Colese Uses

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Colese indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.

Uses of Colese in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Colese is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.

Colese description

Each capsule contains Mebeverine 200 mg.

Colese also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.

Colese dosage


Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).

Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.

Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.

Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).

It should not be chewed because the coating is intended to ensure a prolonged release mechanism.

Colese interactions

No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Colese and ethanol.

Incompatibilities: Not applicable.

Colese side effects


Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia and tachycardia have been reported in patients receiving Colese.

Colese contraindications

Hypersensitivity to Colese HCl or to any of the excipients of Colese.

Active ingredient matches for Colese:

Mebeverine in Australia, Taiwan.

Maprotiline in Taiwan.

Mebeverine Hcl

Mebeverine hydrochloride in Australia.

Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; Mebeverine Hydrochloride 135 mg
Colese 135 mg

List of Colese substitutes (brand and generic names):

Chum 135 mg x 1000's
Tablet; Oral; Mebeverine Hydrochloride 135 mg (Solvay)
Colofac Retard 200 mg x 30's (Solvay)
Colofac 135 mg x 50's (Solvay)
Capsule, Modified Release; Oral; Mebeverine Hydrochloride 200 mg
Colofac Retard PR cap 200 mg 30's (Abbott)
Colofac tab 135 mg 50's (Abbott)
Colonil 135 mg (Quesada)
Capsule; Oral; Mebeverine Hydrochloride 200 mg (Expanscience)
COLOSPA Capsule/ Tablet / 135mg / 10 units (Solvay Pharma India Pvt Ltd)$ 1.15
Colospa 135mg TAB / 10 (Solvay Pharma India Pvt Ltd)$ 1.24
135 mg x 10's (Solvay Pharma India Pvt Ltd)$ 1.24
Colospa 135 mg Tablet (Solvay Pharma India Pvt Ltd)$ 0.13
COLOSPA 135 MG TABLET 1 strip / 10 tablets each (Solvay Pharma India Pvt Ltd)$ 1.95
COLOSPA RETARD 200 MG TABLET 1 strip / 10 tablets each (Solvay Pharma India Pvt Ltd)$ 2.78
COLOSPA X TABLET 1 strip / 15 tablets each (Solvay Pharma India Pvt Ltd)$ 3.02
COLOSPA sugar-coated tab 135 mg x 10's (Solvay Pharma India Pvt Ltd)$ 1.48
Colospa 135mg Tablet (Solvay Pharma India Pvt Ltd)$ 0.21
Colospa 200mg Capsule (Solvay Pharma India Pvt Ltd)$ 0.31
Colospa X Tablet (Solvay Pharma India Pvt Ltd)$ 0.22
200 mg x 10's (Solvay Pharma India Pvt Ltd)$ 1.81
Colospa Retard 20mg CAP / 10 (Solvay Pharma India Pvt Ltd)$ 1.81
Colospa Retard 200 mg Capsule (Solvay Pharma India Pvt Ltd)$ 0.19
COLOSPA RETARD cap 200 mg x 10's (Solvay Pharma India Pvt Ltd)$ 2.10
Colospa Retard 20mg CAP / 10 (Solvay Pharma India Pvt Ltd)$ 1.81
Colospas FC tab 135 mg 30's (Nabiqasim)
Tablet; Oral; Mebeverine Hydrochloride 135 mcg (Agis)
135 mg x 10's (Cubit (Cucard))
Cuspa 135mg TAB / 10 (Cubit (Cucard))


  1. PubChem. "mebeverine". (accessed September 17, 2018).
  2. PubChem. "maprotiline". (accessed September 17, 2018).
  3. DrugBank. "Mebeverine". (accessed September 17, 2018).


The results of a survey conducted on for Colese are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Colese. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet

Consumer reported price estimates

No survey data has been collected yet

1 consumer reported time for results

To what extent do I have to use Colese before I begin to see changes in my health conditions?
As part of the reports released by website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Colese. To get the time effectiveness of using Colese drug by other patients, please click here.
1 day1

5 consumers reported age

> 603

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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