Demoton-B12 Actions

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Actions of Demoton-B12 in details

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Pharmacology: Cyanocobalamin (Demoton-B12) acts as a coenzyme for fat and carbohydrate metabolism. It is essential for growth, cell replication, hematopoiesis and nucleoprotein and myelin synthesis. Thiamine (Demoton-B12) pyrophosphate and pyridoxal phosphate, the physiologically active form of Thiamine (Demoton-B12) and Pyridoxine (Demoton-B12) respectively, act as coenzymes for various metabolic functions affecting protein, carbohydrate and lipid metabolism. The B vitamins are readily absorbed orally except in malabsorption syndromes. It is metabolized in the liver and excreted via the kidneys.

Demoton-B12 pharmacology

It is thought that the mechanism of action of Thiamine (Demoton-B12) on endothelial cells is related to a reduction in intracellular protein glycation by redirecting the glycolytic flux.

References

  1. DailyMed. "ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. NCIt. "Thiamine: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
  3. EPA DSStox. "Thiamine ion: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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