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Clocan Dosage |
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Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.
Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.
Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.
Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% Clocan cream to affected area two times daily for 7 consecutive days.
Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% Clocan cream to affected area two times daily for 7 consecutive days.
Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.
Regimen 4: One applicatorful of 1% Clocan vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.
Regimen 5: One applicatorful of 2% Clocan vaginal cream intravaginally once daily (preferably at bedtime) for 3 consecutive days.
Studies have shown the three and seven day courses of Clocan to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of Clocan.
Weekly or monthly Clocan vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.
> 3 years: Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.
> 3 years: Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.
> 3 years: Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.
> 3 years: Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
> 3 years: Apply Clocan topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
> 12 years: Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% Clocan cream to affected area two times daily for 7 consecutive days.
Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% Clocan cream to affected area two times daily for 7 consecutive days.
Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.
Regimen 4: One applicatorful of 1% Clocan vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.
Studies have shown the three and seven day courses of Clocan to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of Clocan.
Weekly or monthly Clocan vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.
Data not available
Data not available
Data not available
Since Clocan is not absorbed by your body, drug interactions are not expected. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines.
Clocan should be used cautiously in patients with hyperthyroidism, hypertension and cardiac arrhythmias. All vasopressors should be used cautiously in patients taking monoamine oxidase (MAO) inhibitors.
Clocan should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity.
Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other such drug has subsided.
Administration of epinephrine to patients receiving cyclopropane or halogenated hydrocarbon general anesthetics such as halothane which sensitize the myocardium, may induce cardiac arrhythmia.. When encountered, such arrhythmias may respond to administration of a beta-adrenergic blocking drug. Clocan also should be used cautiously with other drugs (e.g., digitalis, glycosides) that sensitize the myocardium to the actions of sympathomimetic drugs.
Diuretic agents may decrease vascular response to pressor drugs such as epinephrine.
Clocan may antagonize the neuron blockade produced by guanethidine resulting in decreased antihypertensive effect and requiring increased dosage of the latter.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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