be used only once and then be discarded.

Lotion: Shake well immediately before using.

Pledget: Remove pledget from foil just before use. Do not use if the seal is broken. Discard after single use.

Keep all liquid dosage forms in containers tightly closed.

How supplied

Clinoxid

Topical Solution

containing clindamycin phosphate equivalent to 10 mg clindamycin per milliliter is available in the following sizes:

30 mL applicator bottle - NDC 0009-3116-01

60 mL applicator bottle - NDC 0009-3116-02

Carton of 60 single-use pledget applicators - NDC 0009-3116-14

Clinoxid

Topical Gel

containing clindamycin phosphate equivalent to 10 mg clindamycin per gram is available in the following sizes:

60 gram tube - NDC 0009-3331-01

30 gram tube - NDC 0009-3331-02

Clinoxid

Topical Lotion

containing clindamycin phosphate equivalent to 10 mg clindamycin per milliliter is available in the following size:

60 mL plastic squeeze bottle - NDC 0009-3329-01

Store at controlled room temperature 20° to 25°C (68° to 77°F).

Protect from freezing.

Distributed by: Pharmacia & Upjohn Company, Division of Pfizer Inc., NY, NY 10017. Revised April 2014

Clinoxid interactions

See also:
What other drugs will affect Clinoxid?

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Clinoxid Lotion has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.

Clinoxid side effects

See also:
What are the possible side effects of Clinoxid?

Applies to Clinoxid: vaginal cream, vaginal suppository

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by Clinoxid (the active ingredient contained in Clinoxid). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Clinoxid, check with your doctor or nurse as soon as possible:

More common:

Less common: Rare

Side Effects: Post Treatment

After you stop taking this drug, it is possible that you may still experience side effects that need medical attention. If you notice any of the following side effects check with your doctor immediately:

Clinoxid contraindications

See also:
What is the most important information I should know about Clinoxid?

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Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Clinoxid and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid getting this medication in your eyes. If it does get into your eyes, rinse thoroughly with water.

It may take up several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve or if they get worse.

Although the risk of serious side effects is low when clindamycin is applied to the skin, side effects can occur if the medication is absorbed into your bloodstream.

Before using this medication, tell your doctor if you have an intestinal disorder such as ulcerative colitis, if you have ever had eczema, or if you have ever had severe diarrhea caused by antibiotic medicine.

Active ingredient matches for Clinoxid:

Clindamycin topical

Benzoyl peroxide/clindamycin in India.


Unit description / dosage (Manufacturer)Price, USD
CLINOXID 1% GEL 1 tube / 15 GM gel each (Ajanta Pharma Ltd)$ 5.16
CLINOXID 2.5% CREAM 1 tube / 15 GM cream each (Ajanta Pharma Ltd)$ 3.94
CLINOXID topical gel 15g (Ajanta)$ 5.16

List of Clinoxid substitutes (brand and generic names):

Clinred-B Clindamycin phosphate 1 %, benzoyl peroxide 5 %. CRM / 15g (Encore)$ 3.16
CLINRED-B cream 15g (Encore)$ 3.16
Clinrik 1% w/w Gel (Mascot Health Series Pvt Ltd)$ 1.44
Clinrik N Gel (Mascot Health Series Pvt Ltd)$ 1.54
CLINXA CREAM 1 tube / 20 GM cream each (Canixa Life Sciences Pvt)$ 1.67
CLINZIT 1% GEL 1 tube / 10 GM gel each (Jainik)$ 0.71
CLINZIT topical gel 1 % x 20g (Jainik)
CLIVE GEL 1 tube / 10 GM gel each (Alive Pharmaceutical Pvt Ltd)$ 0.79
D ACNE 1% W/W GEL 1 tube / 10 GM gel each (Glenmark Pharmaceuticals Ltd)$ 1.71
D ACNE FACE WASH 1 tube / 60 ML face wash each (Glenmark Pharmaceuticals Ltd)$ 5.56
D ACNE SOAP 1 packet / 75 GM soap each (Glenmark Pharmaceuticals Ltd)$ 2.22
DERLIN GEL 1 tube / 10 GM gel each (Alliance Healthcare P Ltd)$ 0.81
Gel; Topical; Benzoyl Peroxide, Hydrous 5%; Clindamycin Phosphate 1% (Stiefel)
Duac Once Daily 6 g (Stiefel)
Duac Once Daily 25 g (Stiefel)
Duac Once Daily topical gel 5 g x 1's (Stiefel)
Duac Once Daily topical gel 25 g x 1's (Stiefel)
ECNACARE 1% GEL 1 tube / 20 GM gel each (Omega Remedies Pvt Ltd)$ 1.06
ECNACARE 1% OINTMENT 1 tube / 10 GM ointment each (Omega Remedies Pvt Ltd)$ 0.85
Ecnacare 1% Ointment (Omega Remedies Pvt Ltd)$ 0.09
EFATOP LOTION 1 bottle / 100 ML lotion each (Adcock Ingram Healthcare Pvt Ltd)$ 1.71
Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Gabriel)
KLINSPEC 1% CREAM 1 tube / 15 GM cream each (Novartis India Ltd)$ 0.89
MAGNATHROCIN 2% CREAM 1 tube / 15 GM cream each (Magnachem Pharmaceuticals Pvt Ltd)$ 0.97
MAGNATHROCIN 4% CREAM 1 tube / 15 GM cream each (Magnachem Pharmaceuticals Pvt Ltd)$ 0.97
Magnathrocin 4% Cream (Magnachem Pharmaceuticals Pvt Ltd)$ 0.97
OXIMIN cap 10's (Tulip)
5 % x 30g (Affy)$ 0.87
Perclin 5% CRM / 30g (Affy)$ 0.87

References

  1. DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "BENZOYL PEROXIDE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "clindamycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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