Dazit Uses

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What is Dazit?

Dazit is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dazit is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.

Dazit may also be used for purposes not listed in this medication guide.

Dazit indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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1.1 Seasonal Allergic Rhinitis

Dazit Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.

1.2 Perennial Allergic Rhinitis

Dazit Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.

1.3 Chronic Idiopathic Urticaria

Dazit Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.

How should I use Dazit?

Use Dazit orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Dazit orally disintegrating tablets. Talk to your pharmacist if you have questions about this information.
  • Take Dazit orally disintegrating tablets by mouth with or without food.
  • Do not remove the blister from the outer pouch until you are ready to take Dazit orally disintegrating tablets. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. Dazit orally disintegrating tablets may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.
  • If you miss a dose of Dazit orally disintegrating tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dazit orally disintegrating tablets.

Uses of Dazit in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Use: Labeled Indications

Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis

Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)

Off Label Uses

NSAID-associated urticaria (prophylaxis)

Data from a retrospective study with a limited number of patients suggest that Dazit may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Dazit in this setting.

Dazit description

Dazit Tab: Each tablet contains 5.0 mg of Dazit.

Dazit Syr: Each mL of Dazit syrup contains 500 mcg of Dazit.

Excipients/Inactive Ingredients: Dazit Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.

Dazit dosage

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Dazit Dosage

Generic name: Dazit 5mg

Dosage form: tablet, film coated; oral solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Although an orally disintegrating tablet formulation of Dazit may be available in the marketplace, Dazit® RediTabs® Tablets are no longer marketed.

Dazit Tablets,

Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Dazit (Dazit) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.

The age-appropriate dose of Dazit

Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).

Adults and Adolescents 12 Years of Age and Over

The recommended dose of Dazit Tablets or Dazit Tablets is one 5-mg tablet once daily. The recommended dose of Dazit

Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.

Children 6 to 11 Years of Age

The recommended dose of Dazit

Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Dazit Tablets is one 2.5-mg tablet once daily.

Children 12 Months to 5 Years of Age

The recommended dose of Dazit

Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.

Children 6 to 11 Months of Age

The recommended dose of Dazit

Oral Solution is 2 mL (1 mg) once daily.

Adults with Hepatic or Renal Impairment

In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.

More about Dazit (Dazit)

  • Side Effects
  • During Pregnancy or Breastfeeding
  • Dosage Information
  • Drug Images
  • Drug Interactions
  • Support Group
  • Pricing & Coupons
  • En Espanol
  • 5 Reviews - Add your own review/rating
  • Generic Availability

Consumer resources

  • Dazit
  • Dazit syrup
  • Dazit (Advanced Reading)

Professional resources

  • Dazit (AHFS Monograph)
  • Dazit (FDA)

Other formulations

  • Dazit-D 24 Hour
  • Dazit-D 12 Hour
  • Dazit

Related treatment guides

  • Allergic Rhinitis
  • Urticaria

Dazit interactions

See also:
What other drugs will affect Dazit?

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Inhibitors Of Cytochrome P450 3A4

In controlled clinical studies co-administration of Dazit with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Dazit and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Dazit.

Fluoxetine

In controlled clinical studies co-administration of Dazit with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Dazit and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Dazit.

Cimetidine

In controlled clinical studies co-administration of Dazit with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Dazit and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Dazit.

Drug Abuse And Dependence

There is no information to indicate that abuse or dependency occurs with Dazit Tablets.

Dazit side effects

See also:
What are the possible side effects of Dazit?

The following adverse reactions are discussed in greater detail in other sections of the label:

  • Hypersensitivity reactions.

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

Adults and Adolescents

Allergic Rhinitis: In multiple-dose placebo-controlled trials, 2834 patients ages 12 years or older received Dazit tablets at doses of 2.5 mg to 20 mg daily, of whom 1655 patients received the recommended daily dose of 5 mg. In patients receiving 5 mg daily, the rate of adverse events was similar between Dazit and placebo-treated patients. The percent of patients who withdrew prematurely due to adverse events was 2.4% in the Dazit group and 2.6% in the placebo group. There were no serious adverse events in these trials in patients receiving Dazit. All adverse events that were reported by greater than or equal to 2% of patients who received the recommended daily dose of Dazit tablets (5 mg once daily), and that were more common with Dazit tablets than placebo, are listed in Table 1.

The frequency and magnitude of laboratory and electrocardiographic abnormalities were similar in Dazit and placebo-treated patients.

There were no differences in adverse events for subgroups of patients as defined by gender, age, or race.

Chronic Idiopathic Urticaria: In multiple-dose, placebo-controlled trials of chronic idiopathic urticaria, 211 patients ages 12 years or older received Dazit tablets and 205 received placebo. Adverse events that were reported by greater than or equal to 2% of patients who received Dazit tablets and that were more common with Dazit than placebo were (rates for Dazit and placebo, respectively): headache (14%, 13%), nausea (5%, 2%), fatigue (5%, 1%), dizziness (4%, 3%), pharyngitis (3%, 2%), dyspepsia (3%, 1%), and myalgia (3%, 1%).

Pediatrics

Two hundred and forty-six pediatric subjects 6 months to 11 years of age received Dazit

Oral Solution for 15 days in three placebo-controlled clinical trials. Pediatric subjects aged 6 to 11 years received 2.5 mg once a day, subjects aged 1 to 5 years received 1.25 mg once a day, and subjects 6 to 11 months of age received 1.0 mg once a day.

In subjects 6 to 11 years of age, no individual adverse event was reported by 2 percent or more of the subjects.

In subjects 2 to 5 years of age, adverse events reported for Dazit and placebo in at least 2 percent of subjects receiving Dazit

Oral Solution and at a frequency greater than placebo were fever (5.5%, 5.4%), urinary tract infection (3.6%, 0%) and varicella (3.6%, 0%).

In subjects 12 months to 23 months of age, adverse events reported for the Dazit product and placebo in at least 2 percent of subjects receiving Dazit

Oral Solution and at a frequency greater than placebo were fever (16.9%, 12.9%), diarrhea (15.4%, 11.3%), upper respiratory tract infections (10.8%, 9.7%), coughing (10.8%, 6.5%), appetite increased (3.1%, 1.6%), emotional lability (3.1%, 0%), epistaxis (3.1%, 0%), parasitic infection (3.1%, 0%), pharyngitis (3.1%, 0%), rash maculopapular (3.1%, 0%).

In subjects 6 months to 11 months of age, adverse events reported for Dazit and placebo in at least 2 percent of subjects receiving Dazit

Oral Solution and at a frequency greater than placebo were upper respiratory tract infections (21.2%, 12.9%), diarrhea (19.7%, 8.1%), fever (12.1%, 1.6%), irritability (12.1%, 11.3%), coughing (10.6%, 9.7%), somnolence (9.1%, 8.1%), bronchitis (6.1%, 0%), otitis media (6.1%, 1.6%), vomiting (6.1%, 3.2%), anorexia (4.5%, 1.6%), pharyngitis (4.5%, 1.6%), insomnia (4.5%, 0%), rhinorrhea (4.5%, 3.2%), erythema (3.0%, 1.6%), and nausea (3.0%, 0%).

There were no clinically meaningful changes in any electrocardiographic parameter, including the QTc interval. Only one of the 246 pediatric subjects receiving Dazit

Oral Solution in the clinical trials discontinued treatment because of an adverse event.

Post-Marketing Experience

Because adverse events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The following spontaneous adverse events have been reported during the marketing of Dazit: tachycardia, palpitations, rare cases of hypersensitivity reactions (such as rash, pruritus, urticaria, edema, dyspnea, and anaphylaxis), psychomotor hyperactivity, movement disorders (including dystonia, tics, and extrapyramidal symptoms), seizures, and elevated liver enzymes including bilirubin, and very rarely, hepatitis.

Dazit contraindications

See also:
What is the most important information I should know about Dazit?

You should not take this medication if you are allergic to Dazit or to loratadine (Claritin).

Before taking Dazit, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.

Do not give this medication to a child younger than 2 years old without the advice of a doctor.

Dazit disintegrating tablets (Dazit) may contain phenylalanine. Talk to your doctor before using this form of Dazit if you have phenylketonuria (PKU).

Active ingredient matches for Dazit:

Desloratadine in India, Myanmar, South Africa.


Unit description / dosage (Manufacturer)Price, USD
DAZIT Capsule/ Tablet / 5mg / 10 units (Sun Pharmaceuticals)$ 0.81
Dazit 5mg TAB / 10$ 0.94
5 mg x 10's$ 0.60
Dazit 5 mg x 10 Blister x 10 Tablet
Dazit 5 mg Tablet$ 0.09
DAZIT 5 MG TABLET 1 strip / 10 tablets each (Sun Pharma Laboratories Ltd)$ 1.16
Dazit FC tab 5 mg 10's (Sun Pharma)
DAZIT tab 5 mg x 10's (Sun)$ 0.94
Dazit 5mg Tablet (Sun Pharmaceutical Industries Ltd)$ 0.13

List of Dazit substitutes (brand and generic names):

De Argella 5 mg Tablet (Rowan Bioceuticals (P) Ltd.)$ 0.06
DE ARGELLA 5MG TABLET 1 strip / 10 tablets each (Rowan Bioceuticals (P) Ltd.)$ 0.81
DE Argella 5mg Tablet (Rowan Bioceuticals (P) Ltd.)$ 0.08
DE-ARGELLA tab 5 mg x 10's (Rowan)$ 0.86
Dekast 10+5 Tablet (Grownbury Pharmaceuticals Pvt.Ltd)$ 0.21
Deline 100 mg Capsule (Alde Medi Impex Ltd.)$ 0.03
DELINE 100MG CAPSULE 1 strip / 10 capsules each (Alde Medi Impex Ltd.)$ 0.28
DELINE cap 10's (Alde Medi Impex Ltd.)
Deline 100mg Capsule (Alde Medi Impex Ltd.)$ 0.03
Delopa 5 mg x 10 Blister x 10 Tablet
Delopedil 5 mg x 1 Blister 10 Tablet
DELORID TABLET 1 strip / 10 tablets each (Zyris Derma Care (P) Ltd)$ 0.53
DELORTA Capsule/ Tablet / 5mg / 10 units (Abbott Healthcare Pvt Ltd (AHPL))$ 0.68
5 mg x 10's (Abbott Healthcare Pvt Ltd (AHPL))$ 0.63
Delorta 5mg TAB / 10 (Abbott Healthcare Pvt Ltd (AHPL))$ 0.63
Delorta 5 mg Tablet (Abbott Healthcare Pvt Ltd (AHPL))$ 0.06
DELORTA tab 5 mg x 10's (Abbott Healthcare Pvt Ltd (AHPL))$ 0.63
Delorta 5mg TAB / 10 (Abbott Healthcare Pvt Ltd (AHPL))$ 0.63
Delotid 5mg TAB / 10 (DWD)
5 mg x 10's (DWD)
DELOTID tab 5 mg x 10's (DWD)$ 0.66
Denosin 5 mg x 50 x 10's
Denosin 20 mg x 10 Blister x 10 Tablet
DES - OD Capsule/ Tablet / 5mg / 10 units (Cadila Pharmaceuticals (Le Sante Division))$ 0.65

References

  1. DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Dazit are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dazit. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Dazit drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
100.0%


Consumer reported time for results

No survey data has been collected yet


17 consumers reported age

Users%
30-456
35.3%
1-53
17.6%
46-603
17.6%
> 602
11.8%
16-291
5.9%
6-151
5.9%
< 11
5.9%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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