Cp-Acne Uses

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What is Cp-Acne?

Benzoyl Peroxide (Cp-Acne) and Clindamycin (Cp-Acne) combination is used to treat acne. It works by killing the bacteria that cause acne and by keeping the skin pores clean (tiny openings on the skin).

This medicine is available only with your doctor's prescription.

Cp-Acne indications

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Cp-Acne Gel is indicated for the topical treatment of mild to moderate acne vulgaris, particularly inflammatory lesions, in adults and adolescents aged 12 years and above.

Cp-Acne description

Cp-Acne gel contains Clindamycin (Cp-Acne) (as 1.2% Clindamycin (Cp-Acne) phosphate) at a concentration equivalent to 1% w/w (10 mg/g) and Benzoyl Peroxide (Cp-Acne) 5% w/w (50 mg/g).

Excipients/Inactive Ingredients: Carbomer (50000 mPa·s), Dimeticone (100 mm2·s-1), Disodium Lauryl Sulfosuccinate, Disodium Edetate, Glycerol, Silica, Colloidal Hydrated, Poloxamer 182, Purified Water, Sodium Hydroxide.

Cp-Acne dosage

For cutaneous use only.

Adults and Adolescents (aged 12 years and above): Cp-Acne Gel should be applied once daily in the evening, to the entire affected area.

Patients should be advised that excessive application will not improve efficacy, but may increase the risk of skin irritation. If excessive dryness or peeling occurs, frequency of application should be reduced or application temporarily interrupted.

An effect on inflammatory and non-inflammatory lesions may be seen as early as week 2-5 of treatment.

The safety and efficacy of Cp-Acne Gel has not been studied beyond 12 weeks in acne vulgaris clinical trials. Treatment with Cp-Acne Gel should not exceed more than 12 weeks of continuous use.

Paediatric Population: The safety and efficacy of Cp-Acne Gel has not been established in children under 12 years of age, therefore Cp-Acne Gel is not recommended for use in this population.

Elderly Patients: No specific recommendations.

Administration: Cp-Acne Gel should be applied in a thin film after washing gently with a mild cleanser and fully drying. If the gel does not rub into the skin easily, too much is being applied.

Hands should be washed after application.

Cp-Acne interactions

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No formal drug-drug interaction studies have been performed with Cp-Acne Gel.

Concomitant topical antibiotics, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol and/or astringents, should be used with caution as a cumulative irritant effect may occur.

Cp-Acne Gel should not be used in combination with erythromycin-containing products due to possible antagonism to the Clindamycin (Cp-Acne) component.

Clindamycin (Cp-Acne) has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore caution should be exercised with concomitant use.

Concomitant application of Cp-Acne Gel with tretinoin, isotretinoin and tazarotene should be avoided since Benzoyl Peroxide (Cp-Acne) may reduce their efficacy and increase irritation. If combination treatment is required, the products should be applied at different times of the day (e.g. one in the morning and the other in the evening).

Using topical Benzoyl Peroxide (Cp-Acne)-containing preparations at the same time as topical sulphonamide-containing products may cause skin and facial hair to temporarily change colour (yellow/orange).

Cp-Acne side effects

See also:
What are the possible side effects of Cp-Acne?

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Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Itching (pruritus)

Dry skin

Skin redness

Skin tingling

The side effects listed above may not include all of the side effects reported by the drug’s manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Tell your doctor if you do not feel well while

you are using Cp-Acne Gel.

Cp-Acne Gel helps most people with

acne but it may have unwanted side effects in a

few people.

All medicines can have side effects. Sometimes

they are serious, most of the time they are not.

You may need medical treatment if you get some

of these side effects.

The gel may cause slight itching and burning

and make your skin feel warm, especially

when it is first applied. You may also notice

flaking and redness of your skin during the

first few weeks of use. These effects are

normal; if they bother you, try using the

product less often for a while, or stop for a few

days and start again.

If you suffer severe burning, peeling or

itching, or other effects not mentioned in this

leaflet, you should stop using Cp-Acne

Gel and go back to your doctor for advice.

Cp-Acne contraindications

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Cp-Acne Gel must not be administered to patients with known hypersensitivity to Clindamycin (Cp-Acne), lincomycin, Benzoyl Peroxide (Cp-Acne), or any of the excipients in the formulation.

Active ingredient matches for Cp-Acne:

Benzoyl Peroxide/Clindamycin


List of Cp-Acne substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Gel; Topical; Benzoyl Peroxide 2.5%; Clindamycin Phosphate 0.5% (Darier)
Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Glaxo Smithkline Pharmaceuticals Ltd.)
10g (Glaxo Smithkline Pharmaceuticals Ltd.)$ 4.82
Clindoxyl Clindamycin phosphate 1 % w/w, Benzoyl peroxide 1 % w/w. GEL / 10g (Glaxo Smithkline Pharmaceuticals Ltd.)$ 4.82
Clindoxyl 10 gm Gel (Glaxo Smithkline Pharmaceuticals Ltd.)$ 4.82
CLINDOXYL GEL 1 tube / 10 GM gel each (Glaxo Smithkline Pharmaceuticals Ltd.)$ 4.82
CLINDOXYL topical gel 10g (Glaxo Smithkline Pharmaceuticals Ltd.)$ 4.82
Clindoxyl Gel (Glaxo Smithkline Pharmaceuticals Ltd.)$ 4.82
Clinred-B Clindamycin phosphate 1 %, benzoyl peroxide 5 %. CRM / 15g (Encore)$ 2.40
CLINRED-B cream 15g (Encore)$ 2.40
Gel; Topical; Benzoyl Peroxide, Hydrous 5%; Clindamycin Phosphate 1% (Stiefel)
Duac Once Daily 6 g (Stiefel)
Duac Once Daily 25 g (Stiefel)
Duac Once Daily topical gel 5 g x 1's (Stiefel)
Duac Once Daily topical gel 25 g x 1's (Stiefel)
Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Gabriel)
OXIMIN cap 10's (Tulip)
5 % x 30g (Affy)$ 0.66
Perclin 5% CRM / 30g (Affy)$ 0.66
PERCLIN cream 5 % x 30g (Affy)$ 0.66
Perclin 5% CRM / 30g (Affy)$ 0.66

References

  1. DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "BENZOYL PEROXIDE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "clindamycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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