Clobetasol Uses

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What is Clobetasol?

Clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. The solution are used for scalp problems, the foam is used for mild to moderate plaque psoriasis, the cream, lotion, and spray are used for moderate to severe plaque psoriasis, and the foam and shampoo are used for moderate to severe scalp psoriasis. Clobetasol is a corticosteroid (cortisone-like medicine or steroid).

Clobetasol is available only with your doctor's prescription.

Clobetasol indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Indication

Clobetasol lotion, 0.05% is a super-high potent topical corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses only in patients 18 years of age or older. Treatment should be limited to 2 consecutive weeks. For moderate to severe plaque psoriasis, treatment may be extended for an additional 2 weeks for localized lesions (less than 10% body surface area) that have not sufficiently improved after the initial 2-week treatment. Any additional benefits of extending treatment should be weighed against the risk of hypothalamic-pituitary-adrenal (HPA) axis suppression before prescribing for more than 2 weeks. The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz) per week.

Patients should be instructed to use Clobetasol lotion, 0.05% for the minimum amount of time necessary to achieve the desired results.

Use in patients under 18 years of age is not recommended due to numerically high rates of HPA axis suppression.

Limitations of Use

Clobetasol lotion, 0.05% should not be used on the face, axillae, or groin and should not be used if there is atrophy at the treatment site. Clobetasol lotion, 0.05% should not be used in the treatment of rosacea or perioral dermatitis.

How should I use Clobetasol?

Use Clobetasol foam as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Clobetasol foam.

Uses of Clobetasol in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Clobetasol is used to treat itching, redness, dryness, swelling, and discomfort of various scalp and skin conditions, including immune-mediated skin disease with red scaly patches (psoriasis).

Clobetasol description

A derivative of prednisolone with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than fluocinonide, it is used topically in treatment of psoriasis but may cause marked adrenocortical suppression. [PubChem]

Clobetasol dosage

Clobetasol (Clobetasol scalp application) Application should be applied to the affected scalp areas twice daily, once in the morning and once at night.

Clobetasol (Clobetasol scalp application) Application is potent; therefore, treatment must be limited to 2 consecutive weeks and amounts greater than 50 mL/week should not be used.

Clobetasol (Clobetasol scalp application) Application is not to be used with occlusive dressings.

Geriatric Use: In studies where geriatric patients {65 years of age or older, see PRECAUTIONS) have been treated with Clobetasol (Clobetasol scalp application) Application, safety did not differ from that in younger patients; therefore, no dosage adjustment is recommended.

How supplied

Clobetasol (Clobetasol scalp application) Application, 0.05% is supplied in plastic squeeze bottles, 25 mL {NDC 0173-0432-00) and 50 mL (NDC 0173-0432-01). Store between 4° and 25°C (39° and 77°F). Do not use near an open flame.

Glaxo Wellcome Inc. Research Triangle Park, NC 27709. August 2000. FDA rev date: 4/2/2003

Clobetasol interactions

See also:
What other drugs will affect Clobetasol?

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* If you are taking this product under your doctor’s direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.

* Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. If prescribed by your doctor, tell your doctor or pharmacist of all prescription or nonprescription/herbal products you may use before using this product.

Clobetasol side effects

See also:
What are the possible side effects of Clobetasol?

In a controlled clinical trial with Clobetasol gel, the only reported adverse reaction that was considered to be drug related was a report of burning sensation (1.8% of treated patients). In controlled clinical trials, the most frequent adverse reactions reported for Clobetasol cream were burning and stinging sensation in 1% of treated patients. Less frequent adverse reactions were itching, skin atrophy, and cracking and fissuring of the skin. In controlled clinical trials, the most frequent adverse events reported for Clobetasol ointment were burning sensation, irritation, and itching in 0.5% of treated patients. Less frequent adverse reactions were stinging, cracking, erythema, folliculitis, numbness of fingers, skin atrophy, and telangiectasia.

Cushing's syndrome has been reported in infants and adults as a result of prolonged use of topical Clobetasol formulations. The following additional local adverse reactions have been reported with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids. These reactions are listed in an approximately decreasing order of occurrence: dryness, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, irritation, striae, and miliaria.

Clobetasol contraindications

See also:
What is the most important information I should know about Clobetasol?

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Clobetasol (Clobetasol scalp application) Application is contraindicated in patients with primary infections of the scalp, or in patients who are hypersensitive to Clobetasol, other corticosteroids, or any ingredient in this preparation.

Active ingredient matches for Clobetasol:

Clobetasol Propionate in Antigua & Barbuda, Aruba, Austria, Bahamas, Bahrain, Bangladesh, Barbados, Belgium, Bermuda, Bosnia & Herzegowina, Bulgaria, Canada, Cayman Islands, Chile, China, Colombia, Czech Republic, Estonia, Ethiopia, Georgia, Grenada, Guyana, Hong Kong, Hungary, Indonesia, Ireland, Israel, Jamaica, Japan, Latvia, Lithuania, Malaysia, Malta, Netherlands, Oman, Peru, Philippines, Poland, Romania, Russian Federation, Saint Lucia, Singapore, South Africa, South Korea, Switzerland, Taiwan, Thailand, Trinidad & Tobago, Turkey, United Kingdom, Venezuela, Vietnam.

Clobetasol in Romania.


Unit description / dosage (Manufacturer)Price, USD
Cream; Topical; Clobetasol Propionate 0.05%
Ointment; Topical; Clobetasol Propionate 0.05%
Solution; Topical; Clobetasol Propionate 0.05%
Lotion; Topical; Clobetasol Propionate 0.05%
Gel; Topical; Clobetasol Propionate 0.05%
Cream; Topical; Clobetasol 0.05%
Ointment; Topical; Clobetasol 0.05%
Aerosol, Foam; Topical; Clobetasol Propionate 0.05%
Clobex 0.05% Lotion 118ml Bottle$ 513.56
Clobex Spray 0.05% Liquid 125ml Bottle$ 501.70
Olux 0.05% Foam 100 gm Can$ 443.77
Olux-E 0.05% Foam 100 gm Can$ 384.32
Olux Olux-E Complete Pack 0.05 & 0.05% Miscellaneous 110 gm Can$ 373.65
Clobex 0.05% Shampoo 118ml Bottle$ 365.67
Clobetasol Propionate 0.05% Foam 100 gm Can$ 326.37
Clobex 0.05% Lotion 59ml Bottle$ 280.80
Clobex Spray 0.05% Liquid 59ml Bottle$ 278.93
Olux 0.05% Foam 50 gm Can$ 239.07
Temovate 0.05% Cream 60 gm Tube$ 234.19
Temovate 0.05% Gel 60 gm Tube$ 234.19
Temovate E 0.05% Cream 60 gm Tube$ 234.19
Clobetasol Propionate 0.05% Foam 50 gm Can$ 177.05
Temovate 0.05% Ointment 30 gm Tube$ 132.55
Temovate 0.05% Solution 50ml Bottle$ 113.82
Temovate 0.05% Cream 45 gm Tube$ 95.43
Clobetasol Propionate 0.05% Gel 60 gm Tube$ 93.82
Temovate 0.05% Ointment 15 gm Tube$ 82.10
Clobetasol 17-prop powder$ 70.74
Clobetasol Propionate 0.05% Cream 60 gm Tube$ 64.15
Clobetasol Propionate 0.05% Ointment 60 gm Tube$ 64.15
Clobetasol Propionate 0.05% Gel 30 gm Tube$ 51.66
Clobetasol Propionate 0.05% Ointment 45 gm Tube$ 50.56
Clobetasol Propionate 0.05% Cream 45 gm Tube$ 48.57
Temovate 0.05% Gel 15 gm Tube$ 47.38
Temovate E 0.05% Cream 15 gm Tube$ 44.90
Clobetasol Propionate 0.05% Solution 50ml Bottle$ 41.18
Clobetasol Propionate 0.05% Cream 30 gm Tube$ 34.79
Clobetasol Propionate 0.05% Ointment 30 gm Tube$ 34.79
Clobetasol Propionate 0.05% Gel 15 gm Tube$ 28.86
Clobetasol Propionate 0.05% Solution 25ml Bottle$ 26.99
Clobetasol Propionate 0.05% Cream 15 gm Tube$ 24.94
Clobetasol Propionate 0.05% Ointment 15 gm Tube$ 24.10
Olux 0.05% foam$ 6.77
Olux-e 0.05% foam$ 5.90
Clobex 0.05% topical lotion$ 4.58
Temovate emollient 0.05% crm$ 3.75
Olux-olux-e complete pack$ 3.43
Temovate 0.05% cream$ 3.29
Cormax 0.05% cream$ 2.06
Embeline 0.05% cream$ 1.86
Clobetasol 0.05% cream$ 1.43
Dermovate 0.05 % Cream$ 0.72
Dermovate 0.05 % Ointment$ 0.72
Dermovate 0.05 % Lotion$ 0.63
Mylan-Clobetasol 0.05 % Cream$ 0.38
Mylan-Clobetasol 0.05 % Ointment$ 0.38
Novo-Clobetasol 0.05 % Cream$ 0.38
Novo-Clobetasol 0.05 % Ointment$ 0.38
Pms-Clobetasol 0.05 % Cream$ 0.38
Pms-Clobetasol 0.05 % Ointment$ 0.38
Ratio-Clobetasol 0.05 % Cream$ 0.38
Ratio-Clobetasol 0.05 % Ointment$ 0.38
Taro-Clobetasol 0.05 % Cream$ 0.38
Taro-Clobetasol 0.05 % Ointment$ 0.38
Mylan-Clobetasol 0.05 % Lotion$ 0.33
Pms-Clobetasol 0.05 % Lotion$ 0.33
Ratio-Clobetasol 0.05 % Lotion$ 0.33
Taro-Clobetasol 0.05 % Lotion$ 0.33
Clobetasol 0.5 mg/1 g x 1 g
Clobetasol 0.5 mg/1 g x 5 g
Clobetasol 0.5 mg/1 g x 7 g
Clobetasol 0.5 mg/1 g x 10 g
Clobetasol 0.5 mg/1 g x 450 g
Shampoo; Topical; Clobetasol Propionate 0.05%

List of Clobetasol substitutes (brand and generic names):

CLOBETAMIL cream 0.05 % w/w x 10g (Merck (India) Ltd (Merck Ltd))$ 0.45
Cream; Topical; Clobetasol Propionate 0.05%
15 gram in 1 tube
30 gram in 1 tube
45 gram in 1 tube
Clobetasol Propionate aerosol, foam .5 mg/g (Prasco Laboratories (US))
Clobetasol Propionate lotion .5 mg/mL (Paddock Laboratories, LLC (US))
Clobetasol Propionate spray .05 g/mL (Actavis Pharma, Inc. (US))
Clobetasol Propionate shampoo .05 g/100mL (Sandoz Inc. (US))
Clobetasol Propionate ointment .5 mg/g (Golden State Medical Supply, Inc. (US))
Clobetasol Propionate solution .5 mg/mL (Novel Laboratories, Inc. (US))
Clobetasol Propionate cream .5 mg/g (Hi Tech Pharmacal Co., Inc. (US))
Clobetasol Propionate gel .5 mg/g (Taro Pharmaceuticals U.S.A., Inc. (US))

References

  1. DailyMed. "CLOBETASOL PROPIONATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "clobetasol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "CLOBETASOL PROPIONATE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Clobetasol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Clobetasol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

3 consumers reported useful

Was the Clobetasol drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful3
100.0%


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Clobetasol drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
100.0%


1 consumer reported time for results

To what extent do I have to use Clobetasol before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Clobetasol. To get the time effectiveness of using Clobetasol drug by other patients, please click here.
Users%
2 weeks1
100.0%


4 consumers reported age

Users%
46-602
50.0%
> 602
50.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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