Depo-Testosterone Cypionate Uses

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What is Depo-Testosterone Cypionate?

Depo-Testosterone Cypionate injection is used for the treatment of men whose bodies do not make enough natural Depo-Testosterone Cypionate, a condition called hypogonadism. Depo-Testosterone Cypionate is a male hormone responsible for the growth and development of the male sex organs and maintenance of secondary sex characteristics.

Depo-Testosterone Cypionate injection is also used in women with breast cancer that has spread to other parts of the body (metastatic).

Depo-Testosterone Cypionate injection is also used to stimulate delayed puberty in male teenagers.

This medicine is to be given only by or under the direct supervision of your doctor. The Depo-Testosterone Cypionate® brand is only available under a restricted distribution program called the Depo-Testosterone Cypionate® REMS program.

Depo-Testosterone Cypionate indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Males

Depo-Testosterone Cypionate® (Depo-Testosterone Cypionate Enanthate Injection, USP) is indicated for replacement therapy in conditions associated with a deficiency or absence of endogenous Depo-Testosterone Cypionate.

Primary hypogonadism (congenital or acquired) – Testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, or orchidectomy.

Hypogonadotropic hypogonadism (congenital or acquired) – Gonadotropin or luteinizing hormone-releasing hormone (LHRH) deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation. (Appropriate adrenal cortical and thyroid hormone replacement therapy are still necessary, however, and are actually of primary importance.)

If the above conditions occur prior to puberty, androgen replacement therapy will be needed during the adolescent years for development of secondary sexual characteristics. Prolonged androgen treatment will be required to maintain sexual characteristics in these and other males who develop Depo-Testosterone Cypionate deficiency after puberty.

Safety and efficacy of Depo-Testosterone Cypionate in men with “age-related hypogonadism” (also referred to as “late-onset hypogonadism”) have not been established.

Delayed puberty – Depo-Testosterone Cypionate® (Depo-Testosterone Cypionate Enanthate Injection, USP) may be used to stimulate puberty in carefully selected males with clearly delayed puberty. These patients usually have a familial pattern of delayed puberty that is not secondary to a pathological disorder; puberty is expected to occur spontaneously at a relatively late date. Brief treatment with conservative doses may occasionally be justified in these patients if they do not respond to psychological support. The potential adverse effect on bone maturation should be discussed with the patient and parents prior to androgen administration. An X-ray of the hand and wrist to determine bone age should be obtained every six months to assess the effect of treatment on the epiphyseal centers.

Females

Metastatic mammary cancer – Depo-Testosterone Cypionate® (Depo-Testosterone Cypionate Enanthate Injection, USP) may be used secondarily in women with advancing inoperable metastatic (skeletal) mammary cancer who are one to five years postmenopausal. Primary goals of therapy in these women include ablation of the ovaries. Other methods of counteracting estrogen activity are adrenalectomy, hypophysectomy, and/or antiestrogen therapy. This treatment has also been used in premenopausal women with breast cancer who have benefited from oophorectomy and are considered to have a hormone-responsive tumor. Judgment concerning androgen therapy should be made by an oncologist with expertise in this field.

How should I use Depo-Testosterone Cypionate?

Use Depo-Testosterone Cypionate solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Depo-Testosterone Cypionate solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Depo-Testosterone Cypionate solution refilled.
  • Prime this product before the first use. To prime it, depress the pump 3 times and wash any product that is dispensed down the sink.
  • Depress the pump once to fill the applicator cup. Holding the applicator upright, wipe Depo-Testosterone Cypionate solution steadily up and down onto clean, dry skin in the armpit. If Depo-Testosterone Cypionate solution drips or runs, it can be wiped back up with the applicator cup. Do NOT apply Depo-Testosterone Cypionate solution to other parts of your body (eg, scrotum, penis, stomach, shoulders, upper arms). Do NOT apply it over open sores, wounds, or irritated skin.
  • Do NOT use your fingers or hand to rub the medicine into the skin.
  • You may need to alternate between armpits when applying Depo-Testosterone Cypionate solution. Be sure you understand how to apply Depo-Testosterone Cypionate solution. Contact your doctor or pharmacist if you have questions or concerns about how to apply Depo-Testosterone Cypionate solution.
  • Wash your hands with soap and water immediately after using Depo-Testosterone Cypionate solution.
  • Allow Depo-Testosterone Cypionate solution to dry completely before dressing.
  • After Depo-Testosterone Cypionate solution has dried, cover the application site (eg, with a shirt) to prevent others from coming into contact with Depo-Testosterone Cypionate solution. If direct skin-to-skin contact with another person is expected, wash the application site well with soap and water to remove the medicine.
  • After using Depo-Testosterone Cypionate solution, rinse the applicator with room temperature water and pat it dry with a tissue. Replace the applicator and cap on the bottle for storage.
  • Do NOT get Depo-Testosterone Cypionate solution in your eyes. If you do, rinse thoroughly with water. If eye irritation persists, contact your doctor.
  • Apply Depo-Testosterone Cypionate solution at the same time every morning after showering or bathing, unless your doctor tells you otherwise.
  • If you are also using an antiperspirant or deodorant (stick or roll-on), apply it at least 2 minutes before you apply Depo-Testosterone Cypionate solution.
  • For best results, wait 2 hours after applying Depo-Testosterone Cypionate solution before you wash the application site or swim.
  • If you miss a dose of Depo-Testosterone Cypionate solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Depo-Testosterone Cypionate solution.

Uses of Depo-Testosterone Cypionate in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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This medication is used by men who do not make enough of a natural substance called Depo-Testosterone Cypionate (hypogonadism). Depo-Testosterone Cypionate belongs to a class of drugs known as androgens. Depo-Testosterone Cypionate helps the body to develop and maintain male sexual characteristics (masculinity), such as a deep voice and body hair. It also helps to maintain muscle and prevent bone loss, and is necessary for natural sexual ability/desire.

This drug should not be used by women.

How to use Depo-Testosterone Cypionate nasal

Read the Patient Information Leaflet if available from your pharmacist before you start using Depo-Testosterone Cypionate and each time you get a refill. Follow the illustrated directions for the proper use of this medication. If you have any questions, ask your doctor or pharmacist.

Gently blow your nose before using this medication. Follow the instructions on how to properly prime the bottle if you are using it for the first time.

Use this medication in the nose as directed by your doctor, usually 3 times a day (6 to 8 hours apart). After applying the medication into both nostrils, gently squeeze your nostrils together and lightly massage. Do not apply this medication to other areas of your body. If another part of your body comes in contact with this medication, wash the area with warm water and soap.

Do not blow your nose or sniff for 1 hour after using this medication. Wipe the tip of the applicator with a clean, dry tissue after each use.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Since this drug can be absorbed through the skin and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication.

Tell your doctor if your condition does not improve or if it worsens.

Depo-Testosterone Cypionate description

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Depo-Testosterone Cypionate is a steroid sex hormone found in both men and women. In men, Depo-Testosterone Cypionate is produced primarily by the Leydig (interstitial) cells of the testes when stimulated by luteinizing hormone (LH). It functions to stimulate spermatogenesis, promote physical and functional maturation of spermatozoa, maintain accessory organs of the male reproductive tract, support development of secondary sexual characteristics, stimulate growth and metabolism throughout the body and influence brain development by stimulating sexual behaviors and sexual drive. In women, Depo-Testosterone Cypionate is produced by the ovaries (25%), adrenals (25%) and via peripheral conversion from androstenedione (50%). Testerone in women functions to maintain libido and general wellbeing. Depo-Testosterone Cypionate exerts a negative feedback mechanism on pituitary release of LH and follicle-stimulating hormone (FSH). Depo-Testosterone Cypionate may be further converted to dihydrotestosterone or estradiol depending on the tissue.

Depo-Testosterone Cypionate dosage

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS

One system is applied at about the same time each day. The adhesive side of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS system should be placed on a clean, dry area of skin on the arm, back or upper buttocks immediately upon removal from the protective pouch. DO NOT APPLY TO THE SCROTUM. The area selected should not be oily, damaged, or irritated. The system should be pressed firmly in place with the palm of the hand for about 10 seconds, making sure there is good contact, especially around the edges. In the event that a system should fall off, the same system may be reapplied. If the system comes off after it has been worn for more than 12 hours and it cannot be reapplied, a new system may be applied at the next routine application time. In either case, the daily treatment schedule should be continued. The Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS system should be worn approximately 24 hours and then replaced. To ensure proper dosing, serum Depo-Testosterone Cypionate concentration may be measured 2-4 hours after an application of Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS. If the serum Depo-Testosterone Cypionate concentrations are low, the dosing regimen may be increased to 2 systems. Because of variability in analytical values among diagnostic laboratories, all Depo-Testosterone Cypionate measurements should be performed at the same laboratory.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE

Patients should start therapy with a 6 mg/d system of either Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) or Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE applied daily; if the scrotal area cannot accommodate a 6 mg/d system, a 4 mg/d Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) system should be used. One Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) or Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE system should be placed on clean, dry, scrotal skin. Scrotal hair should be dry-shaved for optimal skin contact. Chemical depilatories should not be used. Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) or Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE should be worn 22-24 hours.

After 3-4 weeks of daily system use, blood should be drawn 2-4 hours after system application for determination of serum total Depo-Testosterone Cypionate. Because of variability in analytical values among diagnostic laboratories, this laboratory work and later analyses for assessing the effect of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE therapy should be performed at the same laboratory.

If patients have not achieved desired results by the end of 6-8 weeks of treatment with any of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products, another form of Depo-Testosterone Cypionate replacement therapy should be considered.

How supplied

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS, Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)), and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE Depo-Testosterone Cypionate transdermal systems contain a Schedule III controlled substance as defined by the Anabolic Steroids Control Act.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS systems are supplied as individually pouched systems, 30 per carton. Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS 5 mg/d (Depo-Testosterone Cypionate Transdermal System) -- each 60 cm2 system contains 328 mg Depo-Testosterone Cypionate USP for nominal dose of 5 mg/day

Carton of 30 Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS 5 mg/d systemsNDC 17314-4717-3

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE systems are supplied as individually pouched systems, 30 per carton.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) 4 mg/d (Depo-Testosterone Cypionate Transdermal System) -- each 40 cm2 system contains 10 mg Depo-Testosterone Cypionate USP for nominal delivery of 4 mg for one day.

Carton of 30 Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) 4 mg/d systems. NDC 17314-4608-3

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE

6 mg/d (Depo-Testosterone Cypionate Transdermal System) -- each 60 cm2 system contains 15 mg Depo-Testosterone Cypionate USP for nominal delivery of 6 mg for one day.

Carton of 30 Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) 6 mg/d systems. NDC 17314-4609-3

Carton of 30 Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE 6 mg/d systemsNDC 17314-2836-3

Storage

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS

Store at controlled room temperature below 25oC (77oF).

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE

Store at room temperature 15-30oC (59-86oF).

Disposal

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products should be discarded in household trash in a manner that prevents accidental application or ingestion by children or pets.

Caution: Federal law prohibits dispensing without prescription.

REFERENCE

1. Matsumoto AM, Sandblom RE, Schoene RB et al. Depo-Testosterone Cypionate replacement in hypogonadal men: Effects on obstructive sleep apnoea, respiratory drives, and sleep. Clin Endocrinol (1985) 22: 713-721.

2. Schneider BK, Pickett CK, Zwillich CW et al. Influence of Depo-Testosterone Cypionate on breathing during sleep. J Appl Physiol (1986) 61: 618-623.

3. Matsumoto AM. Hormonal therapy of male hypogonadism. Endocrinol Metab Clin North Am. (1994) 23: 857-875.

4. Bardin CW, Swerdloff RS, Santen RJ. Androgens: Risks and benefits. J Clin Endocinol Metab (1991) 73: 4-7.

5. Nieschlag E, Wang CCL. Guidelines for the use of androgens in men. Geneva: World Health Organization (1992); 1-16.

6. Walle T, Walle UK, Mathur RS et al. Propranolol metabolism in normal subjects: Association with sex steroid hormones. Curr Pharmacol Ther (1994) 56:127-132.

7. Physicians Generic Rx: The Complete Drug Reference. (1996); II-1972

Depo-Testosterone Cypionate interactions

See also:
What other drugs will affect Depo-Testosterone Cypionate?

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Drug Interactions

Anticoagulants: C-17 substituted derivatives of Depo-Testosterone Cypionate, such as methandrostenolone, have been reported to decrease the anticoagulant requirements of patients receiving oral anticoagulants. Patients receiving oral anticoagulant therapy require close monitoring, especially when androgens are started or stopped.

Oxyphenbutazone: Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.

Insulin: In diabetic patients, the metabolic effects of androgens may decrease blood glucose and therefore, insulin requirements.

Propranolol: In a published pharmacokinetic study of an injectable Depo-Testosterone Cypionate product, administration of Depo-Testosterone Cypionate cypionate led to an increased clearance of propranolol in the majority of men tested.6

Corticosteroids: The concurrent administration of Depo-Testosterone Cypionate with ACTH or corticosteroids may enhance edema formation; thus these drugs should be administered cautiously, particularly in patients with cardiac or hepatic disease.7

Drug/Laboratory Test Interactions

Androgens may decrease levels of thyroxin-binding globulin, resulting in decreased total T. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.

The Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products contain a Schedule III controlled substance as defined by the Anabolic Steroids Control Act.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS is designed for application to arm, back or upper buttocks skin.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE are designed for application to scrotal skin only. Because scrotal skin is at least five times more permeable to Depo-Testosterone Cypionate than other skin sites, Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) or Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE will not produce adequate serum Depo-Testosterone Cypionate concentrations if applied to non-scrotal skin.

Ingestion of Depo-Testosterone Cypionate, or the contents of any of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products will not result in clinically significant serum Depo-Testosterone Cypionate concentrations due to extensive first-pass metabolism. In addition, an intramuscular injection of Depo-Testosterone Cypionate from any of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products will not produce adequate serum Depo-Testosterone Cypionate levels due to its short half-life (about 10 minutes).

Depo-Testosterone Cypionate side effects

See also:
What are the possible side effects of Depo-Testosterone Cypionate?

Adverse events are reported in this section by product. Adverse events reported during use of a given product may occur in patients who are treated with any Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) product.

Adverse Events with Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS

In clinical studies of 457 participants (116 hypogonadal males and 341 healthy adult males) treated for up to 6 weeks with Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS, the most commonly reported adverse events were application site reactions of transient itching (12%) and moderate or severe erythema (3%).

Adverse events reported by less than 1% of Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS users in clinical trials that were of probable or unknown relationship to drug were:

Body as a Whole: abdominal pain, back pain, infection;
Cardiovascular System: congestive heart failure, hypertension, tachycardia;
Digestive System: diarrhea, nausea;
Metabolic and Nutritional System: hyperglycemia, hyperlipemia, hyponatremia;
Musculoskeletal System: arthralgia;
Nervous System: nervousness, depression, dizziness, dry mouth, insomnia, decreased libido, personality disorder, CNS stimulation;
Respiratory System: bronchitis;
Skin System: application site reactions--papules/pustules, edema, vesicles, pain, other--, acne, alopecia, hirsutism;
Urogenital System: abnormal ejaculation, breast pain, dysuria, urinary tract infection, and impaired urination.

Topical Reactions

Of 457 study participants, 3 men (1%) discontinued prematurely because of application site reactions.

There were no clinically significant differences in skin tolerability in younger (<65 years old) and older (³ 65 years old) subjects.

A contact sensitization rate of 0.5% for Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS was observed in a 6-week study of 233 normal male volunteers.

In one study with 14 days of daily use, 42% of patients reported 3 or more detachments of their Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS; of these detachments, 33% occurred during exercise.

Adverse Events with Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal))

In clinical studies of 104 patients treated with Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)), the most common adverse effects reported were local effects. In US clinical trials, most of the 72 patients filling out a daily questionnaire reported scrotal itching, discomfort, or irritation at some time during therapy. Of all the daily questionnaire responses, 7% reported itching, 4% discomfort, and 2% irritation. All topical reactions decreased with duration of use.

The following adverse effects (greater than 1%) were reported in association with Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) therapy in 104 patients using the product for up to three years. These effects are listed in decreasing frequency of occurrence with the percentages of patients reporting the effect in parentheses: Gynecomastia (5%), acne (4%), prostatitis/urinary tract infection (4%), breast tenderness (3%), stroke (2%). For this same patient population, the following adverse effects were reported by 1% of users: memory loss, pupillary dilation, abnormal liver enzymes, scrotal cellulitis, deep vein phlebitis, benign prostatic hyperplasia, rectal mucosal lesion over prostate, hematuria/bladder cancer, papilloma on scrotum, and congestive heart failure.

Adverse Events with Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE

In a pharmacokinetic study in 50 normal men, skin assessment scores following a single 24-hour application of Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE to scrotal skin were similar to those for Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)). Other adverse events reported during the study were headache (6%), dizziness (6%), back pain, pain, nausea, and pustular rash (1% each).

General Adverse Events with Androgen Replacement Therapy

Skin and Appendages: Hirsutism, male pattern baldness, seborrhea, and acne.

Endocrine and Urogenital: Gynecomastia and excessive frequency and duration of penile erections. Oligospermia may occur at high doses.

Fluid and Electrolyte Disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.

Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests. Rare instances of hepatocellular neoplasms and peliosis hepatis have occurred.

Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.

Nervous System: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.

Metabolic: Increased serum cholesterol.

Miscellaneous: Rarely, anaphylactoid reactions.

DRUG ABUSE AND DEPENDENCE

The Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products contain a Schedule III controlled substance as defined by the Anabolic Steroids Control Act.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) TTS is designed for application to arm, back or upper buttocks skin.

Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) and Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE are designed for application to scrotal skin only. Because scrotal skin is at least five times more permeable to Depo-Testosterone Cypionate than other skin sites, Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) or Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) WITH ADHESIVE will not produce adequate serum Depo-Testosterone Cypionate concentrations if applied to non-scrotal skin.

Ingestion of Depo-Testosterone Cypionate, or the contents of any of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products will not result in clinically significant serum Depo-Testosterone Cypionate concentrations due to extensive first-pass metabolism. In addition, an intramuscular injection of Depo-Testosterone Cypionate from any of the Depo-Testosterone Cypionate (Depo-Testosterone Cypionate (transdermal)) products will not produce adequate serum Depo-Testosterone Cypionate levels due to its short half-life (about 10 minutes).

Depo-Testosterone Cypionate contraindications

See also:
What is the most important information I should know about Depo-Testosterone Cypionate?

  • Depo-Testosterone Cypionate 1% is contraindicated in men with carcinoma of the breast or known or suspected carcinoma of the prostate.
  • Depo-Testosterone Cypionate 1% is contraindicated in women who are or may become pregnant, or who are breastfeeding. Depo-Testosterone Cypionate 1% may cause fetal harm when administered to a pregnant woman. Depo-Testosterone Cypionate 1% may cause serious adverse reactions in nursing infants. Exposure of a female fetus or nursing infant to androgens may result in varying degrees of virilization. Pregnant women or those who may become pregnant need to be aware of the potential for transfer of Depo-Testosterone Cypionate from men treated with Depo-Testosterone Cypionate 1%. If a pregnant woman is exposed to Depo-Testosterone Cypionate 1%, she should be apprised of the potential hazard to the fetus.

Active ingredient matches for Depo-Testosterone Cypionate:

Testosterone


List of Depo-Testosterone Cypionate substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Fortesta gel, metered 10 mg/.5g (Endo Pharmaceuticals Inc. (US))
Gel; Topical; Testosterone 2%
Patch; Topical; Testosterone 300 mcg / 24 h (Procter & Gamble)
Intrinsa Transdermal patch 300 micrograms/24hours (Procter & Gamble)
Livensa Transdermal patch 300 micrograms/24hours (Procter & Gamble)
Gel; Topical; Testosterone 1%
Injectable; Injection; Testosterone 100 mg / ml
Injectable; Injection; Testosterone Propionate 100 mg / ml
Injectable; Injection; Testosterone Enanthate 200 mg / ml
Injectable; Injection; Testosterone Propionate 100 mg / ml

References

  1. DailyMed. "TESTOSTERONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "testosterone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "testosterone". http://www.drugbank.ca/drugs/DB00624 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Depo-Testosterone Cypionate are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Depo-Testosterone Cypionate. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

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1 consumer reported time for results

To what extent do I have to use Depo-Testosterone Cypionate before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Depo-Testosterone Cypionate. To get the time effectiveness of using Depo-Testosterone Cypionate drug by other patients, please click here.
Users%
2 weeks1
100.0%


1 consumer reported age

Users%
46-601
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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