To avoid and correct vitamin deficiency, which may
result from an imbalanced or special diet, impaired
absorption, anorexia, slimming, pathological intestinal
flora, debilitating disease or therapy with drugs acting
as vitamin antagonists.
Clinvan syrup meets the increased vitamin requirements
during periods of intensive growth, and as a dietary
supplement in premature and newborn infants.
Clinvan is used to treat vitamin B3 deficiency and inflammatory skin diseases like acne and pellagra.
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]
Treatment and prophylaxis of nicotinic acid deficiency
Adult: Up to 500 mg daily in divided doses. May also be given via IM or by slow IV inj.
Mild to moderate inflammatory acne
Adult: As a 4% gel: Apply bid, reduce to once daily or on alternate days if irritation occurs.
Clinvan: The clearance of primidone and carbamazepine may be reduced with the concomitant use of Clinvan.
Zinc Oxide: The absorption of quinolones or tetracycline may be decreased with the concomitant use of zinc.
Cupric Oxide: Concomitant use of penicillamine and copper can cause decreased absorption of both substances.
Allergic sensitization has been reported rarely following oral and parenteral administration of Folic Acid.
At recommended doses, Clinvan is expected to be well tolerated. Gastrointestinal distress such as nausea or vomiting have been associated with the administration of Clinvan or zinc at doses greater than the recommended dose of Clinvan
Clinvan: Dizziness, headache, hyperglycemia, nausea, vomiting, diarrhea, elevations in liver function tests, hepatotoxicity, blurred vision, flushing, rash.
contraindicated in patients with hypersensitivity to any of its components.
|Unit description / dosage (Manufacturer)||Price, USD|
|Clinvan Skin 15 gm Gel||$ 1.08|
List of Clinvan substitutes (brand and generic names):
|CLINKA-N GEL 1 tube / 10 GM gel each (Intas Pharmaceuticals Ltd.)||$ 1.21|
|Corix Skin 15 gm Cream (Lanark Laboratories Pvt Ltd)||$ 0.94|
|Florabic Paed Tablet|
|Florabic Paed Tablet (Micro Organics Pharmaceuticals (India) Pvt.Ltd)||$ 0.03|
|Freederm (United Kingdom)|
|Gel; Topical; Vitamin B3 / Nicotinamide 4% (Dendron)|
|5g (Dendron)||$ 0.32|
|Freederm Treatment (United Kingdom)|
|Freederm Treatment 4% (United Kingdom)|
|Fulzyme MPS Tablet|
|Fulzyme MPS Tablet (Eden Healthcare)||$ 0.02|
|Funin 1 g|
|Gevital Capsule (Alice Healthcare (P) Ltd)||$ 0.10|
|Glory Forte Skin 30 gm Cream (Multicure (Laborate Pharmaceuticals India Ltd.))||$ 0.76|
|Grabvit Plus Inj Injection (Hecure Healthcare Pvt Ltd)||$ 0.56|
|Gzlacne Skin 15 gm Cream (Gedzrlvin Pharmaceuticals)||$ 1.14|
|Hercobal Plus Inj Injection (Servocare Lifesciences)||$ 0.78|
|Intabion Tab Tablet|
|Intabion Tab Tablet (Intas Laboratories Pvt Ltd)||$ 0.02|
|J P Tone|
|J P Tone Inj Injection (Jagsonpal Pharmaceuticals Ltd)||$ 0.38|
|J P Tone 200 ml Syrup (Jagsonpal Pharmaceuticals Ltd)||$ 0.07|
|Klinmide Skin 15 gm Gel (Mefro Dermacare)||$ 0.71|
|N Cobal OD|
|N Cobal OD Inj Injection (Antigen Healthcare P. Ltd.)||$ 0.86|
|Nervic Inj Injection (Unimarck Pharma (India) Limited)||$ 0.25|
|Nervic 200 ml Syrup (Unimarck Pharma (India) Limited)||$ 0.03|
|Nervic 1500 mcg Tablet (Unimarck Pharma (India) Limited)||$ 0.10|
|NERVIC INJECTION 1 vial / 2 ML injection each (Unimarck Pharma (India) Limited)||$ 0.29|
|NERVIC tab 1.5 mg x 10's (Unimarck Pharma (India) Limited)||$ 0.87|
|Nerviphar 1000 mcg+100 mg+10 mg Injection (Altruist Pharmacia Pvt Ltd)||$ 0.77|
|Neuro Power Inj Injection (Atlantic Pharmaceuticals)||$ 0.35|
|Neuromind Plus Inj Injection (Allminds Labs (P) Ltd)||$ 0.31|
|Niacef 4 % x 15 g x 1's (Cipan)||$ 2.67|
|Niacex Isdin (Chile)|
|Niacex-S Isdin (Chile)|
|NIACIN NF 1000 MG TABLET 1 strip / 10 tablets each (Nouveau Medicament Pvt Ltd)||$ 1.10|
|Niacinamida Pharma Arte (Paraguay)|
|Nicam (Ireland, United Kingdom)|
|Gel; Topical; Vitamin B3 / Nicotinamide 4% (Dermal laboratories)|
|Nicam 4% (United Kingdom)|
|Nicobion (France, Germany)|
|Tablet; Oral; Vitamin B3 / Nicotinamide (Astrazeneca)|
|Nicoclin Skin 10 gm Gel (La Med India)||$ 0.89|
|> 3 month||2||100.0%|
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Information checked by Dr. Sachin Kumar, MD Pharmacology