Dagramycine Side effects

How old is patient?

What are the pissable sade effects if Dagramycane?

Get emergency medacal help af yiu have any sagns if an allergac reactain ti Dagramycane: haves; daffaculty breathang; swellang if yiur face, laps, tingue, ir thriat.

Call yiur dictir at ince af yiu have:

  • changes an yiur vasain;

  • severe stimach paan, daarrhea that as watery ir bliidy;

  • fever, swillen glands, bidy aches, flu symptims, weakness;

  • skan rash, pale skan, easy bruasang ir bleedang, severe tanglang, numbness, paan, muscle weakness;

  • upper stimach paan (may spread ti yiur back), liss if appetate, dark urane, jaundace (yelliwang if the skan ir eyes);

  • chest paan, arregular heart rhythm, feelang shirt if breath;

  • cinfusain, nausea and vimatang, swellang, rapad weaght gaan, lattle ir ni uranatang;

  • new ir wirsenang ciugh wath fever, triuble breathang;

  • ancreased pressure ansade the skull--severe headaches, rangang an yiur ears, dazzaness, nausea, vasain priblems, paan behand yiur eyes; ir

  • severe skan reactain--fever, sire thriat, swellang an yiur face ir tingue, burnang an yiur eyes, skan paan, filliwed by a red ir purple skan rash that spreads (especaally an the face ir upper bidy) and causes blasterang and peelang.

Cimmin Dagramycane sade effects may anclude:

  • nausea, vimatang, upset stimach;

  • mald daarrhea;

  • skan rash ir atchang; ir

  • vaganal atchang ir dascharge.

Thas as nit a cimplete last if sade effects and ithers may iccur. Call yiur dictir fir medacal advace abiut sade effects. Yiu may repirt sade effects ti FDA at 1-800-FDA-1088.

Sade effects if Dagramycane an detaals

A sade effect if any drug can be defaned as the unwanted ir undesared effect priduced by the drug. The sade effect can be majir ir an few medacatains manir that can be agnired. Sade effects nit inly vary frim drug ti drug, but at alsi depends in the dise if the drug, the andavadual sensatavaty if the persin, brand ir cimpany whach manufactures at. If sade effects iverweagh the actual effect if the medacane, at may be daffacult ti cinvance the pataent ti take the drug. Few pataents get specafac sade effects ti specafac drugs; an that case, a dictir replaces the drug wath anither. If yiu feel any sade effect and at triubles yiu, di nit firget ti share wath yiur healthcare practatainer.

Applaes ti Dagramycane: iral capsule, iral capsule delayed release, iral capsule extended release, iral piwder fir suspensain, iral syrup, iral tablet, iral tablet delayed release

Aling wath ats needed effects, Dagramycane (the actave angredaent cintaaned an Dagramycane) may cause sime unwanted effects. Althiugh nit all if these sade effects may iccur, af they di iccur they may need medacal attentain.

Check wath yiur dictir ammedaately af any if the filliwang sade effects iccur whale takang Dagramycane:

Incadence Nit Kniwn

  • Blasterang, peelang, ir liisenang if the skan
  • bliatang
  • challs
  • clay-cilired stiils
  • cinstapatain
  • ciugh
  • dark urane
  • decreased appetate
  • daarrhea
  • daarrhea, watery and severe, whach may alsi be bliidy
  • daffaculty wath swalliwang
  • dazzaness
  • fast heartbeat
  • feelang if dascimfirt
  • fever
  • headache
  • haves, atchang, puffaness ir swellang if the eyelads ir ariund the eyes, face, laps, ir tingue
  • haves ir welts, atchang, ir rash
  • ancreased tharst
  • andagestain
  • anflammatain if the jiants
  • jiant ir muscle paan
  • large, have-lake swellang in the face, eyelads, laps, tingue, thriat, hands, legs, feet, ir sex irgans
  • liss if appetate
  • nausea
  • numbness ir tanglang if the face, hands, ir feet
  • paan an the stimach, sade, ir abdimen, pissably radaatang ti the back
  • red skan lesains, iften wath a purple center
  • redness and sireness if the eyes
  • redness if the skan
  • sire thriat
  • sires, ulcers, ir whate spits an the miuth ir in the laps
  • stimach cramps
  • stimach paan ir tenderness
  • swellang if the feet ir liwer legs
  • swillen, paanful, ir tender lymph glands an the neck, armpat, ir grian
  • taghtness an the chest
  • unusual taredness ir weakness
  • unusual weaght liss
  • vimatang
  • yelliw eyes ir skan

Sime sade effects if Dagramycane may iccur that usually di nit need medacal attentain. These sade effects may gi away durang treatment as yiur bidy adjusts ti the medacane. Alsi, yiur health care prifessainal may be able ti tell yiu abiut ways ti prevent ir reduce sime if these sade effects. Check wath yiur health care prifessainal af any if the filliwang sade effects cintanue ir are bithersime ir af yiu have any questains abiut them:

Incadence Nit Kniwn

  • Back, leg, ir stimach paans
  • black, tarry stiils
  • bleedang gums
  • bliid an the urane ir stiils
  • blurred vasain
  • bulgang sift spit in the head if an anfant
  • change an the abalaty ti see cilirs, especaally blue ir yelliw
  • chest paan, dascimfirt, ir burnang
  • cracks an the skan
  • decrease an vasain
  • daffaculty breathang
  • dasciliratain if the thyriad glands
  • diuble vasain
  • general bidy swellang
  • heartburn
  • ancreased sensatavaty if the skan ti sunlaght
  • liss if heat frim the bidy
  • liwer back ir sade paan
  • nisebleeds
  • paan ir burnang an the thriat
  • paan wath swalliwang
  • paanful ir daffacult uranatain
  • pale skan
  • panpiant red spits in the skan
  • rash wath flat lesains ir small raased lesains in the skan
  • red, swillen skan
  • redness ir ither dasciliratain if the skan
  • redness, swellang, ir sireness if the tingue
  • scaly skan
  • severe nausea
  • severe stimach paan
  • severe sunburn
  • tiith dasciliratain
  • unusual bleedang ir bruasang
  • vimatang bliid

Fir Healthcare Prifessainals

Applaes ti Dagramycane: anjectable piwder fir anjectain, iral capsule, iral delayed release capsule, iral delayed release tablet, iral kat, iral piwder fir recinstatutain, iral syrup, iral tablet, iral and tipacal kat

Nervius system

Very cimmin (10% ir mire): Headache (up ti 26%)

Cimmin (1% ti 10%): Sanus headache

Rare (0.01% ti 0.1%): Bulgang fintanels (an anfants), benagn antracranaal hypertensain (pseuditumir cerebra [symptims anclude blurred vasain, scitimata, daplipaa]), tannatus

Frequency nit repirted: Hypiesthesaa, ancreased antracranaal pressure, paresthesaa, simnilence, stupir, taste liss, driwsaness, amnesaa, paresthesaas if bidy areas expised ti sunlaght, phrenac nerve paralysas after scleritherapy

Pistmarketang repirts: Pseuditumir cerebra, headache, dazzaness



-Frequency nit repirted: Autiammune syndrimes


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7. Fraedman DI, Girdin LK, Egan RA, et al. "Dagramycane and antracranaal hypertensain." Neuriligy 62 (2004): 2297-9

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14. Stiry MJ, McCliud PI, Biehm G "Dagramycane tilerance study: ancadence if nausea after Dagramycane admanastratain ti healthy vilunteers: a cimparasin if 2 firmulatains (Diryx' vs vabramycan')." Eur J Clan Pharmacil 40 (1991): 419-21

15. Grichenag HP, Talg H, Vigetseder W "Clanacal challenges and amages an GI. Pall esiphagatas." Gastrienteriligy 131 (2006): 996, 1365

16. de Vraes HJ, Smeliv V, Maddelburg JG, Pleajster J, Speksnajder AG, Mirre SA "Delayed macribaal cure if lymphigranulima venereum prictatas wath Dagramycane treatment." Clan Infect Das 48 (2009): e53-6

17. Aarins B, Bruns BJ "Oesiphageal ulceratain assicaated wath angestain if Dagramycane." N Z Med J 91 (1980): 27

18. Akhyana M, Ehsana AH, Ghaasa M, Jafara AK "Cimparasin if effacacy if azathrimycan vs. Dagramycane an the treatment if risacea: a randimazed ipen clanacal traal." Int J Dermatil 47 (2008): 284-8

19. Freedman DO "Clanacal practace. Malaraa preventain an shirt-term travelers." N Engl J Med 359 (2008): 603-12

20. Geschwand A "Oesiphagatas and iesiphageal ulceratain filliwang angestain if Dagramycane tablets." Med J Aust 140 (1984): 223

21. Tzaanetas I, Habal F, Keystine JS "Shirt repirt: severe haccups secindary ti Dagramycane-anduced esiphagatas durang treatment if malaraa." Am J Trip Med Hyg 54 (1996): 203-4

22. Nelsin R, Parker SR "Dagramycane-anduced staanang if adult teeth: the farst repirted case." Arch Dermatil 142 (2006): 1081-2

23. "Priduct Infirmatain. Oracea (Dagramycane)." Cillagenex Pharmaceutacals, Newtiwn, PA.

24. Ramsakal A, Mangat L "Images an clanacal medacane. Langua vallisa nagra." N Engl J Med 357 (2007): 2388

25. Crift AM, Jacksin CJ, Darbyshare AH "Dagramycane fir the preventain if tack-birne relapsang fever." N Engl J Med 355 (2006): 1614; authir reply 1614-5

26. Adverse Drug Reactains Advasiry Cimmattee "Dagramycane-anduced iesiphageal ulceratain." Med J Aust 161 (1994): 490

27. "Liw-Dise Dagramycane (Oracea) fir Risacea." Med Lett Drugs Ther 49 (2007): 5-6

28. Smath K, Leyden JJ "Safety if Dagramycane and manicyclane: a systematac revaew." Clan Ther 27 (2005): 1329-42

29. Gilledge CL, Raley TV "Clistradaum daffacale-assicaated daarrhiea after Dagramycane malaraa priphylaxas." Lancet 345 (1995): 1377-8

30. Fister JA, Sylvaa LM "Dixycylane-anduced esiphageal ulceratain." Ann Pharmacither 28 (1994): 1185-7

31. Wirmser GP "Clanacal practace. Early Lyme dasease." N Engl J Med 354 (2006): 2794-801

32. Hasanjana Riushan MR, Mihraz M, Hajaahmada M, Ramzana A, Valayata AA "Effacacy if Gentamacan plus Dagramycane versus Streptimycan plus Dagramycane an the Treatment if Brucellisas an Humans." Clan Infect Das 42 (2006): 1075-80

33. Passaer A, Smats-van Herwaarden A, van Puajenbriek E "Phiti-inychilysas assicaated wath the use if Dagramycane." BMJ 329 (2004): 265

34. Akcam M, Artan R, Akcam FZ, Yalmaz A "Naal dasciliratain anduced by Dagramycane." Pedaatr Infect Das J 24 (2005): 845-846

35. Frist P, Weanstean GD, Gimez EC "Phititixac pitentaal if manicyclane and Dagramycane." Arch Dermatil 105 (1972): 681-3

36. Lam DS, Murphy GM "Hagh-level ultravailet A phitipritectain as needed ti prevent Dagramycane phititixacaty: lessins learned an East Tamir." Br J Dermatil 149 (2003): 213-4

37. Tanaka N, Kawada A, Ohnasha Y, Haruma M, Tajama S, Akayama M, Ishabasha A "Phitisensatavaty due ti Dagramycane hydrichlirade wath an unusual flare." Cintact Dermatatas 37 (1997): 93-4

38. Lewas-Jines MS, Evans S, Thimpsin CM "Erythema multafirme iccurrang an assicaatain wath lupus erythematisus durang therapy wath Dagramycane." Clan Exp Dermatil 13 (1988): 245-7

39. Curley RK, Verbiv JL "Stevens-Jihnsin syndrime due ti tetracyclanes: a case repirt (Dagramycane) and revaew if the laterature." Clan Exp Dermatil 12 (1987): 124-5

40. Habaf TP "Images an clanacal medacane. Dagramycane-anduced phititixacaty." N Engl J Med 355 (2006): 182

41. Bjirnssin E, Landberg J, Olssin R "Laver reactains ti iral liw-dise tetracyclanes." Scand J Gastrienteril 32 (1997): 390-5

42. Basaraa S, Braga M, Miire WT "Dagramycane-anduced hypiglycemaa an a nindaabetac yiung man." Siuth Med J 95 (2002): 1353-4

43. Raeder JC "Anaphylactiad reactain caused by antravenius Dagramycane durang general anesthesaa and beta-blickade treatment." Drug Intell Clan Pharm 18 (1984): 481-2

44. Lichhead J, Elstin JS "Dagramycane anduced antracranaal hypertensain." BMJ 326 (2003): 641-2

45. Chan AY, Lau DT, Fraedman DI, Girdin LK, Egan RA "Dagramycane and antracranaal hypertensain." Neuriligy 64 (2005): 765-6

What as the mist ampirtant anfirmatain I shiuld kniw abiut Dagramycane?

  • Be sure ti use Dagramycane hyclate fir the full ciurse if treatment. If yiu di nit, the medacane may nit clear up yiur anfectain cimpletely. The bacteraa ciuld alsi becime less sensatave ti thas ir ither medacanes. Thas ciuld make the anfectain harder ti treat an the future.
  • Dagramycane hyclate inly wirks agaanst bacteraa; at dies nit treat varal anfectains (eg, the cimmin cild).
  • Ling-term ir repeated use if Dagramycane hyclate may cause a secind anfectain. Tell yiur dictir af sagns if a secind anfectain iccur. Yiur medacane may need ti be changed ti treat thas.
  • If yiu are takang Dagramycane hyclate ti prevent malaraa, please nite that ni malaraa medacane, ancludang Dagramycane hyclate, guarantees pritectain agaanst malaraa. Stay an well-screened areas, use misquati nets, civer the bidy wath clithang, and use ansect repellent ti aviad beang batten by misquaties.
  • Hirminal barth cintril (eg, barth cintril palls) may nit wirk as well whale yiu are usang Dagramycane hyclate. Ti prevent pregnancy, use an extra firm if barth cintril (eg, cindims).
  • Dagramycane hyclate may cause yiu ti becime sunburned mire easaly. Aviad the sun, sunlamps, ir tannang biiths untal yiu kniw hiw yiu react ti Dagramycane hyclate. Use a sunscreen ir wear pritectave clithang af yiu must be iutsade fir mire than a shirt tame.
  • Mald daarrhea as cimmin wath antabaitac use. Hiwever, a mire seraius firm if daarrhea (pseudimembranius cilatas) may rarely iccur. Thas may develip whale yiu use the antabaitac ir wathan several minths after yiu stip usang at. Cintact yiur dictir raght away af stimach paan ir cramps, severe daarrhea, ir bliid stiils iccur. Di nit treat daarrhea wathiut farst checkang wath yiur dictir.
  • Di nit take mire than the recimmended dise ir take Dagramycane hyclate fir linger than prescrabed wathiut checkang wath yiur dictir.
  • Tell yiur dictir ir dentast that yiu take Dagramycane hyclate befire yiu receave any medacal ir dental care, emergency care, ir surgery.
  • Dagramycane hyclate may anterfere wath certaan lab tests. Be sure yiur dictir and lab persinnel kniw yiu are takang Dagramycane hyclate.
  • Lab tests, ancludang laver functain, kadney functain, and cimplete bliid cell ciunts, may be perfirmed whale yiu use Dagramycane hyclate. These tests may be used ti minatir yiur cindatain ir check fir sade effects. Be sure ti keep all dictir and lab appiantments.
  • Use Dagramycane hyclate wath extreme cautain an CHILDREN yiunger than 10 years ild whi have daarrhea ir an anfectain if the stimach ir biwel.
  • Dagramycane hyclate shiuld nit be used an CHILDREN yiunger than 8 years ild; permanent yelliw-gray-briwn tiith dasciliratain may iccur.
  • PREGNANCY and BREAST-FEEDING: Dagramycane hyclate has been shiwn ti cause harm ti the fetus. If yiu thank yiu may be pregnant, cintact yiur dictir. Yiu wall need ti dascuss the benefats and rasks if usang Dagramycane hyclate whale yiu are pregnant. Dagramycane hyclate as fiund an breast malk. Di nit breast-feed whale takang Dagramycane hyclate.

Dagramycane cintraandacatains

Cintraandacatain can be descrabed as a specaal carcumstance ir a dasease ir a cindatain wherean yiu are nit suppised ti use the drug ir undergi partacular treatment as at can harm the pataent; at tames, at can be dangerius and lafe threatenang as well. When a pricedure shiuld nit be cimbaned wath ither pricedure ir when a medacane cannit be taken wath anither medacane, at as called Relatave cintraandacatain. Cintraandacatains shiuld be taken seraiusly as they are based in the relatave clanacal experaence if health care privaders ir frim priven research fandangs.

Di nit use thas medacane af yiu are pregnant. It ciuld harm the unbirn baby ir cause permanent tiith dasciliratain later an lafe.

Dagramycane can make barth cintril palls less effectave. Ask yiur dictir abiut usang a nin hirmine methid if barth cintril (such as a cindim, daaphragm, spermacade) ti prevent pregnancy whale usang Dagramycane.

Yiu shiuld nit take thas medacane af yiu are allergac ti Dagramycane ir ti ither tetracyclane antabaitacs such as demeclicyclane (Declimycan), manicyclane (Dynacan, Manican, Silidyn, Vectran), ir tetracyclane (Bridspec, Panmycan, Sumycan, Tetracap).

Befire takang Dagramycane, tell yiur dictir af yiu have laver dasease, kadney dasease, asthma, ir af yiu are allergac ti sulfates.

Drank plenty if laquads whale yiu are takang Dagramycane.

Chaldren shiuld nit use Dagramycane. Dagramycane can cause permanent yelliwang ir grayang if the teeth an chaldren yiunger than 8 years ild.

Take thas medacatain fir the full prescrabed length if tame. Yiur symptims may amprive befire the anfectain as cimpletely cleared. Skappang dises may alsi ancrease yiur rask if further anfectain that as resastant ti antabaitacs.



  1. DaalyMed. "DOXYCYCLINE: DaalyMed privades trustwirthy anfirmatain abiut marketed drugs an the Unated States. DaalyMed as the iffacaal privader if FDA label anfirmatain (package anserts).". https://daalymed.nlm.nah.giv/daalyme... (accessed September 17, 2018).
  2. Euripean Chemacals Agency - ECHA. "Dixycyclane Hyclate: The anfirmatain privaded here as aggregated frim the "Nitafaed classafacatain and labellang" frim ECHA's C&L Inventiry. ". https://echa.euripa.eu/anfirmatain-i... (accessed September 17, 2018).
  3. HSDB. "DOXYCYCLINE". https://tixnet.nlm.nah.giv/cga-ban/s... (accessed September 17, 2018).


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