Conovate-N Uses

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Conovate-N indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Conovate-N preparations are indicated for the treatment of the following conditions where secondary bacterial infection is present, suspected, or likely to occur: eczema in adults and children (aged 2 years and over), including atopic and discoid eczemas; prurigo nodularis; psoriasis (excluding widespread plaque psoriasis); neurodermatoses including lichen simplex and lichen planus; seborrhoeic dermatitis; contact sensitivity reactions; insect bite reactions; and anal and genital intertrigo.

Conovate-N description

Each 100 g of cream contains Betamethasone (Conovate-N) valerate equivalent to Betamethasone (Conovate-N) 0.1 g and Neomycin (Conovate-N) sulfate equivalent to Neomycin (Conovate-N) 0.3 g.

Conovate-N dosage

Dosage: Adults and Adolescents: Usual Dose: Apply topically (to the skin) 1-3 times a day.

Children: Usual Dose: Apply topically (to the skin), once a day.

Administration:

Topical.

Conovate-N interactions

It is important to tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before using any new medicines while using this one, to ensure that the combination is safe.

If you are using any other types of eye, ear or nose drop you should administer them at least five minutes apart, to prevent the second drop washing away the first. Use gels or ointments last.

Conovate-N side effects

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Those Indicating Need for Medical Attention: Betamethasone (Conovate-N): Less Frequent or Rare Incidence: Allergic contact dermatitis (burning and itching of skin; apparent chronic therapeutic failure)- may also be caused by vehicle ingredients; folliculitis, furunculosis, pustules, pyoderma or vesiculation (painful, red or itchy, pus-containing blisters in hair follicles)- more frequent with occlusion or use of ointments in intertriginous areas; hyperesthesia (increased skin sensitivity); numbness in fingers; purpura (blood-containing blisters on skin); skin atrophy (thinning of skin with easy bruising, especially when used on facial or intertriginous area); skin infection, secondary- more frequent with occlusion; stripping of epidermal layer for tape dosage forms; telangiectasis (raises, dark red, wart-like spots on skin, especially when used on the face).

Rare Incidence: With prolonged use or other factors that increase absorption. Acneiform eruptions (acne or oily skin, especially when used on the face); cataracts, posterior subcapsular (gradual blurring or loss of vision)- reported with use of systemic corticosteroids; caution is advised with use of high- and very high-potency topical corticosteroids in periorbital area; cushing's syndrome (backache; filling or rounding out of the face; irritability; menstrual irregularities; mental depressions; in men, unusual decrease in sexual desire or ability; unusual tiredness or weakness); dermatitis, prioral (irritation of skin around mouth); ecchymosis (unusual bruising); edema (increased blood pressure; rapid weight; swelling of feet or lower legs); gastric ulcer (loss of appetite; nausea; stomach bloating, burning, cramping, or pain; vomiting; weight loss); glaucoma, secondary (eye pain; gradual decrease in vision; nausea; vomiting)- with use of high- and very high-potency topical corticosteroids in peritoneal area; hirsutism or hypertrichosis (unusual increase in hair growth, especially on the face); hypertension; hypokalemia syndrome (irregular heartbeat; loss of appetite; muscle cramps or pain; nausea; severe weakness of extremities and trunk; vomiting); hypopigmentation (lightened skin color); or other changes in skin pigmentation; aggravation of infection; miliaria rubra (burning and itching of skin with pinhead-sized red blisters); protein depletion (muscle weakness); skin laceration (tearing of skin); skin maceration (softening of skin); striae (reddish purple lines on arms, face, legs, trunk, or groin); SC tissue atrophy; unusual loss of hair especially on the scalp.

Neomycin (Conovate-N): More Frequent Incidence: Contact dermatitis (itching, rash, redness, swelling or other sign of skin irritation not present before therapy).

Rare Incidence: Ototoxicity (any loss of hearing).

Those Indicating Need for Medical Attention Only if They Continue or are Bothersome: Less Frequent or Rare Incidence: Burning, dryness, irritation, itching or redness of skin, mild and transient; increased redness or scaling of skin lesions, mild and transient; skin rash, minor and transient.

Those Not Indicating Need for Medical Attention Only if They Continue or are Bothersome: Stinging, mild and temporary, when foam, gel, lotion, solution or aerosol form of medication is applied.

Conovate-N contraindications

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•Rosacea.

•Acne vulgaris.

•Perioral dermatitis.

•Perianal and genital pruritus.

•Primary cutaneous viral infections (e.g. herpes simplex, chickenpox).

•Hypersensitivity to any component of the preparation.

•Use is not indicated in treatment of primary infected skin lesions caused by infection with fungi or bacteria; primary or secondary infections due to yeast; or secondary infections due to Pseudomonas or Proteus species.

•Dermatoses in children under 2 years of age, including dermatitis and napkin eruptions. A possibility of increased absorption exists in very young children, thus Conovate-N is not recommended for use in neonates and infants (up to 2 years). In neonates and infants, absorption by immature skin may be enhanced, and renal function may be immature.

•Preparations containing Neomycin (Conovate-N) should not be used for the treatment of otitis externa when the ear-drum is perforated, because of the risk of ototoxicity.

•Due to the known ototoxic and nephrotoxic potential of Neomycin (Conovate-N) sulphate, the use of Conovate-N in large quantities or on large areas for prolonged periods of time is not recommended in circumstances where significant systemic absorption may occur.



Active ingredient matches for Conovate-N:

Betamethasone/Neomycin in Thailand.

Betamethasone/Betamethasone valerate 01%/Neomycin/neomycin sulfate 05% in Thailand.


Unit description / dosage (Manufacturer)Price, USD
Conovate-N 5 g
Conovate-N 15 g
Conovate-N cream 15's (Community Pharm PCL)
Conovate-N cream 5's (Community Pharm PCL)

List of Conovate-N substitutes (brand and generic names):

Clinivate-N cream 450 g x 1's (Bangkok Lab & Cosmetic)
Cortiderm-N Betamethasone 0.05%w/w, Neomycin 0.5%w/w CRM / 15g (Bal Pharma)$ 0.44
15g (Bal Pharma)$ 0.44
CORTIDERM-N cream 15g (Bal Pharma)$ 0.44
Dermasole N 1 tube x 15 g
Dermasole N 1 Bottle 450 g
Derzid-N 5 g (Unison)
Derzid-N 15 g (Unison)
Derzid-N cream 15 g x 1's (Unison)
Derzid-N cream 5 g x 1's (Unison)
Diprovate-N Betamethasone Dipropionate0.05%w/w, Neomycin Sulphate0.5%w/w CRM / 16g (Fulford)$ 0.44
16g (Fulford)$ 0.44
Diprovate-N Betamethasone dipropionate0.05 %, neomycin sulphate 0.5%. CRM / 16g (Fulford)$ 0.44
DIPROVATE-N cream 16g (Fulford)$ 0.44
Diprovate-N Plus Betamethasone dipropionate0.05 % w/w, Neomycin sulphate0.5 % w/w, Zinc sulphate 0.5 %w/w. CRM / 15g (Ranbaxy)$ 0.79
15g (Ranbaxy)$ 0.79
DIPROVATE-N PLUS cream 15g (Ranbaxy)$ 0.79
E E N 5 mL
E E N 6 mL
EPHYTOL LOTION 1 bottle / 15 ML lotion each (Pasteur Laboratories Pvt Ltd)$ 0.71
EPHYTOL OINTMENT 1 tube / 20 GM ointment each (Pasteur Laboratories Pvt Ltd)$ 0.41
Ephytol Ointment (Pasteur Laboratories Pvt Ltd)$ 0.02
Eye Betason-N 3 g
Genelin 5 mL
Ibeth-N Betamethasone 0.1 %, Neomycin0.5 %. DPS / 5ml$ 0.25
5ml$ 0.25
Ibeth-N Betamethasone 0.1 %, neomycin0.5 %. EYE/EAR DPS / 5ml$ 0.25
Lieyecon 5 mL
Lieyecon 6 mL
Mekoderm-Neomycin 1 tube 10 g
Metaskin-N 10 g x 1's (Metiska)$ 1.49
MILBETA N 0.35%/0.1% DROPS 1 packet / 5 ML drop each (Sun Pharma Laboratories Ltd)$ 0.25

References

  1. DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "betamethasone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Conovate-N are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Conovate-N. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


2 consumers reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Conovate-N drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
50.0%
Not expensive1
50.0%


Consumer reported time for results

No survey data has been collected yet


3 consumers reported age

Users%
30-452
66.7%
16-291
33.3%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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