What is Dequinone?
Dequinone decreases the formation of melanin in the skin. Melanin is the pigment in skin that gives it a brown color.
Dequinone topical (for the skin) is used to lighten areas of darkened skin such as freckles, age spots, melasma (sun damage), or chloasma (darkened skin caused by hormonal changes).
Dequinone topical may also be used for purposes not listed in this medication guide.
Dequinone indications
Dequinone 4% CREAMNUQUIN HP 4% CREAM, NUQUIN HP 4% GEL, MELPAQUE HP 4% CREAM, MELQUIN HP 4% CREAM and Dequinone (Dequinone 3% topical solution) are indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other undesired areas of melanin hyperpigmentation.
How should I use Dequinone?
Use Dequinone cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Before using Dequinone cream for the first time, apply a small amount to an unbroken patch of skin and check in 24 hours for itching, blistering, or excessive redness or irritation. If these effects develop, contact your doctor as soon as possible and do not use Dequinone cream on other areas.
- Wash and completely dry the affected areas. Gently rub the medicine in until it is evenly distributed. Wash your hands immediately after using Dequinone cream, unless your hands are part of the treated area.
- If you miss a dose of Dequinone cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Dequinone cream.
Uses of Dequinone in details
Dequinone is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.
This medicine works by blocking the process in the skin that leads to discoloration.
How to use Dequinone topical
Follow all directions on the product package, or use as directed by your doctor. Before using, apply a small amount of this medicine to an area of unbroken skin, and check the area within 24 hours for any serious side effects. If the test area is itching, red, puffy, or blistering, do not use this product and contact your doctor. If there is just mild redness, then treatment with this product may begin.
Apply this medication to the affected areas of skin, usually twice daily or as directed by your doctor. This medication is for use on the skin only. If it is used incorrectly, unwanted skin lightening may occur. Avoid getting this product in your eyes or on the inside of your nose or mouth. If you do get this medication in those areas, flush with plenty of water.
This medication may make the treated areas of skin more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing on the treated areas of skin when outdoors.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
Inform your doctor if your condition persists or worsens after 2 months.
Dequinone description
Dequinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. Dequinone has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity. As a result of these concerns, Dequinone has been banned in the EU and UK.
Dequinone dosage
Dequinone Dosage
Generic name: Dequinone 40mg in 1g
Dosage form: gel
See also:
- Dequinone
Topical
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Dequinone® should be applied to the affected areas twice daily, morning and before bedtime or as directed by a physician.
During and after the use of Dequinone®, sun exposure should be limited and a sunscreen agent or protective clothing should be used to cover up the treated areas to prevent regimentation. If no lightening effect is noted after two months of treatment, use of Dequinone® should be discontinued. There is no recommended dosage for children under the age of 12 years of age except under the advice and supervision of a physician.
More about Dequinone (Dequinone topical)
- Side Effects
- During Pregnancy
- Dosage Information
- 0 Reviews – Add your own review/rating
- Drug class: topical depigmenting agents
Consumer resources
Other brands: Dequinone and Sunscreen, Dequinone, Melquin HP, Eldoquin, More... (15)
Professional resources
- Dequinone (FDA)
- Dequinone (AHFS Monograph)
Related treatment guides
- Dermatological Disorders
Dequinone interactions
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What other drugs will affect Dequinone?
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.
Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Dequinone side effects
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What are the possible side effects of Dequinone?
Mild burning, stinging, redness, and dryness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop using Dequinone and tell your doctor right away if any of these unlikely but serious side effects occur: blistering, skin cracking, blue-black darkening of the skin.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Dequinone contraindications
See also:
What is the most important information I should know about Dequinone?
Before using Dequinone topical, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Do not use Dequinone topical on skin that is sunburned, windburned, dry, chapped, or irritated, or on an open wound. It could make these conditions worse. Wait until these conditions have healed before applying Dequinone topical.
Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water.
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Dequinone topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
Active ingredient matches for Dequinone:
Hydroquinone in Tunisia.
List of Dequinone substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Depiwhite (India) | |
| DEPIWHITE cream 15gm (Wockhardt (Derma)) | $ 6.27 |
| Derma-Blanch | |
| Derma-Rx Lightener (Hong Kong) | |
| Dermisa (Peru) | |
| Dermofade | |
| Dermofade Skin 60 ml Lotion (Gary Pharmaceuticals Pvt. Ltd.) | $ 0.78 |
| Dermofade Skin 30 gm Cream (Gary Pharmaceuticals Pvt. Ltd.) | $ 0.43 |
| DERMOFADE CREAM 1 tube / 30 GM cream each (Gary Pharmaceuticals Pvt. Ltd.) | $ 0.46 |
| Dermofade NA Cream (Gary Pharmaceuticals Pvt. Ltd.) | $ 0.46 |
| Dermopaque (Pakistan) | |
| Dermoquin (Pakistan) | |
| Dermoquinn | |
| Dermoquinona (Colombia) | |
| Despigmental (Spain) | |
| Despigmentante (Peru) | |
| Diak 5 | |
| Discromil (Italy) | |
| Domina (South Korea) | |
| Domina 40 mg/1 g x 1 tube 10 g | |
| Domina 4 % x 10 g | |
| Dominakrem (Vietnam) | |
| Dominakrem 40 mg x 1 tube 10 g | |
| EB5 Age Spot Formula | |
| Cream; Topical; Hydroquinone 2% | |
| Eb5 Age Spot Formula cream 2 % (Natural White Inc. (Canada)) | |
| Ecladerm | |
| Eldopaque Forte 4% (Egypt) | |
| Eldoquin 2% (Egypt) | |
| Eldoquin Forte 4% (Egypt) | |
| Eldoquin Forte 亮膚雪 (Hongkong) | |
| Eldoquine (Lebanon) | |
| Eldoquine forte (Lebanon) | |
| EPILITE | |
| EPILITE 5% LOTION 1 bottle / 40 ML lotion each (Percos India Pvt Ltd) | $ 1.43 |
| EpiQuin (United States) | |
| EPIQUIN tab 300 mg x 10's (Alpic (Eucrasia)) | $ 0.72 |
| Eqinon (Indonesia) | |
| Eqinon 4 % x 15 g x 1's | $ 1.36 |
| Eqinon Forte 5 % x 15 g x 1's | $ 1.49 |
| Eqinon/Eqinon Forte (Indonesia) | |
| ESLITE (India) | |
| ESLITE Cream/ Gel/ Ointment / 0.02 / 20gm units (Elder) | $ 0.31 |
| Eslite 2% w/w CRM / 20g (Elder) | $ 0.31 |
| 2 % w/w x 20g (Elder) | $ 0.31 |
| ESLITE 2% CREAM 1 tube / 15 GM cream each (Elder) | $ 0.54 |
| ESLITE cream 2 % w/w x 20g (Elder) | $ 0.31 |
| Eslite 2% w/w CRM / 20g (Elder) | $ 0.31 |
| Esomed (Israel) | |
| Esomed Body Cream | |
| Cream; Topical; Hydroquinone 2% | |
| Esomed Gel | |
| Gel; Topical; Hydroquinone 4% | |
See 403 substitutes for Dequinone | |
References
- DailyMed. "FLUOCINOLONE ACETONIDE; HYDROQUINONE; TRETINOIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "hydroquinone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "hydroquinone". http://www.drugbank.ca/drugs/DB09526 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Dequinone are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dequinone. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
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Information checked by Dr. Sachin Kumar, MD Pharmacology
