Colofac retard 200 mg Uses

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Colofac retard 200 mg indications

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Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.

Uses of Colofac retard 200 mg in details

Colofac retard 200 mg is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.

Colofac retard 200 mg description

Each capsule contains Mebeverine HCl 200 mg.

Colofac retard 200 mg also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.

Colofac retard 200 mg dosage

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Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).

Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.

Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.

Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).

It should not be chewed because the coating is intended to ensure a prolonged release mechanism.

Colofac retard 200 mg interactions

No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Colofac retard 200 mg and ethanol.

Incompatibilities: Not applicable.

Colofac retard 200 mg side effects

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Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia and tachycardia have been reported in patients receiving Colofac retard 200 mg.

Colofac retard 200 mg contraindications

Hypersensitivity to Colofac retard 200 mg HCl or to any of the excipients of Colofac retard 200 mg.

Active ingredient matches for Colofac retard 200 mg:

Mebeverine in Austria.


List of Colofac retard 200 mg substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Colonil 135 mg (Quesada)
Capsule; Oral; Mebeverine Hydrochloride 200 mg (Expanscience)
COLOSPA Capsule/ Tablet / 135mg / 10 units (Solvay Pharma India Pvt Ltd)$ 0.87
Colospa 135mg TAB / 10 (Solvay Pharma India Pvt Ltd)$ 0.94
135 mg x 10's (Solvay Pharma India Pvt Ltd)$ 0.94
Colospa 135 mg Tablet (Solvay Pharma India Pvt Ltd)$ 0.10
COLOSPA 135 MG TABLET 1 strip / 10 tablets each (Solvay Pharma India Pvt Ltd)$ 1.48
COLOSPA RETARD 200 MG TABLET 1 strip / 10 tablets each (Solvay Pharma India Pvt Ltd)$ 2.11
COLOSPA X TABLET 1 strip / 15 tablets each (Solvay Pharma India Pvt Ltd)$ 2.29
COLOSPA sugar-coated tab 135 mg x 10's (Solvay Pharma India Pvt Ltd)$ 1.12
Colospa 135mg Tablet (Solvay Pharma India Pvt Ltd)$ 0.16
Colospa 200mg Capsule (Solvay Pharma India Pvt Ltd)$ 0.23
Colospa X Tablet (Solvay Pharma India Pvt Ltd)$ 0.17
200 mg x 10's (Solvay Pharma India Pvt Ltd)$ 1.37
Colospa Retard 20mg CAP / 10 (Solvay Pharma India Pvt Ltd)$ 1.37
Colospa Retard 200 mg Capsule (Solvay Pharma India Pvt Ltd)$ 0.14
COLOSPA RETARD cap 200 mg x 10's (Solvay Pharma India Pvt Ltd)$ 1.59
Colospa Retard 20mg CAP / 10 (Solvay Pharma India Pvt Ltd)$ 1.37
Colospas FC tab 135 mg 30's (Nabiqasim)
Tablet; Oral; Mebeverine Hydrochloride 135 mcg (Agis)
DESPAS 10 MG/250 MG TABLET 1 strip / 10 tablets each (Dew Drops Lab)$ 0.30
Dobecon 100 mg x 10 x 10's
Dobecon 100 mg x 1000's
Tablet, Prolonged Release; Oral; Mebeverine Hydrochloride 200 mg (Saval)
Capsule; Oral; Mebeverine Hydrochloride 200 mg (Grunenthal)
Dragee; Oral; Mebeverine Hydrochloride 135 mg (Grunenthal)
Tablet, Film-Coated; Oral; Mebeverine Hydrochloride 100 mg (Grunenthal)
Capsule, Retard; Oral; Mebeverine Hydrochloride 200 mg

References

  1. PubChem. "mebeverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Mebeverine". http://www.drugbank.ca/drugs/DB12554 (accessed September 17, 2018).
  3. MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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