Clinoxid Pregnancy

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Pregnancy of Clinoxid in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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This drug should be used during pregnancy only if clearly needed. AU TGA pregnancy category: A US FDA pregnancy category: B

Animal studies have failed to reveal evidence of fetal harm when given oral or parenteral doses up to 300 mg/kg/day. Approximately 1.1% of pregnant patients in their second trimester given the vaginal cream experienced abnormal labor, compared to 0.5% of patients given placebo. There are no controlled data in the first trimester of human pregnancy. AU TGA pregnancy category A: Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

See references

Clinoxid breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

This drug is excreted into breastmilk when given orally or intravenously.

Use is not recommended and a decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown Excreted into animal milk: Unknown Comment: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Cleocin vaginal cream (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
  2. "Product Information. Cleocin T (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
  3. "Product Information. Clindesse (Clinoxid)." Ther-Rx Corporation, Bridgeton, MO.
  4. Cerner Multum, Inc. "Australian Product Information." O 0
  5. "Product Information. Evoclin (Clinoxid)." Connetics Inc, Palo Alto, CA.
  6. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  7. "Product Information. Cleocin Vaginal Ovules (Clinoxid)" Pharmacia and Upjohn, Kalamazoo, MI.

References for breastfeeding information

  1. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
  2. "Product Information. Evoclin (Clinoxid)." Connetics Inc, Palo Alto, CA.
  3. "Product Information. Cleocin Vaginal Ovules (Clinoxid)" Pharmacia and Upjohn, Kalamazoo, MI.
  4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  5. Cerner Multum, Inc. "Australian Product Information." O 0
  6. "Product Information. Clindesse (Clinoxid)." Ther-Rx Corporation, Bridgeton, MO.
  7. "Product Information. Cleocin vaginal cream (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
  8. "Product Information. Cleocin T (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.


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References

  1. DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubMed Health. "Clindamycin (Into the vagina) (Cleocin Vaginal): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  3. PubMed Health. "Benzoyl Peroxide (On the skin): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).

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