Deanxit Uses

Rating: 2.5 - 2 review(s)
How do you administer this medicine?
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Deanxit indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Anxiety, depression, asthenia. Psychogenic depressions, depressive neuroses. Masked depression. Psychosomatic affections accompanied by anxiety & apathy. Menopausal depression.

Deanxit description

Each tablet contains Flupentixol (Deanxit) (as dihydrochloride) 0.5 mg and Melitracen (Deanxit) (as hydrochloride) 10 mg.

Deanxit also contains the following excipients: Tablet Core: Lactose monohydrate, potato starch, talc, gelatin, magnesium stearate. Coating: Gelatin, sucrose, sucrose powder, Deanxit colour (erythrosine E127 and indigotine E132). Polishing Wax: Capol 1295 (a mixture of beeswax, white and carnauba wax).

Deanxit dosage

Adults: Usually 2 tablets daily, morning and noon. In severe cases, the morning dose may be increased to 2 tablets. Maximum Dose: 4 tablets daily.

Elderly (>65 years): 1 tablet in the morning. In severe cases, 1 tablet in the morning and 1 at noon.

Maintenance Dose: Usually 1 tablet in the morning.

In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.

Reduced Renal and Liver Function: Deanxit can be given in the recommended doses.

Administration: The tablets are swallowed with water.

Deanxit interactions

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Contraindicated Combinations: Monoamine oxidase inhibitors [nonselective as well as selective A (moclobemide) and B (selegiline)], risk of "serotonin syndrome".

Inadvisable Combinations: Sympathomimetic Agents: Melitracen (Deanxit) may potentiate the cardiovascular effects of adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine and phenylpropanolamine (eg, as contained in local and general anaesthetics and nasal decongestants).

Adrenergic Neurone Blockers: Deanxit may counteract the antihypertensive effects of guanethidine, betanidine, reserpine, clonidine and methyldopa. It is advisable to review all antihypertensive therapy during treatment with tricyclic antidepressants.

Anticholinergic Agents: Tricyclic antidepressants may potentiate the effects of these drugs on the eye, central nervous system (CNS), bowel and bladder; concomitant use of these should be avoided due to an increased risk of paralytic ileus, hyperpyrexia.

Drugs Which May Increase the QT Interval: Increases in the QT interval related to antipsychotic treatment may be exacerbated by the co-administration of other drugs known to significantly increase the QT interval. Co-administration of such drugs should be avoided. Relevant classes include: Class Ia and III antiarrhythmics (eg, quinidine, amiodarone, sotalol, dofetilide); some antipsychotics (eg, thioridazine); some macrolides (eg, erythromycin); some antihistamine (eg, terfenadine, astemizole); some quinolone antibiotics (eg, gatifloxacin, moxifloxacin).

The list mentioned is not exhaustive and other individual drugs known to significantly increase QT interval (eg, cisapride, lithium) should be avoided.

Drugs known to cause electrolyte disturbances eg, thiazide diuretica (hypokalaemia) and drugs known to increase the plasma concentration of Flupentixol (Deanxit) should also be used with caution as they may increase the risk of QT prolongation and malignant arrhythmias.

Combinations Requiring Precautions for Use: Central Nervous System Depressants: Deanxit may enhance the effects of alcohol, barbiturates and other CNS depressants.

Lithium: Concomitant use of Deanxit and lithium increases the risk of neurotoxicity.

Levodopa: Deanxit may reduce the effect of levodopa and increase the risk of cardiac side effects.

Incompatibilities: Not applicable.

Deanxit side effects

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Dryness of the mouth, dizziness, tremor, nervousness, blurred vision and insomnia are the most frequent adverse effects and occur commonly.

In the listing as follows, the following convention is used: MedDRA system organ class or preferred term.

Frequencies are defined as: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); or not known (cannot be estimated from available data).

Post-Marketing: Isolated cases of cholestatic hepatitis have been reported.

Reporting of Suspected Adverse Reactions: Reporting of suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system.

Deanxit contraindications

Hypersensitivity to Flupentixol (Deanxit) or Melitracen (Deanxit) or to any of the excipients of Deanxit.

Circulatory collapse, depressed level of consciousness due to any cause (eg, intoxication with alcohol, barbiturates or opiates), coma, blood disorders, phaeochromocytoma.

Recent myocardial infarction. Any degree of atrioventricular block or disorders of cardiac rhythm and coronary artery insufficiency.

Concomitant treatment with monoamine oxidase inhibitors (MAOIs) is contraindicated. Simultaneous administration of Melitracen (Deanxit) and MAOIs may cause serotonin syndrome (a combination of symptoms, possibly including agitation, confusion, tremor, myoclonus and hyperthermia).

As with other tricyclic antidepressants, Melitracen (Deanxit) should not be given to patients receiving MAOIs. Treatment with Deanxit may be instituted 14 days after discontinuation of nonselective MAOIs and minimum 1 day after discontinuation of moclobemide and selegiline. Treatment with MAOIs may be introduced 14 days after discontinuation of Deanxit.



Active ingredient matches for Deanxit:

Flupentixol/Melitracen in Austria, Bangladesh, Belgium, Bulgaria, China, Hong Kong, Luxembourg, Malta, Singapore, Spain, Switzerland, Taiwan, Thailand.

Flupenthixol/Flupentixol/Flupentixol Decanoate/Melitracen/Melitracen Hcl

Flupenthixol/melitracen in Singapore.

Flupentixol hydrochloride/melitracen hydrochloride in Spain, Switzerland, Belgium, Austria, Hong Kong, Thailand, Singapore, Italy.


Unit description / dosage (Manufacturer)Price, USD
Dragee; Oral; Flupentixol Hydrochloride 0.5 mg; Melitracen Hydrochloride 10 mg
Deanxit 10 x 10's
Deanxit 100's
Deanxit 0.5 mg x 5 Blister x 10 Tablet
Deanxit Flupentixol 0.5mg, melitracen10mg TAB / 10$ 0.79
10's$ 0.79
Deanxit 10+0.5 Tablet$ 0.09
DEANXIT 0.5 MG/10 MG TABLET 1 strip / 10 tablets each (Lundbeck India Pvt Ltd)$ 1.12
Deanxit tab 10 x 10's (Lundbeck)
Deanxit tab 100's (Lundbeck)

List of Deanxit substitutes (brand and generic names):

Danxipress 500's
Delewal flupentixol, melitracen TAB / 10$ 0.79
10's$ 0.79
Denxol Flupentixol 0.5 mg, Melitracen10 mg. TAB / 10 (La Pharmaceuticals)$ 0.55
10's (La Pharmaceuticals)$ 0.55
Denxol 10+0.5 Tablet (La Pharmaceuticals)$ 0.06
DENXOL 0.5MG/10MG TABLET 1 strip / 10 tablets each (La Pharmaceuticals)$ 0.56
Denxol 0.5 mg/10 mg Tablet (La Pharmaceuticals)$ 0.06
Desblue
Dexit Flupentixol 0.5 mg, Melitracen10 mg. TAB / 10 (Daksh Pharma)$ 0.73
10's (Daksh Pharma)$ 0.73
Dexit 10+0.5 Tablet (Daksh Pharma)$ 0.07
EQULOK 0.5MG/10MG TABLET 1 strip / 10 tablets each (Kanad Labs)$ 0.80
Equlok 0.5 mg/10 mg Tablet (Kanad Labs)$ 0.08
Exzilor Flupenthixol 0.5 mg, Melitracen 10 mg. TAB / 10$ 0.68
10's$ 0.68
Flebixen Flupentixol 0.5 mg, melitracen10 mg. TAB / 10$ 0.79
FLUANXIT TABLET 1 strip / 10 tablets each (Theo Pharma)$ 0.53
FLUANXIT tab 0.5 mg x 10's (Theo Pharma)$ 0.50
FLUFORD M TABLET 1 strip / 10 tablets each (Oxford Pharmaceuticals Pvt Ltd)$ 0.78
FLUMEL 0.5MG/10MG TABLET 1 strip / 10 tablets each (Parasol Laboratories)$ 0.77
Flumel 0.5 mg/10 mg Tablet (Parasol Laboratories)$ 0.08
Flunxit Flupentixol 0.5mg, Melitracen10mg TAB / 10 (Invision Medi Sciences)$ 0.78
10's (Invision Medi Sciences)$ 0.78
Flunxit 10+0.5 Tablet (Invision Medi Sciences)$ 0.08
Flupen-M Flupentixol 0.5mg, melitracen10mg TAB / 10$ 0.71
10's$ 0.71
Flupen-M Flupentixol 0.5mg, melitracen10mg TAB / 10$ 0.71

References

  1. PubChem. "Flupentixol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Flupentixol". http://www.drugbank.ca/drugs/DB00875 (accessed September 17, 2018).
  3. MeSH. "Antipsychotic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Deanxit are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Deanxit. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Deanxit drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Not useful1
100.0%


3 consumers reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Deanxit drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive2
66.7%
Expensive1
33.3%


7 consumers reported time for results

To what extent do I have to use Deanxit before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 5 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Deanxit. To get the time effectiveness of using Deanxit drug by other patients, please click here.
Users%
5 days2
28.6%
1 day2
28.6%
> 3 month2
28.6%
3 month1
14.3%


28 consumers reported age

Users%
16-2912
42.9%
30-456
21.4%
46-603
10.7%
< 12
7.1%
> 602
7.1%
6-152
7.1%
1-51
3.6%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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