Clobetasol BNM topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. The solution are used for scalp problems, the foam is used for mild to moderate plaque psoriasis, the cream, lotion, and spray are used for moderate to severe plaque psoriasis, and the foam and shampoo are used for moderate to severe scalp psoriasis. Clobetasol BNM is a corticosteroid (cortisone-like medicine or steroid).
Clobetasol BNM is available only with your doctor's prescription.
Clobetasol BNM indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Indication
Clobetasol BNM Propionate Spray, 0.05% is a super-high potent topical corticosteroid formulation indicated for the treatment of moderate to severe plaque psoriasis affecting up to 20% body surface area (BSA) in patients 18 years of age or older. The total dosage should not exceed 50 g (59 mL or 2 fl. oz.) per week. Do not use more than 26 sprays per application or 52 sprays per day. Treatment should be limited to 4 consecutive weeks. Patients should be instructed to use Clobetasol BNM Propionate Spray, 0.05% for the minimum amount of time necessary to achieve the desired results. Use in patients under 18 years of age is not recommended because safety has not been established and because numerically high rates of HPA axis suppression were seen with other Clobetasol BNM propionate topical formulations.
Limitations of Use
Clobetasol BNM Propionate Spray, 0.05% should not be used on the face, axillae, or groin. Clobetasol BNM Propionate Spray, 0.05% should not be used if there is atrophy at the treatment site. Clobetasol BNM Propionate Spray, 0.05% should not be used in the treatment of rosacea or perioral dermatitis.
How should I use Clobetasol BNM?
Use Clobetasol BNM emollient foam as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Wash your hands before using Clobetasol BNM emollient foam. If your fingers are warm, rinse them in cold water and dry before you apply Clobetasol BNM emollient foam.
Use the smallest amount of medicine necessary to cover the affected area.
Shake well before each use.
Turn the can upside down and squirt a small amount of foam (up to the size of a golf ball) into the cap of the can, onto a clean saucer, or onto another cool, clean surface. You may also squirt it directly onto the affected area. Do not squirt the medicine directly into the hand because it will start to melt immediately upon touching warm skin.
Gently rub the medicine into the affected area until it disappears.
Throw away any unused medicine that has been squirted out of the can.
Wash your hands immediately after using Clobetasol BNM emollient foam, unless your hands are a part of the treated area.
Do not use Clobetasol BNM emollient foam on your face, groin, or underarms unless your doctor tells you otherwise.
Do not use Clobetasol BNM emollient foam over large areas of the body without first checking with your doctor.
Do not bandage or wrap the affected area unless directed to do so by your doctor.
If you miss a dose of Clobetasol BNM emollient foam, apply it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Clobetasol BNM emollient foam.
Uses of Clobetasol BNM in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Clobetasol BNM is used to treat itching, redness, dryness, swelling, and discomfort of various scalp and skin conditions, including immune-mediated skin disease with red scaly patches (psoriasis).
Clobetasol BNM description
Clobetasol BNM is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Clobetasol BNM diminishes gastric acid and pepsin secretion. Clobetasol BNM also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
Clobetasol BNM dosage
Note: For proper dispensing of foam, hold the can upside down and depress the actuator.
Clobetasol BNM (Clobetasol BNM propionate) Foam should be applied to the affected area twice daily, once in the morning and once at night. Invert the can and dispense a small amount of Clobetasol BNM (Clobetasol BNM propionate) Foam (up to a maximum of a golf-ball-size dollop or one and a half capfuls) into the cap of the can, onto a saucer or other cool surface, or to the lesion, taking care to avoid contact with the eyes. Dispensing directly onto hands is not recommended (unless the hands are the affected area), as the foam will begin to melt immediately upon contact with warm skin. When applying Clobetasol BNM (Clobetasol BNM propionate) Foam to a hair-bearing area, move the hair away from the affected area so that the foam can be applied to each affected area. Pick up small amounts with fingertips and gently massage into affected area until the foam disappears. Repeat until entire affected area is treated.
Apply the smallest amount possible that sufficiently covers the affected area(s). No more than one and a half capfuls of foam should be used at each application. Do not apply to face or intertriginous areas.
Clobetasol BNM (Clobetasol BNM propionate) Foam is a super-high-potency topical corticosteroid; therefore, treatment should be limited to 2 consecutive weeks and amounts greater than 50 g/week should not be used. Use in pediatric patients under 12 years of age is not recommended. Unless directed by a physician, Clobetasol BNM (Clobetasol BNM propionate) Foam should not be used with occlusive dressings.
Instructions for applying Clobetasol BNM (Clobetasol BNM propionate) Foam
Apply Clobetasol BNM (Clobetasol BNM propionate) Foam twice a day, once in the morning and once at night. Apply only enough to cover the affected areas. Clobetasol BNM (Clobetasol BNM propionate) Foam should not be applied to the groin, armpits, or other skin fold areas.
To use Clobetasol BNM (Clobetasol BNM propionate) Foam:
Before applying Clobetasol BNM (Clobetasol BNM propionate) Foam for the first time, break the tiny plastic piece at the base of the can's rim by gently pushing back (away from the piece) on the nozzle.
Turn the can upside down.
Push the button to squirt a small amount of Clobetasol BNM (Clobetasol BNM propionate) Foam into the cap of the can, onto a saucer or other cool surface, or your affected skin area. This amount should be no more than 1 ½ capfuls, about the size of a golf ball.
Do not squirt Clobetasol BNM (Clobetasol BNM propionate) Foam directly onto your hands (unless your hands are the affected areas), because the foam will begin to melt right away on contact with your warm skin. If your fingers are warm, rinse them in cold water first. (Be sure to dry them thoroughly before handling the foam.)
If the can seems warm or the foam seems runny, run the can under cold water.
Using your fingertips, gently massage Clobetasol BNM (Clobetasol BNM propionate) Foam into the affected areas until the foam disappears.
If you are treating areas with hair such as the scalp, move any hair away so that the foam can be applied directly to the affected areas.
Repeat the process until the affected areas are treated.
Keep the foam away from your eyes, as it will sting and may cause eye problems if there is frequent contact with your eyes. If the foam gets in your eyes, rinse them well with cold water right away. If the stinging continues, contact your doctor right away.
Wash your hands after applying Clobetasol BNM (Clobetasol BNM propionate) Foam. Throw away any of the unused medicine that you squirted out of the can.
How supplied
Clobetasol BNM (Clobetasol BNM propionate) Foam is supplied in 100 g (NDC 63032-031-00) and 50 g (NDC 63032- 031-50) aluminum cans.
Store at controlled room temperature 68-77°F (20-25°C).
WARNING
FLAMMABLE. AVOID FIRE, FLAME OR SMOKING DURING AND IMMEDIATELY FOLLOWING APPLICATION. Keep out of reach of children. Contents under pressure. Do not puncture or incinerate container. Do not expose to heat or store at temperatures above 120°F (49°C).
Manufactured for : Connetics Corporation, Palo Alto, CA 94304, USA. For additional information: 1-888-500-DERM or visit, www.Clobetasol BNM (Clobetasol BNM propionate).com. VersaFoam-HF is a trademark, and the V logo, the interlocking C design, Clobetasol BNM (Clobetasol BNM propionate) and Connetics are registered trademarks, of Connetics Corporation. January 2006. FDA revision date: 7/11/2006
In a controlled pharmacokinetic study, 5 of 13 subjects experienced reversible suppression of the adrenals at any time during the 14 days of Clobetasol BNM (Clobetasol BNM propionate) Foam therapy to at least 20% of the body surface area. Of the 13 subjects studied, 1 of 9 with psoriasis were suppressed after 14 days and all 4 of the subjects with atopic dermatitis had abnormal cortisol levels indicative of adrenal suppression at some time after starting therapy with Clobetasol BNM (Clobetasol BNM propionate) Foam.
Table 3: Subjects with reversible HPA axis suppression at any time during treatment
Dermatosis
Clobetasol BNM Foam
Psoriasis
1 of 9
Atopic Dermatitis*
4 of 4
*Clobetasol BNM Foam is not indicated for non-scalp atopic dermatitis, as the safety and efficacy of Clobetasol BNM Foam in non-scalp atopic dermatitis has not been established. Use in children under 12 years of age is not recommended.
Systemic absorption of topical corticosteroids has produced reversible adrenal suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
In a controlled clinical trial (188 subjects) with Clobetasol BNM (Clobetasol BNM propionate) Foam in subjects with psoriasis of the scalp, there were no localized scalp adverse reactions reported in the Clobetasol BNM (Clobetasol BNM propionate) Foam treated subjects. In two controlled clinical trials (360 subjects) with Clobetasol BNM (Clobetasol BNM propionate) Foam in subjects with psoriasis of non-scalp regions, localized adverse events that occurred in the Clobetasol BNM (Clobetasol BNM propionate) Foam treated subjects included application site burning (10%), application site dryness ( < 1%), and other application site reactions (4%).
In larger controlled trials with other Clobetasol BNM propionate formulations, the most frequently reported local adverse reactions have included burning, stinging, irritation, pruritus, erythema, folliculitis, cracking and fissuring of the skin, numbness of the fingers, skin atrophy, and telangiectasia (all less than 2%).
The following additional local adverse reactions have been reported with topical corticosteroids, but they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids such as Clobetasol BNM (Clobetasol BNM propionate) Foam. These reactions are listed in an approximate decreasing order of occurrence: dryness, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, striae, and miliaria.
Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended.
Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.
Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with Clobetasol BNM topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.
Do not use this medication on a child without medical advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.
Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.
The results of a survey conducted on ndrugs.com for Clobetasol BNM are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Clobetasol BNM. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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