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Colofac/Colofac Retard Uses |
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Colofac/Colofac Retard is indicated for the symptomatic treatment
of irritable bowel syndrome and other conditions
usually included in this grouping, such as:
chronic irritable colon, mucous colitis, spastic colitis
and spastic constipation.
Colofac/Colofac Retard is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.
Each Colofac/Colofac Retard tablet also contains the following excipients: Tablet Core: Lactose monohydrate, starch (potato), povidone, talc, magnesium stearate. Tablet Coating: Talc, sucrose, gelatine, acacia, canuba wax.
Each Colofac/Colofac Retard Retard prolonged-release capsule also contains the following excipients: Magnesium stearate, copolymer of ethyl acrylate and methyl methacrylate, talc, methylhydroxypropylcellulose, methacrylic acid-ethyl acrylate copolymer (1:1) and glycerol.
Adult: Colofac/Colofac Retard: 1 tablet thrice daily, taken approximately 20 min before meals.
The physician will advice the patient on the duration of use of Colofac/Colofac Retard. Duration of use is not limited, however, after a period of several weeks when the desired effect has been obtained, the dosage may be gradually reduced.
Missed Dose: If ≥1 dose is missed, continue with the next dose as prescribed. Do not take the missed dose(s) in addition to the regular dose.
Colofac/Colofac Retard Retard: 1 capsule twice daily, to be given in the morning and evening.
Administration: The tablet/capsule should be swallowed with at least 100 mL (Colofac/Colofac Retard) water and should not be chewed because of the unpleasant taste.
Colofac/Colofac Retard: Tell the physician or pharmacist if taking or have recently taken any other medicines including medicines obtained without a prescription.
Interaction studies have only been performed with alcohol. In vitro and in vivo studies in animals have shown no significant interaction between Colofac/Colofac Retard and ethanol. No other interaction studies have been performed.
Incompatibilities: Not applicable.
In therapeutic doses, no adverse effects have
been reported. Rarely allergic reactions (including
rash, urticaria, angioedema), could be noticed.
USE DURING PREGNANCY AND LACTATION:
Animal experiments have failed to show any teratogenic
effects. However, administration of Colofac/Colofac Retard
is to be discouraged during pregnancy.
Colofac/Colofac Retard is not excreted in the milk of lactating
women after therapeutic doses.
For both cases, the medicine should be used with
physician advice.
No contraindications have been reported.
Colofac/Colofac Retard does not provoke any atropinic effect and for this reason is not contraindicated in patients with glaucoma or prostatic hypertrophy.
Mebeverine HCl in Thailand.
Unit description / dosage (Manufacturer) | Price, USD |
Colofac Retard PR cap 200 mg 30's (Abbott) | |
Colofac tab 135 mg 50's (Abbott) | |
List of Colofac/Colofac Retard substitutes (brand and generic names): | |
Anti-spa® | |
Despasm 135 | |
Duspacol 200 | |
Duspalina 135 | |
Duspaphen 135 | |
Dusparaz 135 | |
Dusparaz 200 | |
Duspatalin 杜適林 (Hongkong) | |
Mebagen | |
Mebetalin 135mg | |
Mebeverine HCl (Singapore) | |
Mevrin 135 (Myanmar) | |
Mevrin 135 tab 40's (S.J. & G. Fazul Ellahie) | |
Raverine 135 | |
Spasmocoline | |
Vermeb (Vietnam) | |
Vermeb 135 mg x 5 Blister x 10 Tablet |
Users | % | ||
---|---|---|---|
46-60 | 2 | 50.0% | |
30-45 | 1 | 25.0% | |
> 60 | 1 | 25.0% |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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